scholarly journals ACTA NON VERBA (ON THE OCCASION OF THE ANNIVERSARY OF PROF. OKSANA ZAYACHKIVSKA)

Author(s):  
Ulyana Pidvalna ◽  

Oksana Stanislavivna Zayachkivska (born on July 24, 1960, Lviv) – Doctor of Medicine, Professor (2008), Head of the Department of Normal Physiology (2016) at Danylo Halytsky Lviv National Medical University. She is a full member of Shevchenko Scientific Society (SSS) (2018), chairman of the Medical Commission of SSS (2015-2018), Member of the Physiological Society (UK), Global GI Club in FASEB, International Union of Basic and Clinical Pharmacology (IUPHAR-GI section), Honorary Ambassador of Lviv (2019–21). Her ​​research is mainly focused on the problems of the physiology of digestion, stress and the creation of preclinical models of gastrointestinal diseases. Professor studies new stress biomarkers, anti-stress agents and the formation of stress resistance; elucidates molecular mechanisms of cytoprotection. Oksana Zayachkivska is the author and co-author of over 300 scientific original works and translations of the English-language professional literature. She is the member of the Editorial Board and Editor-in-Chief of the “Proceedings of the Shevchenko Scientific Society. Medical Sciences” journal (2015–2020), member of the Editorial boards of “Frontier in Pharmacology” (Switzerland), “Southeast European Medical Journal” (Croatia), “Journal of Clinical Gastroenterology” (USA).

Author(s):  
Oksana Zayachkivska ◽  
◽  
Marta Kovalska ◽  

We would like to thank our past and present editorial and production teams and our authors for cooperation in 2020. Despite of COVID-19 challenges in 2020, our journal has recently received acceptations to the Directory of Open Access Journals (DOAJ) and in processing to Ulrichsweb & Ulrichs Periodicals Directory. The Proceedings of Shevchenko Scientific Society. Medical Sciences obtains manuscripts over the world [1-8]. The decision on their publications is based on potentially influential contents of interest to Ukrainian and other medical and healthcare professionals, scientists and medical students after successful critical peer review [9]. All of the editorial staff of The Proceedings of Shevchenko Scientific Society. Medical Sciences sincerely appreciates the authors’ contributions. Among them, the best corresponding authors (based on download counts of their articles and positive social media attention) are Dr. Sandor Szabo (American University Health Science, CA, USA) and Dr. Natalia Matolinets (Danylo Halytsky Lviv National Medical University, Lviv, Ukraine). In 2020, The Proceedings of Shevchenko Scientific Society. Medical Sciences has put all efforts to upgrade the Journal peer review standards, offering regular educational courses/webinars to advance their editorial credentials to better serve the professional interests of the Journal readers. The Proceedings of Shevchenko Scientific Society. Medical Sciences invited new editorial board members and experts for peer review of the manuscripts in 2020, and some of them received multiple invitations. We honestly appreciate the voluntary contribution of all of the members of the editorial team, executive, and editorial boards of PSSS MS and all reviewers as introduced below. Among reviewers, top peer reviewers (based on their contribution of 4 or more reviews) are Dr. Andriy Cherkas (Sanofi-Aventis-Deutschland GmbH – Industriepark Höchst, Frankfurt am Main, Germany), Dr. Nelia Oryshchyn (Danylo Halytsky Lviv National Medical University, Lviv, Ukraine), Dr. Vassyl Lonchyna (University of Chicago Pritzker School of Medicine, Chicago, United States).


