scholarly journals Preclinical Evaluation of Sol-gel Synthesized Modulated 45S5-Bioglass Based Biodegradable Bone Graft Intended for Alveolar Bone Regeneration

2021 ◽  
Vol 30 (3) ◽  
pp. 303-308
Author(s):  
Nebu George Thomas ◽  
Anand Manoharan ◽  
Anand Anbarasu
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Alveolar Bone ◽  
Sol Gel ◽  
Preclinical Evaluation ◽  
45S5 Bioglass

scholarly journals Sol–gel processing of novel bioactive Mg-containing silicate scaffolds for alveolar bone regeneration

2015 ◽  
Vol 30 (6) ◽  
pp. 740-749 ◽  
Author(s):  
Ourania-Menti Goudouri ◽  
Caroline Vogel ◽  
Alina Grünewald ◽  
Rainer Detsch ◽  
Eleana Kontonasaki ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Alveolar Bone ◽  
Sol Gel ◽  
Gel Processing

scholarly journals Fabrication of Three-Dimensional Composite Scaffold for Simultaneous Alveolar Bone Regeneration in Dental Implant Installation

2020 ◽  
Vol 21 (5) ◽  
pp. 1863 ◽  
Author(s):  
Hun-Jin Jeong ◽  
So-Jung Gwak ◽  
Kyoung Duck Seo ◽  
SaYa Lee ◽  
Jeong-Ho Yun ◽  
...  
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Dental Implant ◽  
Alveolar Bone ◽  
Insertion Site ◽  
High Porosity ◽  
Hybrid Scaffold ◽  
Implant Surgery ◽  
3D Printed ◽  
Dental Implant Surgery

Dental implant surgeries involve the insertion of implant fixtures into alveolar bones to replace missing teeth. When the availability of alveolar bone at the surgical site is insufficient, bone graft particles are filled in the insertion site for successful bone reconstruction. Bone graft particles induce bone regeneration over several months at the insertion site. Subsequently, implant fixtures can be inserted at the recipient site. Thus, conventional dental implant surgery is performed in several steps, which in turn increases the treatment period and cost involved. Therefore, to reduce surgical time and minimize treatment costs, a novel hybrid scaffold filled with bone graft particles that could be combined with implant fixtures is proposed. This scaffold is composed of a three-dimensionally (3D) printed polycaprolactone (PCL) frame and osteoconductive ceramic materials such as hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP). Herein, we analyzed the porosity, internal microstructure, and hydrophilicity of the hybrid scaffold. Additionally, Saos-2 cells were used to assess cell viability and proliferation. Two types of control scaffolds were used (a 3D printed PCL frame and a hybrid scaffold without HA/β-TCP particles) for comparison, and the fabricated hybrid scaffold was verified to retain osteoconductive ceramic particles without losses. Moreover, the fabricated hybrid scaffold had high porosity and excellent microstructural interconnectivity. The in vitro Saos-2 cell experiments revealed superior cell proliferation and alkaline phosphatase assay results for the hybrid scaffold than the control scaffold. Hence, the proposed hybrid scaffold is a promising candidate for minimizing cost and duration of dental implant surgery.

Implant site preparation application of injectable platelet-rich fibrin for vertical and horizontal bone regeneration: A clinical report

2020 ◽  
Author(s):  
Prakan Thanasrisuebwong ◽  
Sirichai Kiattavorncharoen ◽  
George R Deeb ◽  
Sompop Bencharit
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Bone Defect ◽  
Alveolar Bone ◽  
Treatment Protocol ◽  
Biologically Active ◽  
Asian Woman ◽  
Clinical Report ◽  
Platelet Rich Fibrin ◽  
Implant Placement

Guided bone regeneration (GBR) using a combined injectable platelet-rich fibrin (i-PRF), leukocyte- and platelet-rich fibrin (L-PRF) and biocompatible bone substitute materials, is a convenient and effective method to augment a combined vertical and horizontal bone defect. This approach can create sufficient bone quality and quantity for implant surgical sites. A 55-year-old Asian woman presented with a severe bone defect in posterior mandible. The edentulous mandibular alveolar ridge was severely resorbed vertically and horizontally.  A GBR procedure using i-PRF and L-PRF combined with particulate bone graft was performed. Postoperative cone beam computed tomography scans, 8 months after the augmentation, revealed a large regeneration of the alveolar bone sufficient for implant placement. A combination i-PRF/L-PRF and particulate bone graft may provide biologically active molecules as well as a scaffold for osteogenesis. This treatment protocol may be a viable option for a large bone defect required augmentation prior to implant placement.

