scholarly journals Diarrhoea and Associated Clinical Features in Different Pathotypes of Diarrheagenic E. coliIsolated in Children: A Case-Control Study in a Tertiary Care Hospital

2021 ◽  
Vol 53 (03) ◽  
pp. 250-258
Author(s):  
Tapas Ranjan Behera ◽  
Keyword(s):  
Clinical Features ◽  
Case Control Study ◽  
Case Control ◽  
Watery Diarrhoea ◽  
Correct Identification ◽  
Care Hospital ◽  
Age Group ◽  
Major Health Problem ◽  
Childhood Diarrhoea ◽  
Control Study

Background: Acute gastroenteritis remains to be a major health problem in children causing high morbidity and mortalityIn India, diarrhoea is the third most common cause of death in children younger than 5 years of age, with an estimation of 300,000 deaths each year. Diarrheagenic Escherichia coli (DEC) being one of the important bacterial agents, the present hospital-based study was done to enlighten on the occurrence of different pathotypes and clinical features associated with DEC related diarrhoea. Methods:The case-control study was carried out in SCB Medical College, Odisha from October 2014 to September 2016 on the childhood diarrhoea cases (≤ 14 years of age). Stool samples were collected and processed to isolate the causative bacterial agent by standard biochemical test, serotyping and multiplex PCR. Results: 350 cases and 100 controls were included in the study. The different pathotypes of DEC were isolated significantly more in cases than control group (P value = 0.0205) with an isolation rate of 7.4% in cases. 12 (46.2%) of DEC were in 0-1 year age group followed by 1-5 year of age group i.e. 11 (42.3%) and least in 5-14 years of age group i.e. 3 (11.5%). The most common pathotype was Enterotoxigenic E. coli (ETEC) followed by Enteropathogenic E.coli (EPEC). Fever is the most common symptom associated with DEC diarrhoea; the other two common symptoms were watery diarrhoea and vomiting. Exclusive breastfeeding was the protective factor. Seasonal variation of DEC was found more among the cases in the rainy season. Conclusion: Different pathotypes of DEC being associated commonly with childhood diarrhoea, the correct identification of various types of DEC along with the clinical knowledge is important to reduce the morbidity and mortality caused by it.

scholarly journals Iron deficiency in febrile seizures: a prospective case control study

2020 ◽  
Vol 7 (12) ◽  
pp. 2267
Author(s):  
Vasanth N. Kumar ◽  
Farogh Hassan ◽  
Lata Jha ◽  
Abnish Kumar ◽  
Chandreyi Bandopadhyay ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Ferritin ◽  
Mean Corpuscular Volume ◽  
Case Control Study ◽  
Febrile Seizures ◽  
Case Control ◽  
Care Hospital ◽  
Age Group ◽  
Corpuscular Volume ◽  
Control Study

Background: The objective of the study was to evaluate the role of iron deficiency in febrile seizures.Methods: Case control study conducted at Pediatric department of Tertiary care hospital. A total 70 cases and 70 controls were included in the study. Consecutive cases and controls were selected. Cases were children of age group 6 months to 5 years with simple febrile seizures and controls were children of same age group with short febrile illness without any seizures. After consent, detailed history was taken and clinical examination were carried out for both groups. Blood investigations were done to diagnose iron deficiency in both cases and controls. Iron deficiency was diagnosed as per WHO criteria haemoglobin <11 g/dl in cases <5 years mean corpuscular volume<70 fl, mean corpuscular haemoglobin <27 pg and serum ferritin<30 microgram/dl.Results: Mean corpuscular volume was less than 70 fl/ml in 51% cases and 31% controls and mean corpuscular hemoglobin was less than 27 pg/ml in 84% cases and 40% of controls indicating statistically significant association of MCV and MCH between cases and controls .Serum ferritin was less than 30 ng/ml in 44% in cases as compared to 26% of controls, there was statistically significant difference between serum ferritin levels in cases and controls. From the above findings, study showed statistically significant association between iron deficiency anaemia and febrile seizures (p value <0.01; OR- 8.05 (3.6-17.93) (df-1).Conclusions: Iron deficiency is a major risk factor for simple febrile seizures in age group of 6 months to 60 months.

Risk factors for development of dehydration in children aged under five who have acute watery diarrhoea: a case-control study

Public Health ◽  
1998 ◽  
Vol 112 (4) ◽  
pp. 233-236
Author(s):  
S P Zodpey ◽  
S G Deshpande ◽  
S N Ughade ◽  
A V Hinge ◽  
S N Shrikhande
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Watery Diarrhoea ◽  
Under Five ◽  
Control Study

Clinical Features and Related Factors of Poststroke Pathological Laughing and Crying: A Case–Control Study

2016 ◽  
Vol 25 (3) ◽  
pp. 556-564 ◽  
Author(s):  
Geying Wang ◽  
Fei Teng ◽  
Yuhui Chen ◽  
Yuanhua Liu ◽  
Yancheng Li ◽  
...  
Keyword(s):  
Clinical Features ◽  
Case Control Study ◽  
Case Control ◽  
Related Factors ◽  
Control Study

scholarly journals 717. Antibiotic treatment of Shiga toxin-producing Escherichia coli related gastroenteritis and the risk of hemolytic uremic syndrome: a population based matched case-control study in Japan

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S409-S410
Author(s):  
Shota Myojin ◽  
Kyongsun Pak ◽  
Mayumi Sako ◽  
Tohru Kobayashi ◽  
Takuri Takahashi ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Shiga Toxin ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Population Based ◽  
Case Control ◽  
Age Group ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

