Fatigue microdamage in the radial predilection site for osteosarcoma in dogs

2002 ◽  
Vol 63 (6) ◽  
pp. 896-899 ◽  
Author(s):  
Kelly L. Gellasch ◽  
Vicki L. Kalscheur ◽  
Murray K. Clayton ◽  
Peter Muir
Keyword(s):  
Predilection Site ◽  
Fatigue Microdamage

The Effect of Number of Cycles on Microdamage Accumulation in Bovine Trabecular Bone

2001 ◽  
Author(s):  
Tara L. Arthur Moore ◽  
Lorna J. Gibson
Keyword(s):  
Trabecular Bone ◽  
Bone Remodeling ◽  
Low Cycle Fatigue ◽  
Cycle Fatigue ◽  
Repetitive Motion ◽  
Microdamage Accumulation ◽  
Lower Load ◽  
Small Cracks ◽  
Number Of Cycles ◽  
Fatigue Microdamage

Abstract Microdamage, in the form of small cracks, exists in healthy bone. Microdamage can be created by an overload or by repetitive motion (fatigue) during daily activities. Usually, microdamage is repaired during bone remodeling and a steady state is maintained. However, in cases of excessive microdamage creation or slowed bone remodeling, microdamage can coalesce to create a fracture. Our previous work [1,2] has investigated microdamage accumulation with increasing strain in bovine trabecular bone loaded in monotonic compression and compressive fatigue. Specimens fatigued at relatively high load levels fail after a few loading cycles, while specimens fatigued at lower load levels may undergo thousands of cycles before failure. During high cycle fatigue, microdamage may accumulate by the growth of pre-existing microcracks, as well as by the crack initiation seen in low cycle fatigue.

The distribution of Nippostrongylus brasiliensis in prolonged infections in lactating and neonatally infected rats

Parasitology ◽  
1974 ◽  
Vol 68 (3) ◽  
pp. 347-354 ◽  
Author(s):  
R. M. Connan
Keyword(s):  
Post Infection ◽  
Nippostrongylus Brasiliensis ◽  
Active Response ◽  
Predilection Site

In lactating rats examined 3 weeks post infection, adult Nippostrongylus brasiliensis were found in the duodenum close to the pylorus. Worms migrated from the predilection site, shown by Brambell (1965) and Alphey (1970) to be approximately 25% down the intestine, during the second week of infection. A similar migration took place in neonatally infected rats.It was suggested that the migration was an active response to immunological damage. It could be prevented by early betamethasone treatment but only modified by treatment given late in infection.

Influence of infection intensity on predilection sites in swine trichinellosis

1999 ◽  
Vol 73 (3) ◽  
pp. 251-254 ◽  
Author(s):  
F.J. Serrano ◽  
J.E. Pérez-Martín ◽  
D. Reina ◽  
I. Navarrete ◽  
C.M.O. Kapel
Keyword(s):  
Host Species ◽  
Trichinella Spiralis ◽  
Infection Intensity ◽  
Intensity Of Infection ◽  
Wild Boars ◽  
Predilection Site

The muscular distribution of Trichinella spiralis or T. britovi was studied by digestion in 59 experimentally infected pigs and seven wild boars. Crus muscle was the predilection site in 89.3% of 28 heavily infected swine with 146–3634 larvae per gram (lpg), but in 51.6% of middle to light infections (0.005–59 lpg) the basis of the tongue showed higher larval densities than the crus muscle. The basis of the tongue was also the predilection site in 71.4% of wild boars. Highest counts in other muscles were found only in lightly infected pigs. The influence of intensity of infection, host species, and Trichinella species on muscle distribution is discussed.

Contrast-enhanced micro-computed tomography of fatigue microdamage accumulation in human cortical bone

Bone ◽  
2011 ◽  
Vol 48 (3) ◽  
pp. 443-450 ◽  
Author(s):  
Matthew D. Landrigan ◽  
Jiliang Li ◽  
Travis L. Turnbull ◽  
David B. Burr ◽  
Glen L. Niebur ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cortical Bone ◽  
Micro Computed Tomography ◽  
Human Cortical Bone ◽  
Contrast Enhanced ◽  
Microdamage Accumulation ◽  
Fatigue Microdamage

Fatigue Microdamage in Bovine Trabecular Bone

2003 ◽  
Vol 125 (6) ◽  
pp. 769-776 ◽  
Author(s):  
Tara L. A. Moore ◽  
Lorna J. Gibson
Keyword(s):  
Trabecular Bone ◽  
Compressive Strain ◽  
Staining Technique ◽  
Area Fraction ◽  
Maximum Strain ◽  
Yield Strain ◽  
Fluorochrome Staining ◽  
Microdamage Accumulation ◽  
Small Cracks ◽  
Fatigue Microdamage

Microdamage, in the form of small cracks, may accumulate in trabecular bone loaded in fatigue. Specimens of bovine trabecular bone were loaded in compressive fatigue at one of four normalized stresses and loading was stopped after the specimens reached one of six maximum strains. Microdamage was identified using a fluorochrome staining technique, and microdamage parameters, including the number of damaged trabeculae and the damaged area fraction, were measured. No microdamage was observed during loading to strains below the yield strain; at higher strains, all microdamage parameters increased with increasing maximum compressive strain. Few significant differences were observed in the type or amount of microdamage accumulation between specimens loaded to the same maximum strain at different normalized stresses; however, more trabecular fractures were observed at high numbers of cycles, which corresponded to low normalized stresses.

scholarly journals Congenital Epulis: A Two-Case Report

2021 ◽  
pp. 336-340
Author(s):  
Monica Ivanov ◽  
Bianca Stroe ◽  
Valeriu Ardeleanu ◽  
Razvan Hainarosie ◽  
Vlad Constantin ◽  
...  
Keyword(s):  
Benign Tumor ◽  
Prenatal Period ◽  
Second Trimester ◽  
Clinical Appearance ◽  
Multidisciplinary Assessment ◽  
Predilection Site ◽  
Rare Benign Tumor ◽  
Congenital Epulis ◽  
Oral Tumors ◽  
Tentative Diagnosis

Congenital epulis is a rare benign tumor of the newborn that could be detected in the prenatal period. Females are more often affected than males and the premaxillary region is usually the predilection site for this oral mass. Excision is the treatment of choice and no recurrences have been reported so far. We present our experience with two cases of congenital epulis, detected in the second trimester of gestation and treated shortly after birth with no further complications. Histopathology should differentiate between congenital epulis and other congenital oral tumors even if its clinical appearance is usually enough to make a tentative diagnosis. A multidisciplinary assessment in the management of this tumor can avoid unwanted complications such as airway obstruction or bleeding.

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