Diagnosing of bakers' respiratory allergy: Is specific inhalation challenge test essential?

2011 ◽  
Vol 32 (2) ◽  
pp. 111-118 ◽  
Author(s):  
Marta Wiszniewska ◽  
Ewa Nowakowska-Świrta ◽  
Cezary Pałczyński ◽  
Jolanta Walusiak-Skorupa
Keyword(s):  
Challenge Test ◽  
Respiratory Allergy ◽  
Specific Inhalation Challenge ◽  
Inhalation Challenge

Can persulfates cause hypersensitivity pneumonitis? A report of specific inhalation challenge test in 42 hairdressers

2020 ◽  
Author(s):  
Jens-Tore Granslo ◽  
Jorunn Kirkeleit ◽  
Stein Håkon Låstad Lygre ◽  
William Horsnell ◽  
Thomas Blix Grydeland ◽  
...  
Keyword(s):  
Hypersensitivity Pneumonitis ◽  
Challenge Test ◽  
Specific Inhalation Challenge ◽  
Inhalation Challenge

scholarly journals Can reactive airways dysfunction syndrome (RADS) transform into occupational asthma due to "sensitisation" to isocyanates?

Thorax ◽  
1998 ◽  
Vol 53 (2) ◽  
pp. 152-153 ◽  
Author(s):  
C Leroyer ◽  
L Perfetti ◽  
A Cartier ◽  
J L Malo
Keyword(s):  
Case History ◽  
Occupational Asthma ◽  
Challenge Test ◽  
Diphenylmethane Diisocyanate ◽  
Specific Inhalation Challenge ◽  
Inhalation Challenge ◽  
High Level ◽  
Reactive Airways

The case history is described of a worker who presented with a history suggestive of reactive airways dysfunction syndrome which occurred after an acute high level inhalation of diphenylmethane diisocyanate. Further exposure at work, at a time when concentrations of isocyanates were no longer "irritant", suggested occupational asthma; this diagnosis was confirmed by a specific inhalation challenge test.

Occupational asthma caused by peracetic acid-hydrogen peroxide mixture

2019 ◽  
Vol 69 (4) ◽  
pp. 294-297 ◽  
Author(s):  
G I Walters ◽  
P S Burge ◽  
V C Moore ◽  
M O Thomas ◽  
A S Robertson
Keyword(s):  
Hydrogen Peroxide ◽  
Peracetic Acid ◽  
Occupational Asthma ◽  
Challenge Test ◽  
City Hospital ◽  
Flow Measurements ◽  
Occupational Lung Disease ◽  
Specific Inhalation Challenge ◽  
Inhalation Challenge ◽  
The Uk

Abstract Background Healthcare practice in the UK has moved away from using aldehyde disinfectants for the decontamination of endoscopes, in part due to the risk of respiratory sensitization. Peracetic acid (PAA) in combination with hydrogen peroxide (HP) is a commonly used alternative. Aim We describe a case of occupational asthma (OA) diagnosed at our specialist occupational lung disease clinic and caused by occupational exposure to PAA-HP mixture, used as a disinfectant in an endoscope washer-disinfector machine. Case report A 48-year-old man employed as a mycologist and environmental microbiologist at a Birmingham city hospital, UK, presented following an acute exposure to PAA-HP mixture causing lacrimation, burning optic pain and headache. He had also experienced symptoms suggestive of OA for the preceding 10 months, and the diagnosis was confirmed through OASYS analysis of serial peak expiratory flow measurements. He had been exposed to PAA-HP mixture whilst working in the endoscopy department for 12 months prior to the acute episode, and a subsequent specific inhalation challenge test was positive with a late asthmatic response to PAA-HP mixture. Conclusion This case provides evidence for a sensitization mechanism in OA caused by PAA-HP mixture.

scholarly journals Pulmonary Function Testing in Work-Related Asthma: An Overview from Spirometry to Specific Inhalation Challenge

2021 ◽  
Vol 18 (5) ◽  
pp. 2325
Author(s):  
Mathias Poussel ◽  
Isabelle Thaon ◽  
Emmanuelle Penven ◽  
Angelica I. Tiotiu
Keyword(s):  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Objective Evaluation ◽  
Pulmonary Function Testing ◽  
Initial Assessment ◽  
Work Related ◽  
Specific Inhalation Challenge ◽  
Occupational Setting ◽  
Inhalation Challenge ◽  
Function Testing

Work-related asthma (WRA) is a very frequent condition in the occupational setting, and refers either to asthma induced (occupational asthma, OA) or worsened (work-exacerbated asthma, WEA) by exposure to allergens (or other sensitizing agents) or to irritant agents at work. Diagnosis of WRA is frequently missed and should take into account clinical features and objective evaluation of lung function. The aim of this overview on pulmonary function testing in the field of WRA is to summarize the different available tests that should be considered in order to accurately diagnose WRA. When WRA is suspected, initial assessment should be carried out with spirometry and bronchodilator responsiveness testing coupled with first-step bronchial provocation testing to assess non-specific bronchial hyper-responsiveness (NSBHR). Further investigations should then refer to specialists with specific functional respiratory tests aiming to consolidate WRA diagnosis and helping to differentiate OA from WEA. Serial peak expiratory flow (PEF) with calculation of the occupation asthma system (OASYS) score as well as serial NSBHR challenge during the working period compared to the off work period are highly informative in the management of WRA. Finally, specific inhalation challenge (SIC) is considered as the reference standard and represents the best way to confirm the specific cause of WRA. Overall, clinicians should be aware that all pulmonary function tests should be standardized in accordance with current guidelines.

Inhalation Challenge Test in the Diagnosis of Occupational Rhinitis

2008 ◽  
Vol 22 (1) ◽  
pp. 38-46 ◽  
Author(s):  
Liisa K. Airaksinen ◽  
Timo O. Tuomi ◽  
Matti O. Tuppurainen ◽  
Antti I. Lauerma ◽  
Elina M. Toskala
Keyword(s):  
Challenge Test ◽  
Occupational Rhinitis ◽  
Inhalation Challenge

Inhalation challenge test using pigeon eggs for chronic hypersensitivity pneumonitis

2020 ◽  
Vol 50 (12) ◽  
pp. 1381-1390
Author(s):  
Ryo Okuda ◽  
Tamiko Takemura ◽  
Yu Mikami ◽  
Eri Hagiwara ◽  
Tae Iwasawa ◽  
...  
Keyword(s):  
Hypersensitivity Pneumonitis ◽  
Challenge Test ◽  
Inhalation Challenge ◽  
Chronic Hypersensitivity Pneumonitis

Specific Inhalation Challenge in Persulfate Asthma

2015 ◽  
pp. 85-91 ◽  
Author(s):  
O. Hagemeyer ◽  
E. Marek ◽  
V. van Kampen ◽  
I. Sander ◽  
M. Raulf ◽  
...  
Keyword(s):  
Specific Inhalation Challenge ◽  
Inhalation Challenge
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