Abstract Background The role of therapeutic intervention, particularly antibiotics, for Shiga toxin-producing Escherichia coli (STEC) related infection is controversial. Methods We performed a population based matched case-control study to assess the association between treatment (antibiotics, antidiarrheal agents and probiotics) for STEC related infections and HUS development. We identified all STEC HUS patients as cases and matched five non-HUS patients as controls using the data from the National Epidemiological Surveillance of Infectious Diseases (NESID) between January 1, 2017, and December 31, 2018. Further medical information was obtained by standardized questionnaires answered by physicians who registered each patient. We used multivariate conditional logistic regression model to evaluate the association between exposures (use of antibiotics, use of antidiarrheal agents, days between disease onset and fosfomycin administration [within two or three days]) and the development of HUS, by matched odds ratios (OR) and 95% confidence intervals (CI). Covariates we used were sex, age group, area code, presence of diarrhea and other factors. We also performed subgroup analyses using age (adults and children) as a stratification factor. Results 7,760 STEC related patients were registered in the NESID. We selected patients who had a record of HUS diagnosis (n=182) and matched controls without HUS (n=910). After collecting standardized paper-based questionnaires, we enrolled 90 HUS patients and 371 non-HUS patients for analysis. In the main analysis, matched OR of fosfomycin was 0.75(0.47-1.20) in all ages, 1.41(0.51-3.88) in adults and 0.58(0.34-1.01) in children. Matched OR of antidiarrheal agents was 2.07(1.07-4.03) in all ages, 1.84(0.32-10.53) in adults, 2.65(1.21-5.82) in children. Matched OR of probiotics was 0.86(0.46-1.61) in all ages, 0.76(0.21-2.71) in adults, 1.00(0.48-2.09) in children. There was no significant association between the timing of fosfomycin use in the first two or five days of illness and HUS development in any age group. Conclusion Our results suggest that fosfomycin might decrease the risk of HUS in children younger than 15 years of age with STEC confirmed bacterial gastroenteritis. Disclosures All Authors: No reported disclosures

scholarly journals QT Interval Changes in Children With Febrile Convulsion Comparing With Healthy

2021 ◽  
pp. 1-15
Author(s):  
Alireza Teimouri ◽  
◽  
Noor Mohammad Noori ◽  
Ali Khajeh ◽  
◽  
...  
Keyword(s):  
Qt Interval ◽  
Case Control Study ◽  
Age Groups ◽  
Febrile Convulsion ◽  
Case Control ◽  
Healthy Children ◽  
Age Group ◽  
Chi Square ◽  
Pediatric Cardiologist ◽  
Control Study

A temperature-related seizure is a febrile seizure that affects the QT interval. The purpose of this study was to evaluate the changes in the QT interval caused by febrile convulsion compared with healthy children. Method This case-control study considered the distribution of 180 children equally shared between patients and controls. The study was conducted at the "Ali Ebne Abi Talib" Hospital in Zahedan, Iran. The disease diagnosed and confirmed based on standard definitions of febrile convulsion. QT interval measured by ECG and interpreted by a pediatric cardiologist and collected data were analyzed with SPSS 19 considering 0.05 as significant error. Results Among the ECG parameters, HR, R in aVL, S in V3, LVM, QTd, QTc and QTcd were significantly different in children with febrile convulsion compared to the peers. From those who had abnormal QTd, FC children were more frequented but not significant (CHI SQUARE=1.053, p=0.248), when children with FC were more in abnormality regarding QTc (CHI SQUARE=13.032, p<0.001) and QTcd (CHI SQUARE=21.6, P<0.001) significantly. In children with FC, those who were aged less than 12 months, had the highest level of HR but not significant (CHI SQUARE=4.59, p=0.101). Similar trends occurred for R in aVL and S in V3 that were higher in the age group >24 months (p>0.05). LVM had the highest value in the age group of >24 months significantly (CHI SQUARE= 52.674, P<0.001) and the other QT parameters were same in Fc children with different age groups (P>0.05). Conclusion From the study concluded that dispersion corrected QT, corrected QT and dispersion QT changed significantly in children with febrile convulsion in comparing with the healthy children but with constant values in children with FC in different age groups.

scholarly journals HACEK infective endocarditis: Epidemiology, clinical features, and outcome: A case–control study

2018 ◽  
Vol 76 ◽  
pp. 120-125 ◽  
Author(s):  
Juan Ambrosioni ◽  
Clara Martinez-Garcia ◽  
Jaume Llopis ◽  
Cristina Garcia-de-la-Maria ◽  
Marta Hernández-Meneses ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Clinical Features ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Effects of COVID ‐19 on Parkinson's Disease Clinical Features: A Community‐Based Case‐Control Study

2020 ◽  
Vol 35 (8) ◽  
pp. 1287-1292 ◽  
Author(s):  
Roberto Cilia ◽  
Salvatore Bonvegna ◽  
Giulia Straccia ◽  
Nico Golfrè Andreasi ◽  
Antonio E. Elia ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Features ◽  
Case Control Study ◽  
Case Control ◽  
Community Based ◽  
Control Study

The effect of age, sex and clinical features on the volume of Corpus Callosum in pre-schoolers with Autism Spectrum Disorder: a case-control study

2017 ◽  
Vol 47 (6) ◽  
pp. 568-578 ◽  
Author(s):  
Alessia Giuliano ◽  
Irene Saviozzi ◽  
Paolo Brambilla ◽  
Filippo Muratori ◽  
Alessandra Retico ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Corpus Callosum ◽  
Clinical Features ◽  
Case Control Study ◽  
Autism Spectrum ◽  
Case Control ◽  
Spectrum Disorder ◽  
Effect Of Age ◽  
Control Study
Sign in / Sign up

Export Citation Format

Share Document