Welcome to the new issue of the Contemporary Military Challenges, which differs from others. The most loyal readers will soon notice that they already know the authors and that the discussed subjects are not really topical. Strange? Not really. This issue concludes the period, very important for military literature in Slovenia. We have been issuing our publication for fifteen years. Originally titled Slovenian Armed Forces Bulletin, the publication was later renamed Contemporary Military Challenge. This time, the publication, issued by the General Staff of the Slovenian Armed Forces, is devoted to executive and managing editors who have contributed to the creation of the publication in the past. According to the Editorial Board, they have probably been the ones most responsible and certainly persistent enough to provide for a continued issuing of the publication. Still more, with time, the publication was issued more frequently and regularly, while the level of quality increased. Upon its fifteenth anniversary, we wish to extend our appreciation to all who have in any way contributed to the creation of this publication. On this occasion, we have collected the editorials of executive and managing editors, marking important anniversaries or changes in our publication, as well as some of the first articles written for this publication. In the first part, the editorials point to the main three reasons, which led the then Chief of the General Staff of the Slovenian Armed Forces to prepare the first issue of the publication. All other editorials, however, give a detailed description of the purpose and goals of the publication. They offer a short review of the work accomplished by the editorial boards, illustrate the current situation and provide a look ahead. It is our firm belief that such presentation best reflects the development of the publication on its anniversary. The majority of executive and managing editors have also made the effort to write for the publication, thus setting an example for the creation of military professional literature. They have built and developed their professional, some of them also their academic, careers. Their early works, published in the second part of this jubilee issue, present the approaches and motives leading to the reflexions about the military then and in the future. A special chapter is devoted to the presentation of authors and their career paths. I extend my sincere gratitude to all executive and managing editors for their contribution to the development of the publication; all members of editorial boards for the invested effort; proof-readers for their care for the Slovenian language; translators for the quality transfer of Slovenian thoughts into the international environment, and all those who have never been mentioned, but have made the issuing of the final product possible. We continue to count on all of those who have cooperated with us so far and, of course, on those would wish to do so in the future. The Contemporary Military Challenges will serve as the opportunity to share our knowledge, findings and experiences with those employed with the Slovenian Armed Forces as well as those from the wider environment. This will provide us with an opportunity to prove our expertise, which was the aim of the first and all of the following executive and managing editors. Since 2010, the Contemporary Military Challenges has been indexed in an international database, which means that the publication has been recognised both scientifically and professionally. Our goal is to index the publication in additional databases as well as to expand and enhance cooperation with other editorial boards.


2019 ◽  
Vol 18 (2) ◽  
Author(s):  
Chief Editor Of Anterior J

Assalamu�alaikum Wr. Wb.Dear reader, now ANTERIOR JURNAL re-published on Volume 18 Issue 2 June 2019. The success of this publication is the result of good cooperation of all parties who maintain the publishing sustainability twice a year. This edition is also our latest edition, publishing articles with a multidisciplinary scope, starting from volume 19 Issue 1 December 2019, all articles in the ANTERIOR JURNAL are only focused on the Social-Humanities scope, covering all fields of education, social and political, Islamic studies and other relevant topics. In this edition, we are still publishing four articles in the field of agrotechnology and engineering, which will be the last time we publish articles in the field of science at the ANTERIOR JURNAL.Alhamdulillah, from this edition ANTERIOR JURNAL achieved a new milestone by publishing two English-language articles. We hope this will be a step forward for the future internationalization of the Journal.The publication of ANTERIOR JURNAL certainly participates in disseminating the results of research and review of science and technology development conducted by lecturers and researchers especially from UM Palangkaraya and other universities.This edition contains 12 articles consisting of Education, Social and Political, Islamic Studies, Engineering, and Agrotechnology topics. Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions.The editorial board would like to thank the University, all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors of the articles, could re-participate for the success of the publication in the next edition in December 2019. Wassalamu�alaikum Wr. Wb.


2019 ◽  
Vol 19 (3) ◽  
pp. 247-258 ◽  
Author(s):  
Mahsa Hatami ◽  
Mina Abdolahi ◽  
Neda Soveyd ◽  
Mahmoud Djalali ◽  
Mansoureh Togha ◽  
...  

