scholarly journals Reliability Assessment of the Endoscopic Examination in Patients with Allergic Rhinitis

2016 ◽  
Vol 7 (3) ◽  
pp. ar.2016.7.0176
Author(s):  
Georges K. Ziade ◽  
Reem A. Karami ◽  
Ghina B. Fakhri ◽  
Elie S. Alam ◽  
Abdul Latif Hamdan ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Endoscopic Examination ◽  
Nasal Endoscope ◽  
Mild Disease ◽  
Endoscopic Findings ◽  
Interrater Variability ◽  
Mucosal Edema ◽  
Nasal Secretions ◽  
A Prospective Study ◽  
Bluish Discoloration

Objective To study if nasal endoscope can be a reliable tool in assessing patients with allergic rhinitis. Materials and Methods A prospective study. Patients who were diagnosed with allergic rhinitis underwent a nasal endoscopic examination performed by two physicians blinded to the scoring of each other. A correlation was made among symptom severity, endoscopic findings, and interrater variability. Results Ninety patients were included in the study: 34 patients had mild disease and 56 had moderate-to-severe allergic rhinitis according to the Allergic Rhinitis and its Impact on Asthma guidelines. Increases in mucosal edema and bluish discoloration were predictive of the severity of allergic rhinitis disease (p < 0.05). The presence of nasal secretions was not predictive of allergic rhinitis. Interrater reliability was fair for mucosal edema, moderate-to-almost perfect for the rest of the endoscopic findings. Conclusion Nasal endoscopy may reveal signs that are predictive of the severity of allergic rhinitis. A detailed checklist is needed for the nasal endoscopic examination to decrease interrater variability.

scholarly journals Nasal Endoscopic Findings in Allergic Rhinitis: A Prospective Study

2014 ◽  
Vol 13 (5) ◽  
pp. 45-48
Author(s):  
Dr Sujeet Kumar ◽  
◽  
Dr Ramanuj Singh ◽  
Dr Manish Kr Singh ◽  
Dr Subrata Nag
Keyword(s):  
Allergic Rhinitis ◽  
Prospective Study ◽  
Endoscopic Findings ◽  
A Prospective Study

scholarly journals A Description of Treatment Patterns of Psoriasis by Medical Providers and Disease Severity in US Women

2020 ◽  
pp. 247553032097053
Author(s):  
Mahroo Tajalli ◽  
Tricia Li ◽  
Aaron M. Drucker ◽  
Abrar A. Qureshi ◽  
Eunyoung Cho
Keyword(s):  
Systemic Therapy ◽  
Topical Treatment ◽  
Severe Disease ◽  
Treatment Patterns ◽  
Health Study ◽  
Mild Disease ◽  
Improved Outcomes ◽  
A Prospective Study ◽  
Female Nurses ◽  
Topical Medications

Background: Studies on treatment patterns of psoriasis are valuable to evaluate how efficiently individuals with psoriasis are treated and may facilitate improved outcomes for these patients. Objective: To describe treatment patterns of psoriasis among US women. Methods: In the Nurses’ Health Study II (NHS II), a prospective study of female nurses, 2107 women reported to have a diagnosis of psoriasis made by a clinician. We sent them the Psoriasis Screening Tool-2, a validated diagnostic tool for psoriasis, which queries age at diagnosis, treatments, type of psoriasis lesions, body surface area involved, and the provider who made the diagnosis. Results: A total of 1382 women completed and returned the survey, with 1243 of them validated for having psoriasis. 30% of the patients were diagnosed by non-dermatologists. 79% of the patients reported mild, 17% moderate and 4% severe disease. Psoriasis phenotypes were as follows: plaque 41%, scalp 49%, inverse 27%, nail 22% and palmoplantar 15%. Treatment patterns for mild psoriasis were as follows: only topical treatment 58%, systemic therapy and/or phototherapy 16% and no treatment 26%. Treatment patterns for moderate-to-severe disease were as follows: only topical treatment 42%, systemic therapy and/or phototherapy 47% and no treatment 11%. Conclusion: The majority of women in NHS II with psoriasis have mild disease. A large proportion of psoriasis patients were diagnosed by non-dermatologists. More than half of people with moderate-to-severe disease received no treatment or only topical medications. A considerable percentage of people with psoriasis reported phenotypes other than chronic plaque psoriasis.

