scholarly journals Prevalence of Hepatitis B, C, and D among Thalassemia patients in Sulaimani Governorate

2017 ◽  
Vol 2 (2) ◽  
pp. 137-142
Author(s):  
Salih Ahmed Hama ◽  
Moaid Ibrahim Sawa
Keyword(s):  
Hepatitis B ◽  
Socioeconomic Development ◽  
Risk Groups ◽  
Confirmatory Test ◽  
Public Health Issue ◽  
Enzyme Linked Immunosorbent Assay ◽  
Hcv Prevalence ◽  
Hbv Prevalence ◽  
Recombinant Immunoblot Assay ◽  
Elisa Technique

Infectious diseases are the leading cause of mortality worldwide, with hepatitis viruses in particular making global impact on socioeconomic development and this infection remains a serious public health issue. This study was performed to investigate the prevalence of Hepatitis B, C and D among multi-transfused risk groups in Sulaimani Governorate, 120 major thalassemic patients were tested by serological and enzyme-linked immunosorbent assay (ELISA) technique and Recombinant ImmunoBlot Assay (RIBA) test was done as a confirmatory test for all HCV ELISA positive patients. It was observed that the prevalence of HCV was higher (29.1%) comparing to HBV (22.5%) and HDV (3.3%). The prevalence of HCV-HBV coinfection was (5%), HCV-HBV-HDV coinfections were (0.83%). Statistical analysis showed that the age was significantly effective on the prevalence of HBV (p = 0.009), parenteral medication users showed a significant relation with HBV and HCV prevalence (p = 0.03 and 0.041) respectively. The blood transfusion frequency was significantly related to HBV and HCV prevalence (p = 0.042 and 0.035) respectively. It was noticed that vaccination significantly related to HBV prevalence among thalassemic patients (p = 0.002).

scholarly journals Current prevalence of chronic hepatitis B and C virus infection in the general population, blood donors and pregnant women in the EU/EEA: a systematic review

2017 ◽  
Vol 145 (14) ◽  
pp. 2873-2885 ◽  
Author(s):  
S. H. I. HOFSTRAAT ◽  
A. M. FALLA ◽  
E. F. DUFFELL ◽  
S. J. M. HAHNÉ ◽  
A. J. AMATO-GAUCI ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chronic Hepatitis ◽  
General Population ◽  
Hepatitis B ◽  
Pregnant Women ◽  
Blood Donors ◽  
Population Estimates ◽  
Hcv Prevalence ◽  
Hbv Prevalence ◽  
The Eu

SUMMARYThis systematic review aimed at estimating chronic hepatitis B (HBV) and C virus (HCV) prevalence in the European Union (EU) and Economic Area (EEA) countries in the general population, blood donors and pregnant women. We searched PubMed©, Embase© and Cochrane Library databases for reports on HBV and HCV prevalence in the general population and pregnant women in EU/EEA countries published between 2005 and 2015. Council of Europe data were used for HBV and HCV blood donor prevalence. HBV general population estimates were available for 13 countries, ranging from 0·1% to 4·4%. HCV general population estimates were available for 13 countries, ranging from 0·1% to 5·9%. Based on general population and blood donor estimates, the overall HBV prevalence in the EU/EEA is estimated to be 0·9% (95% CI 0·7–1·2), corresponding to almost 4·7 million HBsAg-positive cases; and the overall HCV prevalence to be 1·1% (95% CI 0·9–1·4), equalling 5·6 million anti-HCV-positive cases. We found wide variation in HCV and HBV prevalence across EU/EEA countries for which estimates were available, as well as variability between groups often considered a proxy for the general population. Prevalence estimates are essential to inform policymaking and public health practice. Comparing to other regions globally, HBV and HCV prevalence in the EU/EEA is low.

scholarly journals Human hydatidosis: an under discussed occupational zoonosis in India

2013 ◽  
Vol 50 (2) ◽  
pp. 87-90 ◽  
Author(s):  
B. Singh ◽  
G. Singh ◽  
R. Sharma ◽  
J. Sharma ◽  
R. Aulakh ◽  
...  
Keyword(s):  
Risk Groups ◽  
Public Health Issue ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Serum Samples ◽  
Dairy Farmers ◽  
Future Studies ◽  
The Status ◽  
Group Population ◽  
And Control