Tooth Derived Bone Graft Material

2016 ◽  
Vol 7 (1) ◽  
pp. 32-35 ◽  
Author(s):  
Kalyana Chakravarthy Pentapati ◽  
Komal Smriti ◽  
Chayanika Bhattacharjya ◽  
Srikanth Gadicherla ◽  
Abhay Taranath Kamath
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Bone Grafting ◽  
Alveolar Bone ◽  
Autogenous Bone ◽  
Graft Material ◽  
Bone Graft Material ◽  
Dentin Matrix ◽  
Demineralized Dentin Matrix ◽  
Demineralized Dentin

ABSTRACT Alveolar bone deficiency is a major postoperative complication in the treatment of traumatic injuries, periodontal diseases and likewise. Hence, alveolar bone repair remains a major hurdle in tissue engineering. Autogenous bone can be wellthought- of as benchmark for bone grafting sans its limitations and complications. In order to overcome these limitations, there is an increased demand of bone graft materials that led to numerous studies on different techniques and materials for bone regeneration over the years. Dentin and bone having same biochemical similarities led to the idea of using it as a bone regenerative material. Demineralized dentin matrix (DDM), an organic material obtained from dentin has been shown to possess osteogenic capacity. Demineralized dentin matrix may prosper in future endodontic world as an apexification material and as a permanent root canal filling material as well. Quick in bone forming as compared to conventional bone graft, this material is a boon to the dental world in this era. This manuscript reviews various studies on different types of DDM as a bone grafting material, and also summarizes the suggested pathway of bone regeneration. How to cite this article Bhattacharjya C, Gadicherla S, Kamath AT, Smriti K, Pentapati KC. Tooth Derived Bone Graft Material. World J Dent 2016;7(1):32-35.

Application of BMP-2 for bone graft in Dentistry

RSBO ◽  
2016 ◽  
Vol 12 (1) ◽  
pp. 88
Author(s):  
Lídia Audrey Rocha Valadas Marques ◽  
Edvan Alves da Costa Júnior ◽  
Mara Assef Leitão Lotif ◽  
Edilson Martins Rodrigues Neto ◽  
Francisco Filipe Carvalho da Silva ◽  
...  
Keyword(s):  
Life Expectancy ◽  
Bone Graft ◽  
Bone Regeneration ◽  
Tooth Loss ◽  
Clinical Use ◽  
Increase Life Expectancy ◽  
Bone Replacement ◽  
Morphogenetic Protein ◽  
The Face ◽  
Global Increase

Introduction: The global increase life expectancy and the resulting tooth loss has required searching for new rehabilitation alternatives in Dentistry. Biomaterials can be defined as any material that acts replacing a lost bone defect and its function. In Dentistry, many studies have aimed to improve bone regeneration through the use of BMPs for bone replacement. Objective: To review the literature on the use and clinical viability of human morphogenetic protein for the jaws reconstruction. Material and methods: The following databases were searched: Pubmed, Bireme, Lilacs, and Scielo and 30 articles published between 1965 and 2013 were found using the following descriptors: “dental implants”, “maxillary sinus”, and “biocompatible materials”. Results: Several studies demonstrate the biological advantages of rhBMP-2 on bone regeneration of the jaws. In recent years, morphogenetic protein has presented a large clinical use. Conclusion: Despite being a high-cost biomaterial, rhBMP-2 is a viable and very effective alternative for reconstruction of defects of the face.

scholarly journals Alveolar bone graft with Platelet Rich Plasma in cleft alveolus

2013 ◽  
Vol 3 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Chandan Gupta ◽  
Divya Mehrotra ◽  
Shadab Mohammad ◽  
Vaibhav Khanna ◽  
Gulshan Kumar Singh ◽  
...  
Keyword(s):  
Bone Graft ◽  
Alveolar Bone ◽  
Platelet Rich Plasma
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