Peculiar Aspects of Reading and Writing Performances in Patients with Olivopontocerebellar Atrophy

2002 ◽  
Vol 94 (2) ◽  
pp. 677-694 ◽  
Author(s):  
Rita Moretti ◽  
Paola Torre ◽  
Rodolfo M. Antonello ◽  
Nicola Carraro ◽  
Sandro Zambito-Marsala ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Movement Control ◽  
Control Group ◽  
Olivopontocerebellar Atrophy ◽  
Reading And Writing ◽  
High Incidence ◽  
Ocular Movement ◽  
Reticular System ◽  
Conscious Process

Olivopontocerebellar atrophy (OPCA) is a still debated condition, of which motor disruption is the most common feature. A high incidence of associated mood disorders may exist, but there are few studies on concomitant cognitive impairment. Our aim was to assess whether there is reading and writing disruption in olivopontocerebellar atrophy (OPCA). 6 patients were administered different reading and writing tasks. Scores were then compared to those obtained by healthy volunteers. There was an evident impairment in reading and writing execution in out patients compared to those of the control group. On the contrary, no difference could be found in abstraction, problem-solving, and memory tasks. We discuss the results, debating the role of the cerebellum in the conscious process of cognition or in ocular movement control (necessary for reading and writing fluidity and effective execution) and in the dynamic activation of all the cerebral cortex mediated by the diffuse projection to the reticular system.

scholarly journals Forensic implications of rape

2006 ◽  
Vol 59 (11-12) ◽  
pp. 567-571 ◽  
Author(s):  
Milan Novakovic
Keyword(s):  
Bosnia And Herzegovina ◽  
Criminal Law ◽  
Control Group ◽  
Sexual Assaults ◽  
Physical Strength ◽  
Young Males ◽  
High Incidence ◽  
High Level ◽  
And Behavior

Introduction. Rape is a sexual act of violence in which physical strength is used. Criminal law imposes strict punishments for such crimes as rape. Psycho-pathologically, rape is among the gravest of crimes, often associated with extremely deviated behavior. This article deals with the forensic aspects of sexual violence in Bosnia and Herzegovina in the period from 2000-2004. We report about sexual assaults, personality of delinquents, motives and consequences of rape. Material and Methods. Two groups of violent offenders were compared in the study: perpetrators of rape (N=90), and perpetrators of other criminal offences (N=90-recidivists). The control group included young males (N=90). Results. The results of the study show a high level of violence in Bosnia and Herzegovina. The rape rate equals the level of homicide in Bosnia and Herzegovina. Rape offenders are mostly people with personal disorders (70%), but they also present with other illnesses and behavior disorders. Conclusion. The significance of rape as a violent crime has not been sufficiently studied. High incidence of violence and rape in Bosnia and Herzegovina is extremely disturbing. The most disturbing aspect is the increase of violence and failure to take certain measures. The role of psychiatry is to provide penal education, treatment and programs for elimination of consequences of rape. .

scholarly journals Association ofTNF-857C>T,TNFRSF1A36A>G, andTNFRSF1B676T>GPolymorphisms with Ischemic Stroke in a Greek Population

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Sofia Markoula ◽  
Anthoula Chatzikyriakidou ◽  
Sotirios Giannopoulos ◽  
Kargiotis Odysseas ◽  
Sofia Markou ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Patient Group ◽  
Large Scale ◽  
Genetic Factors ◽  
Predisposing Factors ◽  
Greek Population ◽  
Control Group ◽  
High Incidence

Background. The role of genetic factors in the predisposition to develop ischemic stroke has been assessed by previous studies. The main goal of the current study was to determine any possible role ofTNF-857C>T,TNFRSF1A36A>G,andTNFRSF1B676T>Gpolymorphisms in risk for stroke.Materials and Methods. One hundred seventy-three patients with first ever ischemic stroke of solely atherosclerotic etiology in Northwest Greece and a control group of 179 healthy unrelated subjects were evaluated.Results.TNFα-857TT,TNFR136AA, andTNFR2676TTgenotypes were significantly increased in the patient group compared to controls (, OR = 2.47 (1.26–4.84), , OR = 1.97 (1.22–3.17), and , OR = 2.2 (1.43–3.37), resp.). In addition, theTNFR136Aand theTNFR2676Talleles were found significantly increased in patients compared to controls (, OR = 1.48 (1.1–2) and , OR = 1.75 (1.25–2.46), resp.).Conclusion. The high incidence of these genotypes and alleles in patient group suggests that they are potentially predisposing factors for stroke in the Greek population studied. Large-scale multicenter controlled studies are needed to verify these polymorphisms effects on stroke susceptibility.