scholarly journals Probiotic therapy on children with allergic rhinitis

2016 ◽  
Vol 53 (5) ◽  
pp. 264
Author(s):  
Franky Luhulima ◽  
IPG Karyana ◽  
Sumadiono Sumadiono
Keyword(s):  
Allergic Rhinitis ◽  
Placebo Group ◽  
Standard Therapy ◽  
Controlled Trial ◽  
Nasal Symptom ◽  
Probiotic Supplementation ◽  
Double Blind ◽  
Probiotic Group ◽  
Probiotic Treatment ◽  
Nasal Secretions

phils in nasal secretions of patients with allergic rhinitis may cause persistent nasal blockage. A common therapy for allergic rhinitis is oral or intranasal corticosteroids. However, corticosteroids carry the risk of disrupting growth and development in children. Probiotic treatment in allergic rhinitis patients works by manipulating the bacterial ecosystem of the digestive tract, stimulating the balance of Th1 and Th2 immune responses.Objective To assess the effects of probiotic supplementation on eosinophil levels in nasal secretions, duration of allergic episodes, and total nasal symptom scores in children aged 2-18 years with allergic rhinitis.Methods A randomized, double-blind, controlled trial was performed on children aged 2 to 18 years who visited Sanglah Hospital, Denpasar, between March to July 2012 due to allergic rhinitis. Fifty-five eligible subjects were involved in the study. Subjects were randomly allocated to receive either standard therapy (antihistamines) and probiotics or standard therapy and placebo for 30 days. Mann-Whitney test was used for statistical non-parametric unpaired samples analysis. P values of <0.05 were considered to be statistically significant.Results Fifty-five subjects with allergic rhinitis were randomized into either the probiotic group (27 subjects) or the placebo group (28 subjects). We found that the median (range) nasal eosinophil percentage reduction before the study compared to after 30 days of treatment was higher in the probiotic group than in the placebo group (34 (15-65) vs 6 (0-24) %, respectively, P<0.0001). Median (range) duration of allergic rhinitis episode in the probiotic group was shorter compared to the placebo group (48 (0-96) hours vs 72 (6-168) hours, respectively; P<0.0001). The median (range) total nasal symptom score was also lower in the probiotic group compared to the placebo group (2 (0-3) vs 5 (1-6), respectively; P<0.0001).Conclusion Probiotic supplementation reduces the percentage of nasal eosinophils, duration of allergic rhinitis episode, and total nasal symptoms.

A Prospective Study of Outcomes of Septoplasty with Turbinate Reductions in Patients with Allergic Rhinitis

2019 ◽  
Vol 160 (6) ◽  
pp. 1118-1123 ◽  
Author(s):  
Grant S. Gillman ◽  
Giuseppe V. Staltari ◽  
Yue-Fang Chang ◽  
Jose L. Mattos
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
Nasal Obstruction ◽  
Symptomatic Relief ◽  
Inferior Turbinate ◽  
University Hospital ◽  
Life Questionnaire ◽  
Related Quality ◽  
A Prospective Study

Objective Examine outcomes of septoplasty with turbinate reductions in patients with allergic rhinitis as compared to patients without allergic rhinitis using validated outcome and quality-of-life (QOL) instruments. Study Design Prospective observational cohort study. Setting Single surgeon, university hospital. Subjects and Methods Consecutive study-eligible patients with a symptomatic nasal septal deviation, with (n = 30) or without (n = 30) documented allergic rhinitis, were enrolled from March 2014 to February 2017. All patients subsequently underwent nasal septoplasty and inferior turbinate reductions. Outcomes were studied using the Nasal Obstruction Symptom Evaluation (NOSE) scale, mini–Rhinoconjunctivitis Quality of Life Questionnaire (mini-RQLQ), and Ease-of-Breathing (EOB) Likert scores completed preoperatively and, together with a patient satisfaction Likert, at 3 and 6 months postoperatively. Results NOSE scores, EOB scores, and mini-RQLQ scores improved significantly in both groups at 3 and 6 months postoperatively. Results were sustained from 3 to 6 months. Although mini-RQLQ scores in allergic patients were higher at all intervals, the magnitude of change in scores in both groups was comparable. Conclusion Although patients with allergic rhinitis report greater allergy-related QOL impairment (mini-RQLQ) on a day-to-day basis than nonallergic patients, this does not appear to attenuate the benefit they might experience from septoplasty and turbinate reductions when indicated for nasal obstruction. Furthermore, the symptomatic relief of their structural nasal obstruction appears to significantly improve their overall allergy-related quality of life. If appropriate expectations are set pre-operatively, allergic rhinitis is neither a contraindication nor a deterrent to septoplasty and turbinate reductions and these patients can reasonably expect a high degree of satisfaction post-operatively.