Objective: Neuroinflammatory disease is a general term used to denote the progressive loss of neuronal function or structure. Many neuroinflammatory diseases, including Alzheimer’s, Parkinson’s, and multiple sclerosis (MS), occur due to neuroinflammation. Neuroinflammation increases nuclear factor-κB (NF-κB) levels, cyclooxygenase-2 enzymes and inducible nitric oxide synthase, resulting in the release of inflammatory cytokines, such as interleukin-6 (IL-6), interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α). It could also lead to cellular deterioration and symptoms of neuroinflammatory diseases. Recent studies have suggested that curcumin (the active ingredient in turmeric) could alleviate the process of neuroinflammatory disease. Thus, the present mini-review was conducted to summarize studies regarding cellular and molecular targets of curcumin relevant to neuroinflammatory disorders. Methods: A literature search strategy was conducted for all English-language literature. Studies that assessed the various properties of curcuminoids in respect of neuroinflammatory disorders were included in this review. Results: The studies have suggested that curcuminoids have significant anti- neuroinflammatory, antioxidant and neuroprotective properties that could attenuate the development and symptom of neuroinflammatory disorders. Curcumin can alleviate neurodegeneration and neuroinflammation through multiple mechanisms, by reducing inflammatory mediators (such as TNF-α, IL-1β, nitric oxide and NF-κB gene expression), and affect mitochondrial dynamics and even epigenetic changes. Conclusion: It is a promising subject of study in the prevention and management of the neuroinflammatory disease. However, controlled, randomized clinical trials are needed to fully evaluate its clinical potential.


2019 ◽  
Vol 77 (9) ◽  
Author(s):  
Narges Dastmalchi ◽  
Seyed Mahdi Banan Khojasteh ◽  
Mirsaed Miri Nargesi ◽  
Reza Safaralizadeh

ABSTRACT Helicobacter pylori infection performs a key role in gastric tumorigenesis. Long non-coding RNAs (lncRNAs) have demonstrated a great potential to be regarded as effective malignancy biomarkers for various gastrointestinal diseases including gastric cancer (GC). The present review highlights the relationship between lncRNAs and H. pylori in GC. Several studies have examined not only the involvement of lncRNAs in H. pylori-associated GC progression but also their molecular mechanisms of action. Among the pertinent studies, some have addressed the effects of H. pylori infection on modulatory networks of lncRNAs, while others have evaluated the effects of changes in the expression level of lncRNAs in H. pylori-associated gastric diseases, especially GC. The relationship between lncRNAs and H. pylori was found to be modulated by various molecular pathways.


Cells ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1331
Author(s):  
Alexane Ollivier ◽  
Maxime M. Mahe ◽  
Géraldine Guasch

The gastrointestinal tract is a continuous series of organs from the mouth to the esophagus, stomach, intestine and anus that allows digestion to occur. These organs are frequently associated with chronic stress and injury during life, subjecting these tissues to frequent regeneration and to the risk of developing disease-associated cancers. The possibility of generating human 3D culture systems, named organoids, that resemble histologically and functionally specific organs, has opened up potential applications in the analysis of the cellular and molecular mechanisms involved in epithelial wound healing and regenerative therapy. Here, we review how during normal development homeostasis takes place, and the role of the microenvironmental niche cells in the intestinal stem cell crypt as an example. Then, we introduce the notion of a perturbed niche during disease conditions affecting the esophageal–stomach junction and the colon, and describe the potential applications of organoid models in the analysis of human gastrointestinal disease mechanisms. Finally, we highlight the perspectives of organoid-based regenerative therapy to improve the repair of the epithelial barrier.


2018 ◽  
Vol 2018 ◽  
pp. 1-12
Author(s):  
Baojin Yao ◽  
Bocheng Lu ◽  
Mei Zhang ◽  
Hongwei Gao ◽  
Xiangyang Leng ◽  
...  