scholarly journals The role of intestinal microbiote disorders in the pathogenesis of psoriasis and eczema infectious

2018 ◽  
pp. 92-97
Author(s):  
T. A. Lytynska ◽  
T. Р. Korgova
Keyword(s):  
Clinical Course ◽  
Gallstone Disease ◽  
Control Group ◽  
Functional Disorders ◽  
High Incidence ◽  
Microbiological Examination ◽  
Pathogenetic Factor ◽  
Irritable Bowel ◽  
The Impact

The purpose of the work was to study the quantitative and qualitative composition of microbiota of the colon in patients with psoriasis and eczema infectious and to analyze the impact of its violations on the severity of the clinical course of the diseases. There were examined in a complex way 34 patients with psoriasis and eczema in factious illness. The age of the subjectsrangedfrom 23 to 70 years, amongthem: women – 15 (44,1 %), men – 19 (55,9 %), the period of the disease ranged from 2 to 42 years. The control group consisted of 20 practically healthy persons. In order to diagnose concomitant dysbiotic changes in the large intestine, microbiological examination of feces was performed on the patients (according to the method of Epstein – Litvak and Vilshanskaya). A high incidence of various intestinal pathologies (dyspepsia, gastroesophageal reflux disease, irritable bowel syndrome, functional disorders by the hepatobiliary system, gallstone disease etc.) was detected. In the microbiological study of feces, concomitant dysbiosis of the colon was detected in 16 (72,7 %) patients. Disturbance of the microbiota of the colon of varying severity is more often diagnosed in patients with more severe clinical course of psoriasis and eczema of infectious, as well as with a longer duration of the disease. The obtained data suggest that the intestinal microbiota, in particular colon dysbiosis, should be considered an important pathogenetic factor that negatively influences the nature and severity of the psoriasis and infectious eczema and requires timely diagnosis and appropriate medical correction.

scholarly journals The role of intestinal microbiote disorders in the pathogenesis of psoriasis and eczema infectious

2018 ◽  
pp. 92-97
Author(s):  
T. A. Lytynska ◽  
T. Р. Korgova
Keyword(s):  
Clinical Course ◽  
Gallstone Disease ◽  
Control Group ◽  
Functional Disorders ◽  
High Incidence ◽  
Microbiological Examination ◽  
Pathogenetic Factor ◽  
Irritable Bowel ◽  
The Impact

The purpose of the work was to study the quantitative and qualitative composition of microbiota of the colon in patients with psoriasis and eczema infectious and to analyze the impact of its violations on the severity of the clinical course of the diseases. There were examined in a complex way 34 patients with psoriasis and eczema in factious illness. The age of the subjectsrangedfrom 23 to 70 years, amongthem: women – 15 (44,1 %), men – 19 (55,9 %), the period of the disease ranged from 2 to 42 years. The control group consisted of 20 practically healthy persons. In order to diagnose concomitant dysbiotic changes in the large intestine, microbiological examination of feces was performed on the patients (according to the method of Epstein – Litvak and Vilshanskaya). A high incidence of various intestinal pathologies (dyspepsia, gastroesophageal reflux disease, irritable bowel syndrome, functional disorders by the hepatobiliary system, gallstone disease etc.) was detected. In the microbiological study of feces, concomitant dysbiosis of the colon was detected in 16 (72,7 %) patients. Disturbance of the microbiota of the colon of varying severity is more often diagnosed in patients with more severe clinical course of psoriasis and eczema of infectious, as well as with a longer duration of the disease. The obtained data suggest that the intestinal microbiota, in particular colon dysbiosis, should be considered an important pathogenetic factor that negatively influences the nature and severity of the psoriasis and infectious eczema and requires timely diagnosis and appropriate medical correction.

scholarly journals The role of arterial hypertension in the natural course of cerebral aneurysms

1998 ◽  
Vol XXX (1-2) ◽  
pp. 15-18
Author(s):  
Е. R. Lebedeva ◽  
V. Р. Sakovich
Keyword(s):  
Arterial Hypertension ◽  
Cerebral Aneurysms ◽  
Natural Course ◽  
Control Group ◽  
Early Age ◽  
Genetic Origin ◽  
Threefold Increase ◽  
High Incidence ◽  
History Of

Arterial hypertension (AH) incidence has been analyzed in 61 patients with aneurysms of cerebral vessels and its enfluence on its natural course. In most patients (57 people) aneurysms were accompanied by intracranial hemorrhage; 4 patients did not show ruptures of aneurysms. Arterial hypertension incidence in patients with aneurysms made up 62,3 %, in control group - 50%. In conditions of AH presence threefold increase of incidence of recurrent early hemorrhage was shown, as well as rupture of aneurysms in early age and aggravating of neurologic symptomatology. In 4 patients rupture of small aneurysmatic diverticula took place. In family history of patients with aneurysms relatively high incidence of AH was marked, as compared with the control group. Questions of AH genetic origin in aneurysmous patients were discussed, and its role in natural course of aneurysms.