Quantitative Cytology of Nasal Secretions With Perennial Allergic Rhinitis in Children: Comparison of Noninfected and Infected Conditions

1998 ◽  
Vol 108 (5) ◽  
pp. 703-705 ◽  
Author(s):  
Jun Shinogi ◽  
Yuichi Majima ◽  
Kazuhiko Takeuchi ◽  
Teruhiko Harada ◽  
Yasuo Sakakura
Keyword(s):  
Allergic Rhinitis ◽  
Perennial Allergic Rhinitis ◽  
Quantitative Cytology ◽  
Nasal Secretions

scholarly journals Treatment Evaluation with Mometasone Furoate, Alone or in Combination with Desloratadine/ Montelukast in Moderate Severe Allergic Rhinitis

2014 ◽  
Vol 60 (3) ◽  
pp. 106-108 ◽  
Author(s):  
Nona-Aura Florincescu-Gheorghe ◽  
Florica Popescu ◽  
D.O. Alexandru
Keyword(s):  
Allergic Rhinitis ◽  
Allergic Inflammation ◽  
Allergic Diseases ◽  
Nasal Secretion ◽  
Mometasone Furoate ◽  
Line Treatment ◽  
First Line ◽  
Nasal Symptoms ◽  
A Prospective Study ◽  
First Line Treatment

Abstract Introduction: Allergic rhinitis is one of the most common allergic diseases, characterized by the inflammation of the nasal mucosa. Eosinophils play a predominant pro-inflammatory role in allergic inflammation. This study assesses the effect of mometasone furoate alone or in combination with desloratadine/montelukast in patients with moderate-severe allergic rhinitis. Material and method: This is a prospective study that took place over 8 weeks on 70 patients diagnosed with moderate-severe allergic rhinitis with sensitization to the pollen of Ambrosia elatior. The patients were evaluated on the basis of their symptoms using the total score of nasal symptoms, the score of individual nasal symptoms and the number of eosinophils in the nasal secretion. Results: All 3 groups of patients had an improvement on the total nasal symptoms score. However, the combination of mometasone furoate with desloratadine provided statistically significant benefits on the total score of symptoms and on nasal itching as compared with mometasone furoate alone. Conclusions: The association of mometasone furoate with desloratadine should be considered first-line treatment of moderate-severe allergic rhinitis due to the benefit both on the total symptom score and on of nasal itching.

scholarly journals Association of Endoscopic Features of Gastric Mucosa withHelicobacter pyloriInfection in Chinese Patients

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Tao Mao ◽  
Yan Wang ◽  
Fan Yin ◽  
Qingxi Zhao ◽  
Lin Yang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Gastric Mucosa ◽  
Endoscopic Examination ◽  
Chinese Patients ◽  
Pathological Examination ◽  
Type I ◽  
Type D ◽  
Mucosal Edema ◽  
H Pylori ◽  
Hematoxylin Eosin

The aim of this study is to identify and consolidate reliable endoscopic features associated withH. pyloriinfection in gastric mucosa, which is one of the major causes of gastric cancer. A total of 256 Chinese patients with symptomatic stomach disturbances were enrolled. Pathological examination was conducted using a light microscope and biopsy specimens stained with hematoxylin-eosin. Endoscopic examination was performed using a high resolution video endoscope. The association between endoscopic features and pathologicalH. pyloridiagnosis was compared, and endoscopic features significantly associated withH. pyloriinfection were identified. A total of 14 endoscopic features were observed. Six of the 14 endoscopic features, including mucus on the gastric mucosa, diffuse redness, spotty redness of fundic mucosa, enlarged fold, mucosal edema, and RAC (type D and type I), were highly associated withH. pyloriinfection and were significantly sensitive and specific predictors forH. pyloridiagnosis. The type R RAC was not significantly associated withH. pyloridiagnosis. Our results indicate that conventional endoscopy features can be used to diagnoseH. pyloriin Chinese patients and can help determine the risk factor for gastric cancer.

Nonselective chemokine levels in nasal secretions of patients with perennial nonallergic and allergic rhinitis

2015 ◽  
Vol 6 (4) ◽  
pp. 392-397 ◽  
Author(s):  
Aleksandar Perić ◽  
Jelena Sotirović ◽  
Cveta Špadijer-Mirković ◽  
Svjetlana Matković-Jožin ◽  
Aneta V. Perić ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Secretions
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