AbstractHuman hydatidosis is an important public health issue in India and many other developing countries. There is lack of data related to occurrence of this disease in certain risk groups. The present study was therefore designed to assess the seroprevalence of human hydatidosis among occupational risk groups in Punjab (India). One hundred and forty nine human serum samples from dog handlers, veterinarians/para veterinarians, dairy farmers, patients with liver disorders, HIV positives and control group (visiting hospital for other problems) were collected and analyzed using a commercially available enzyme linked immunosorbent assay (ELISA). The results revealed that 23 (15.43 %) subjects were seropositive for human hydatidosis. High seropositivity were recorded in dog handlers (30 %), followed by the other risk group populations. Relative risk of being infected was found to be 4.80 times high in dog handlers when compared to control group population. Future studies must be planned to determine the significance of these findings and the status of human hydatidosis in India.

scholarly journals Trends of hepatitis B notification rates in Turkey, 1990 to 2012

2013 ◽  
Vol 18 (47) ◽  
Author(s):  
P Ay ◽  
M A Torunoglu ◽  
S Com ◽  
Z Çipil ◽  
S Mollahaliloğlu ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Socioeconomic Development ◽  
Control Strategies ◽  
Horizontal Transmission ◽  
Immunisation Programme ◽  
Risk Groups ◽  
Prevention Measures ◽  
National Immunisation Programme ◽  
Catch Up ◽  
The Impact

Turkey is a country with intermediate endemicity for hepatitis B, and approximately 4% of the population are HBsAg-positive. A number of measures have been implemented to prevent hepatitis B infection. In 1998, hepatitis B antigen was included in the national immunisation programme, and infants have since been vaccinated with three doses. Catch-up strategies, vaccination for high risk groups and screening measures were also adopted. The aim of this study was to evaluate the impact of the prevention and control strategies on hepatitis B notification rates in Turkey in the period from 1990 to 2012, using data from the national surveillance system. Secular trends revealed that rates showed an initial increasing trend, followed by a steady decline from 2005. The most dramatic decline occurred among children younger than 15 years, highlighting the benefits of vaccination and catch-up strategies. However, vaccination cannot fully explain the decrease in this age group. Socioeconomic development, through interrupting the horizontal transmission may also have contributed. After 2005, a steady decline was achieved also among those 15 years and older. The rates in adults were higher, which indicates that stronger prevention measures are needed to target this group, particularly men.

scholarly journals Current Challenges in Hepatitis B

2011 ◽  
Vol 19 (1) ◽  
pp. 38-44
Author(s):  
MA Ahad ◽  
MA Alim
Keyword(s):  
Public Health ◽  
Liver Disease ◽  
Hepatitis B ◽  
World Wide ◽  
Public Health Issue ◽  
Mortality And Morbidity ◽  
Hbv Prevalence ◽  
Prevention And Treatment ◽  
Significant Public Health ◽  
Causes Of Mortality

Viral hepatitis and its sequelae is one of the important causes of mortality and morbidity world wide. Hepatitis B is a major cause of chronic liver disease and a significant public health issue. Between 350 million to 400 million people world wide chronically infected with HBV. The HBV prevalence in Bangladesh is 2.3 to 9.7 % with an approximate carrier of 10 million. The prevention and treatment of hepatitis B possess a great challenge.   doi: 10.3329/taj.v19i1.3168 TAJ 2006; 19(1): 38-44

scholarly journals Seroprevalence of hepatitis B and hepatitis C in people who inject drugs and other high risk groups in a tertiary care hospital in Northeast India

2017 ◽  
Vol 4 (9) ◽  
pp. 3306 ◽  
Author(s):  
Arup Roy ◽  
Praveen Sh ◽  
Kh Sulochana Devi ◽  
Paotinlal Haokip ◽  
Gracy Laldinmawii ◽  
...  
Keyword(s):  
Hepatitis C ◽  
High Risk ◽  
Hepatitis B ◽  
People Who Inject Drugs ◽  
Risk Groups ◽  
Unprotected Sex ◽  
Current Status ◽  
Enzyme Linked Immunosorbent Assay ◽  
Care Hospital ◽  
High Risk Populations