Tryptophan-Niacin Metabolism in Rat with Puromycin Aminonucleoside-Induced Nephrosis

2006 ◽  
Vol 76 (1) ◽  
pp. 28-33 ◽  
Author(s):  
Yukari Egashira ◽  
Shin Nagaki ◽  
Hiroo Sanada
Keyword(s):  
Body Weight ◽  
Urinary Excretion ◽  
Enzyme Activities ◽  
Treated Group ◽  
Control Group ◽  
Puromycin Aminonucleoside ◽  
Low Level ◽  
Key Enzyme

We investigated the change of tryptophan-niacin metabolism in rats with puromycin aminonucleoside PAN-induced nephrosis, the mechanisms responsible for their change of urinary excretion of nicotinamide and its metabolites, and the role of the kidney in tryptophan-niacin conversion. PAN-treated rats were intraperitoneally injected once with a 1.0% (w/v) solution of PAN at a dose of 100 mg/kg body weight. The collection of 24-hour urine was conducted 8 days after PAN injection. Daily urinary excretion of nicotinamide and its metabolites, liver and blood NAD, and key enzyme activities of tryptophan-niacin metabolism were determined. In PAN-treated rats, the sum of urinary excretion of nicotinamide and its metabolites was significantly lower compared with controls. The kidneyα-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) activity in the PAN-treated group was significantly decreased by 50%, compared with the control group. Although kidney ACMSD activity was reduced, the conversion of tryptophan to niacin tended to be lower in the PAN-treated rats. A decrease in urinary excretion of niacin and the conversion of tryptophan to niacin in nephrotic rats may contribute to a low level of blood tryptophan. The role of kidney ACMSD activity may be minimal concerning tryptophan-niacin conversion under this experimental condition.

The Use of Posterior Pericardiotomy Technique to Prevent Postoperative Pericardial Effusion in Cardiac Surgery

2012 ◽  
Vol 15 (2) ◽  
pp. 84 ◽  
Author(s):  
Canturk Cakalagaoglu ◽  
Cengiz Koksal ◽  
Ayse Baysal ◽  
Gokhan Alici ◽  
Birol Ozkan ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Heart Surgery ◽  
Artery Bypass ◽  
Pericardial Tamponade ◽  
Anxiety Level ◽  
Control Group ◽  
Echocardiographic Study ◽  
Number Of Patients ◽  
Hospital Stays

<p><b>Aim:</b> The goal was to determine the effectiveness of the posterior pericardiotomy technique in preventing the development of early and late pericardial effusions (PEs) and to determine the role of anxiety level for the detection of late pericardial tamponade (PT).</p><p><b>Materials and Methods:</b> We divided 100 patients randomly into 2 groups, the posterior pericardiotomy group (n = 50) and the control group (n = 50). All patients undergoing coronary artery bypass grafting surgery (CABG), valvular heart surgery, or combined valvular and CABG surgeries were included. The posterior pericardiotomy technique was performed in the first group of 50 patients. Evaluations completed preoperatively, postoperatively on day 1, before discharge, and on postoperative days 5 and 30 included electrocardiographic study, chest radiography, echocardiographic study, and evaluation of the patient's anxiety level. Postoperative causes of morbidity and durations of intensive care unit and hospital stays were recorded.</p><p><b>Results:</b> The 2 groups were not significantly different with respect to demographic and operative data (<i>P</i> > .05). Echocardiography evaluations revealed no significant differences between the groups preoperatively; however, before discharge the control group had a significantly higher number of patients with moderate, large, and very large PEs compared with the pericardiotomy group (<i>P</i> < .01). There were 6 cases of late PT in the control group, whereas there were none in the pericardiotomy group (<i>P</i> < .05). Before discharge and on postoperative day 15, the patients in the pericardiotomy group showed significant improvement in anxiety levels (<i>P</i> = .03 and .004, respectively). No differences in postoperative complications were observed between the 2 groups.</p><p><b>Conclusion:</b> Pericardiotomy is a simple, safe, and effective method for reducing the incidence of PE and late PT after cardiac surgery. It also has the potential to provide a better quality of life.</p>

The Estimation of prostate specific antigen (PSA) concentrations in patients with prostatitis by fully automated ELISA technique.