Traditional Chinese medicine is one of the oldest medical systems in the world and has its unique principles and theories in the prevention and treatment of human diseases, which are achieved through the interactions of different types of materia medica in the form of Chinese medicinal formulations. GZZSZTW, a classical and effective Chinese medicinal formulation, was designed and created by professor Bailing Liu who is the only national medical master professor in the clinical research field of traditional Chinese medicine and skeletal diseases. GZZSZTW has been widely used in clinical settings for several decades for the treatment of joint diseases. However, the underlying molecular mechanisms are still largely unknown. In the present study, we performed quantitative proteomic analysis to investigate the effects of GZZSZTW on mouse primary chondrocytes using state-of-the-art iTRAQ technology. We demonstrated that the Chinese medicinal formulation GZZSZTW modulates chondrocyte structure, dynamics, and metabolism by controlling multiple functional proteins that are involved in the cellular processes of DNA replication and transcription, protein synthesis and degradation, cytoskeleton dynamics, and signal transduction. Thus, this study has expanded the current knowledge of the molecular mechanism of GZZSZTW treatment on chondrocytes. It has also shed new light on possible strategies to further prevent and treat cartilage-related diseases using traditional Chinese medicinal formulations.


2017 ◽  
Vol 176 (6) ◽  
pp. R283-R308 ◽  
Author(s):  
Evanthia Diamanti-Kandarakis ◽  
Maurizio Dattilo ◽  
Djuro Macut ◽  
Leonidas Duntas ◽  
Efstathios S Gonos ◽  
...  

Aging and its underlying pathophysiological background has always attracted the attention of the scientific society. Defined as the gradual, time-dependent, heterogeneous decline of physiological functions, aging is orchestrated by a plethora of molecular mechanisms, which vividly interact to alter body homeostasis. The ability of an organism to adjust to these alterations, in conjunction with the dynamic effect of various environmental stimuli across lifespan, promotes longevity, frailty or disease. Endocrine function undergoes major changes during aging, as well. Specifically, alterations in hormonal networks and concomitant hormonal deficits/excess, augmented by poor sensitivity of tissues to their action, take place. As hypothalamic–pituitary unit is the central regulator of crucial body functions, these alterations can be translated in significant clinical sequelae that can impair the quality of life and promote frailty and disease. Delineating the hormonal signaling alterations that occur across lifespan and exploring possible remedial interventions could possibly help us improve the quality of life of the elderly and promote longevity.


2021 ◽  
Vol 28 ◽  
pp. 7-12
Author(s):  
Joanna Basiaga-Pasternak ◽  
Jan Blecharz

In the text, it is shows how the journal – Studia Humanistyczne [Eng. Humanistic Studies] has changed, initially published as Zeszyty Naukowe [Eng. Scientifi c Notebooks], then as an independent periodical, to fi nally assume the form of the English-language Studies in Sport Humanities. The stages of the Journal’s operation, managed by successive Editors-in-Chief, were presented. It was showed who comprised the Editorial Board and what modifi cations the Journal underwent to fi nally take the present form of international Studies in Sport Humanities.


Author(s):  
Mike Downes

Introduction. OMICS is the largest and most successful predatory publisher, with numerous subsidiaries. In 2019 it was convicted of unethical publishing practices. Method. A numerical tally of OMICS's editorial listings was compiled across 131 nations. Names and affiliations were recorded for seven nations. A sample was surveyed to estimate the proportions of those aware and unaware of their listing, and of OMICS’s conviction. Analysis. Excel enabled compilation, absolute and proportional tallies and random selection. Results. OMICS has twenty subsidiaries and 26,772 editor (and editorial board) listings, 11,361 from just seven nations. Proportional to population, Greeks were most frequently represented on OMICS's editorial boards, followed by Americans, Singaporeans and Italians. In absolute terms, Americans were the most numerous. The survey found that more than half of the respondents were either unaware of their listing or were unwilling to be listed, and 26% were unaware of OMICS’s conviction. Conclusion. OMICS's editorial boards do not function as they do for respectable publishers, hence the information published in OMICS journals is unreliable. Academic alliances with OMICS are potentially damaging to academic careers and institutional reputations. Universities should develop policies dealing with predatory publishers in general and OMICS in particular.


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