ROLE OF HISTAMINE IN GASTRIC SECRETION: FROM DISCOVERY TO CLINICAL APPLICATION (A Tribute Leon Popielski To 150-Anniversary From His Birth)

2016 ◽  
Vol 47 (2) ◽  
pp. 18-27
Author(s):  
Oksana Zayachkivska ◽  
◽  
Anna Musiol ◽  
Iryna Muzyka
Keyword(s):  
Gastric Secretion ◽  
Clinical Application

The role of elevated levels of microRNA-155-5p and microRNA-124-5p in hyperuricemia and acute ischemic stroke

2021 ◽  
Vol 11 (10) ◽  
pp. 1674-1680
Author(s):  
Yuan Yao ◽  
Jun Yuan ◽  
Yanju Ma ◽  
Runxiu Zhu ◽  
Yong Ma
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Clinical Application ◽  
Cerebral Vasospasm ◽  
Rat Model ◽  
Inner Mongolia ◽  
Neuronal Apoptosis ◽  
Projection Neuron ◽  
Neuron Differentiation

Hyperuricemia is closely related to acute ischemic stroke (AIS). In our study, we investigated the pattern of miRNA-155-5p and miRNA-124-5p expressions along with its clinical application in AIS and hyperuricemia patients and in a hyperuricemia rat model by RT-qPCR. The hyperuricemia rat model was established, and we found that the levels of miRNA-155-5p and miRNA-124-5p were increased in the serum, brain and kidney tissues compared with those in the normal rats. We proved that the levels of miRNA-155-5p and miRNA-124-5p were also elevated in AIS, hyperuricemia and AIS accompanied with hyperuricemia patients enrolled from the department of neurology in Inner Mongolia People’s Hospital (IMPH). The miRNA-155-5p and miRNA-124-5p were mainly associated with neuronal apoptosis, cerebral vasospasm, neuron projection, neuron projection morphogenesis, neuron differentiation and exocytosis. The above results might provide clues for the study the pathogenesis of AIS and hyperuricemia.

Role of the Pyloric Antrum in Regulation of Gastric Secretion

1960 ◽  
Vol 40 (3) ◽  
pp. 490-504 ◽  
Author(s):  
E. R. Woodward ◽  
L. R. Dragstedt
Keyword(s):  
Gastric Secretion ◽  
Pyloric Antrum

The role of microRNA-26a in human cancer progression and clinical application

Tumor Biology ◽  
2016 ◽  
Vol 37 (6) ◽  
pp. 7095-7108 ◽  
Author(s):  
Jing Chen ◽  
Kai Zhang ◽  
Yuejuan Xu ◽  
Yanping Gao ◽  
Chen Li ◽  
...  
Keyword(s):  
Clinical Application ◽  
Cancer Progression ◽  
Human Cancer

scholarly journals Cures That (Make You) Work

2021 ◽  
Vol 229 (3) ◽  
pp. 171-177 ◽  
Author(s):  
Jana S. Aengenheister ◽  
Renée Urban ◽  
Georg Halbeisen
Keyword(s):  
Clinical Application ◽  
Social Perception ◽  
Social Role ◽  
Health Benefits ◽  
Behavioral Changes ◽  
Total N ◽  
Health Related Behaviors ◽  
Headache Treatment ◽  
Health Related

Abstract. Successful treatment not only depends on adhering to taking medication and attending therapy but also on behavioral changes. In two experiments (total N = 256), we investigated the hypothesis that the perceived social role of a treatment as partner (co-producer of a health-benefits) or servant (sole provider of health benefits) could promote or prevent intentions to engage in health-related behaviors. Specifically, we used headache treatment as an everyday example and found that participants were more inclined to engage in headache-reducing behaviors when painkillers were described as partners as compared to servants. Implications of these findings for the importance of anthropomorphic social perception in the clinical application are discussed.

A new role of phosphopeptides as bioactive peptides released during milk casein digestion in the young mammal: Regulation of gastric secretion

Peptides ◽  
2009 ◽  
Vol 30 (12) ◽  
pp. 2221-2227 ◽  
Author(s):  
Paul Guilloteau ◽  
Véronique Romé ◽  
Luc Delaby ◽  
François Mendy ◽  
Loic Roger ◽  
...  
Keyword(s):  
Gastric Secretion ◽  
Bioactive Peptides ◽  
Milk Casein

scholarly journals Clinical Significance of Circulating Tumor Cells in Gastrointestinal Carcinomas

Diagnostics ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 192
Author(s):  
Leonie Konczalla ◽  
Anna Wöstemeier ◽  
Marius Kemper ◽  
Karl-Frederik Karstens ◽  
Jakob Izbicki ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Clinical Application ◽  
Liquid Biopsy ◽  
Cancer Diagnostics ◽  
Therapeutic Approaches ◽  
Primary Tumors ◽  
New Therapeutic Approaches ◽  
Tumor Dissemination

The idea of a liquid biopsy to screen, surveil and treat cancer patients is an intensively discussed and highly awaited tool in the field of oncology. Despite intensive research in this field, the clinical application has not been implemented yet and further research has to be conducted. However, one component of the liquid biopsy is circulating tumor cells (CTCs) whose potential for clinical application is evaluated in the following. CTCs can shed from primary tumors to the peripheral blood at any time point during the progress of a malignant disease. Following, one single CTC can be the origin for distant metastasis at later cancer stage. Thus, CTCs have great potential to either be used in cancer diagnostics and patient stratification or to function as a target for new therapeutic approaches to stop tumor dissemination and metastasis at the very early beginning. Due to the biological fundamental role of CTCs in tumor progression, here, we provide an overview of CTCs in gastrointestinal cancers and their potential use in the clinical setting. In particular, we discuss the usage of CTC for screening and stratifying patients’ risk. Moreover, we will discuss the potential role of CTCs for treatment specification and treatment monitoring.

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