2020 ◽  
Vol 3 (11) ◽  
pp. 1100-1104
Author(s):  
Hussein Naeem Aldhaheri ◽  
Ihsan Edan AlSaimary ◽  
Murtadha Mohammed ALMusafer
Keyword(s):  
Personal Information ◽  
Receptor Gene ◽  
Specific Antigen ◽  
Gene Clusters ◽  
Control Group ◽  
P Value ◽  
Group Data ◽  
Elisa Technique ◽  
And Control

      The Aim of this study was to determine Immunogenetic expression of  Toll-like receptor gene clusters related to prostatitis, to give acknowledge about Role of TLR in prostatitis immunity in men from Basrah and Maysan provinces. A case–control study included 135 confirmed prostatitis patients And 50 persons as a control group. Data about age, marital status, working, infertility, family history and personal information like (Infection, Allergy, Steroid therapy, Residency, Smoking, Alcohol Drinking, Blood group, Body max index (BMI) and the clinical finding for all patients of Prostatitis were collected. This study shows the effect of PSA level in patients with prostatitis and control group, with P-value <0.0001 therefore the study shows a positive significant between elevated PSA levels and Prostatitis.

THE ROLE OF LITERACY METHODS IN MASTERING OF WRITTEN LANGUAGE BY STUDENTS WITH DEVELOPMENTAL DYSLEXIA

2019 ◽  
Vol 7 (1) ◽  
pp. 10-18
Author(s):  
Tsvetanka Tsenova
Keyword(s):  
Experimental Work ◽  
Developmental Dyslexia ◽  
Reading Skills ◽  
Writing Skills ◽  
Written Language ◽  
Reading And Writing ◽  
Empirical Verification ◽  
Literacy Methods ◽  
The Relationship

This article focuses on the relationship between literacy methods applied at school and the emergence of serious difficulties in mastering reading and writing skills that shape the developmental dyslexia. The problem was analyzed theoretically and subjected to empirical verification. Experimental work was presented which aims to study the phonological and global reading skills of 4- th grade students with and without dyslexia. Better global reading skills have been demonstrated in all tested children, and this is much more pronounced in those with dyslexia than their peers without disorders. Hence, the need to develop a special, corrective methodology for literacy of students with developmental dyslexia consistent with their psychopathological characteristics.

Effectiveness Of Toilet Training Education On Mother's Behavior And Toddler Age Toilet Training Ability (18-36 Months)

2020 ◽  
Vol 5 (2) ◽  
pp. 49-55
Author(s):  
Hafiko Andresni ◽  
Zahtamal Zahtamal ◽  
Winda Septiani ◽  
Mitra Mitra ◽  
Lita Lita
Keyword(s):  
Sampling Technique ◽  
T Test ◽  
The Body ◽  
Toilet Training ◽  
Wilcoxon Test ◽  
Control Group ◽  
Maternal Knowledge ◽  
Control Group Design ◽  
Significant Difference

ABSTRACT Toilet training is an effort to train children to be able to control and urinate (BAK) and defecate (BAB). Toilet training is one of the main tasks of children at toddler age. Toilet training is one of the main tasks of children in toddler age which is very important to be done to create independence in children in controlling BAK and BAB and children know the parts of the body and their functions. Data in 2012 shows that ± 60% of parents do not teach toilet training to children from an early age. The aim of the study was to find out the effectiveness of toilet training education on maternal behavior and toilet skills in toddler age training (18-36 months). The study was conducted in July-August 2018. This type of quantitative research used the design of the Quasy pretest and posttest experiment with non-equivalent control group design. Samples were 36 mothers and 36 children with purposive sampling technique. Data analysis used Paired t test, Wilcoxon test, Man-Whitney test an Independent t test. The results showed that toilet training education through lecture methods, modules and maze games was more effective than toilet training education through lecture and leaflet methods on children's knowledge and abilities. Conversely, for the role of mothers in supervision there is no significant difference in effectiveness. Health education is recommended in health promotion programs to increase maternal knowledge, the role of mothers and the ability of toilet training children independently. Keywords: Toilet training, Lecture method, Module, Maze game, Leaflet, Knowledge, Role of mother, Children's ability.

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