Background: Viral hepatitis is a serious public health problem affecting billions of people globally. The Hepatitis B virus (HBV) and Hepatitis C virus (HCV) are blood borne pathogens, frequently causing deaths among general and various high risk populations. This study was carried out with the aim to determine the seroprevalence of HBV and HCV in people who inject drugs (PWID) and other risk groups. Methods: A cross-sectional study carried out in the Dept. of Microbiology, RIMS, Imphal from October 2014 to September 2016. 103 high risk individuals, including PWID, spouse of high risk people, unprotected sex with female sex worker (FSW), multiple partners (MP), men having sex with men (MSM) and needle prick injuries were included in this study. Serum samples were tested using Enzyme linked immunosorbent assay (ELISA). Results: Out of 103 cases, 87.4% were males and 12.6% females. PWID comprised of 49.5%. Seroprevalence of HBV was 17.4%, anti HBc IgG 16.5% and anti HBc IgM 0.9%. Seroprevalence of HCV was 41.7%, anti HCV IgG 39.8% and anti HCV IgM 1.9%. The rate of HBV and HCV coinfection was 9.7%. Among the PWID seroprevalence of HBV and HCV was 17.6% and 64.7% respectively. Conclusions: This study determines the current status of acute and chronic infection with HBV and HCV in high risk populations. Anti HBc IgG & IgM and anti HCV IgG and IgM are sensitive epidemiological markers to determine the burden of the disease. 

scholarly journals Epidemiology of Hepatitis B Virus Infection in Bangladesh: Prevalence among General Population, Risk Groups and Genotype Distribution

Genes ◽  
2018 ◽  
Vol 9 (11) ◽  
pp. 541 ◽  
Author(s):  
Md. uz-Zaman ◽  
Ayesha Rahman ◽  
Mahmuda Yasmin
Keyword(s):  
Hepatitis B Virus ◽  
General Population ◽  
Hepatitis B ◽  
Horizontal Transmission ◽  
Risk Groups ◽  
Hbv Infection ◽  
Present Review ◽  
Genotype Distribution ◽  
B Virus ◽  
Hbv Prevalence

Despite a considerable body of published research on hepatitis B in Bangladesh, researchers continue to lament the lack of reliable information about hepatitis B virus (HBV) infection epidemiology. The present review aims to provide a comprehensive survey of the literature with particular focus on a number of epidemiological questions, as well as a commentary on the trends of hepatitis B research as it has taken place in Bangladesh. The key themes to emerge from this review are: first, beyond noting a declining trend, it is difficult to provide conclusive estimates about HBV prevalence in the general population of Bangladesh. The majority of the studies, even the ones conducted on apparently healthy populations, fail to be adequately representative for the reasons explored in the article. Secondly, HBV infection in Bangladesh is sharply stratified across sociodemographic lines, which speaks to the role of awareness and risk exposure in HBV prevalence. Third, more research on occult infection rates is required to estimate the extent of risk posed by the current blood donation screening program, which relies exclusively on hepatitis B surface antigen as a biomarker. The same considerations apply for the comparative importance of vertical versus horizontal transmission and prevalence among particular risk groups like healthcare workers with high occupational exposure. Finally, while recent studies do allow us, albeit with some ambiguity, to draw conclusions about distribution of HBV genotypes in Bangladesh, there needs to be an added emphasis on molecular epidemiology. It is hoped that the present review, the first of its kind in Bangladesh, will serve as an up-to-date summary of the course HBV epidemiology research in Bangladesh has taken thus far, as well as crucial gaps to address going forward.

D-Dimer Determination to Exclude Pulmonary Embolism: a Two-Step Approach Using Latex Assay as a Screening Tool

1994 ◽  
Vol 72 (01) ◽  
pp. 089-091 ◽  
Author(s):  
P de Moerloose ◽  
Ph Minazio ◽  
G Reber ◽  
A Perrier ◽  
H Bounameaux
Keyword(s):  
Pulmonary Embolism ◽  
Screening Tool ◽  
Screening Tests ◽  
Enzyme Linked Immunosorbent Assay ◽  
Elisa Assay ◽  
Elisa Technique ◽  
Diagnostic Step ◽  
D Dimer ◽  
Rule Out ◽  
Latex Test

