scholarly journals LEFT VENTRICULAR HYPERTROPHY DEVELOPMENT PREDICTORS IN PATIENTS WITH ESSENTIAL HYPERTENSION: ROLE OF PRO- AND ANTI-INFLAMMATORY CYTOKINES

2018 ◽  
Vol 0 (Ahead of Print) ◽  
Author(s):  
L. Tsoy ◽  
A. Polupanov ◽  
I. Sabirov ◽  
T. Zalova ◽  
F. Rysmatova
Keyword(s):  
Essential Hypertension ◽  
Left Ventricular Hypertrophy ◽  
Inflammatory Cytokines ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Anti Inflammatory

scholarly journals Predictors of left ventricular hypertrophy development in patients with essential hypertension: role of pro- and anti-inflammatory cytokines

2018 ◽  
Vol 2 (Issue 4) ◽  
pp. 97 ◽  
Author(s):  
Larisa Tsoi ◽  
Andrei Polupanov ◽  
Ibragim Sabirov ◽  
Tazagul Zalova ◽  
Flora Rysmatova
Keyword(s):  
Essential Hypertension ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Interleukin 10 ◽  
Left Ventricular ◽  
Myocardial Remodeling ◽  
Tnf Α ◽  
Factor Α ◽  
Necrosis Factor

Objective: The data on the relationship between the level of TNF-α and interleukin-10 with the presence of left ventricular hypertrophy and myocardial remodeling in patients with essential hypertension is presented. Methods: Overall, 156 patients with essential hypertension aged 40 to 75 years (with mean age 55.8 ± 7.5 years) were examined; of which 57 were women and 99 were men. All patients were divided into two groups. The first group included 73 patients showing the presence of  left ventricular hypertrophy (LVH), established by echocardiography; the second group included 83 patients who showed no signs of LVH on the echocardiogram. Results: According to the study, no relationship was found between the concentration of tumor necrosis factor α (TNF-α) and the development of LVH. It was also shown that only men, but not women with, were associated with the presence of LVH with low levels of interleukin-10 ( IL-10). In addition, a negative correlation was found between the concentration of tumor necrosis factor α (TNF-α) and IL-10 with the thickness of the left ventricular walls at the initial stages of myocardial remodeling on the echocardiography. Conclusion: Thus, our study demonstrates the modulating role of inflammation on the processes of myocardial remodeling in hypertension.

Role of Calcineurin-Dependent Signaling Pathway on the Left Ventricular Hypertrophy Induced by Pressure Overload

2001 ◽  
Vol 31 (11) ◽  
pp. 1159
Author(s):  
Hainan Piao ◽  
Jin Sook Kwon ◽  
Hye Young Lee ◽  
Tae Jin Youn ◽  
Dong Woon Kim ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Signaling Pathway ◽  
Ventricular Hypertrophy ◽  
Pressure Overload ◽  
Left Ventricular ◽  
Dependent Signaling Pathway

scholarly journals Cardiac Arrhythmias and Left Ventricular Hypertrophy in Dipper and Nondipper Patients With Essential Hypertension

2000 ◽  
Vol 64 (7) ◽  
pp. 499-504 ◽  
Author(s):  
Hiroshi Ijiri ◽  
Isao Kohno ◽  
DongFeng Yin ◽  
Hiroshi Iwasaki ◽  
Masahiro Takusagawa ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Left Ventricular Hypertrophy ◽  
Cardiac Arrhythmias ◽  
Ventricular Hypertrophy ◽  
Left Ventricular
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