SummaryD-dimer (DD), when measured by a quantitative enzyme-linked immunosorbent assay (ELISA), is a valuable test to exclude venous thromboembolism (VTE). However, DD ELISA technique is not appropriate for emergency use and the available agglutination latex assays are not sensitive enough to be used as an alternative to rule out the diagnosis of VTE. Latex assays could still be used as screening tests. We tested this hypothesis by comparing DD levels measured by ELISA and latex assays in 334 patients suspected of pulmonary embolism. All but one patient with a positive (DD ≥500 ng/ml) latex assay had DD levels higher than 500 ng/ml with the ELISA assay. Accordingly, ELISA technique could be restricted to patients with a negative result in latex assay. This two-step approach would have spared about 50% of ELISA in our cohort. In conclusion, our data indicate that a latex test can be used as a first diagnostic step to rule out pulmonary embolism provided a negative result is confirmed by ELISA and the performance of the latex assay used has been assessed properly.

scholarly journals Epidemiological Characteristics of Carrying Viral Hepatitis B Antigen in the Population of the Nišava District

2014 ◽  
Vol 31 (2) ◽  
pp. 121-128
Author(s):  
Marina Kostić ◽  
Biljana Kocić ◽  
Nataša Rančić
Keyword(s):  
Hepatitis B ◽  
Health Care Providers ◽  
Urban Areas ◽  
Drug Users ◽  
Risk Groups ◽  
Epidemiological Surveillance ◽  
Annual Reports ◽  
Care Providers ◽  
Upward Trend ◽  
Epidemiological Characteristics

Summary The aim of this paper was to determine the trend of diseases and epidemiological characteristics of viral antigen carrying of hepatitis B for better implementation of prevention and control of the disease activity. The annual reports, reports of diseases - deaths from infectious diseases, epidemiological survey of the Public Health Institute (IPH) Niš were used as the material. The period from 2002 to 2011 in the Nišava District was considered. A descriptive method was used. HBsAg carrying shows an upward trend (y=15+3.27 x). Most carriers are males (57.27%), live in urban areas (98.16/ 100.000 population), average age 41.92 years old ±SD 18.59, pensioners (22.42%). 54.05% are nephrology patients (almost all retirees under the age of 60 years old). Only 15.76% were hospitalized. The data on the vaccination status are insufficient. In 5.45%, co-infection with hepatitis C virus was found. 63.33% belong to the group of patients for whom there were no data on the mode of transmission. Hemodialysis patients make 16.67%, blood donors 9.39%, 6.36% pregnant women and injecting drug users 1.21%. The upward trend of carrying, the presence of all known risk groups in the population of carrying in the Nišava District points to the need for improved epidemiological surveillance, strict application of protective measures, conducting of statutory vaccination of all categories of people exposed to particular risk of infection as well as continuing education on preventive measures of both population and health care providers.

scholarly journals Contribution of HIV/AIDS-Related Human and Social Sciences Research to a Better Understanding of the Challenges of Hepatitis B Prevention, Diagnosis and Care

2021 ◽  
Vol 9 (6) ◽  
pp. 1166
Author(s):  
Charlotte Bauquier ◽  
Marie Préau
Keyword(s):  
Social Sciences ◽  
Hepatitis B ◽  
Retention In Care ◽  
World Health ◽  
Public Health Issue ◽  
Human And Social Sciences ◽  
Virus Research ◽  
Screening And Prevention ◽  
Hepatitis B Prevention ◽  
Hiv Aids

Recent scientific advances in hepatitis B virus research hint at the possibility of finding a cure in the medium term. In this context, the characterization of infected persons constitutes a major public health issue in terms of implementing adapted screening and prevention strategies. Overcoming the current challenges national health systems face in hepatitis B diagnosis is essential if the World Health Organization’s target of treating 80% of infected patients by 2030 is to be reached. These challenges reflect those previously faced in the fight against HIV/AIDS. Using the knowledge produced to date in Human and Social Sciences research in the fight against HIV/AIDS, we propose avenues of reflection to support and guide the development of research in the diagnosis of hepatitis B infection. More specifically, we present theoretical, methodological and epistemological considerations for how HSS research can be optimized in the following three HBV diagnosis-related areas: (i) access to screening; (ii) retention in care; and (iii) the integration of quality of life measurement in clinical trials.

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