scholarly journals Erythrocyte n-6 Polyunsaturated Fatty Acids, Gut Microbiota, and Incident Type 2 Diabetes: A Prospective Cohort Study

Diabetes Care ◽  
2020 ◽  
Vol 43 (10) ◽  
pp. 2435-2443 ◽  
Author(s):  
Zelei Miao ◽  
Jie-sheng Lin ◽  
Yingying Mao ◽  
Geng-dong Chen ◽  
Fang-fang Zeng ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Fatty Acids ◽  
Cohort Study ◽  
Gut Microbiota ◽  
Polyunsaturated Fatty Acids ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Incident Type ◽  
Incident Type 2 Diabetes

[beta]eta-hydroxybutyrate and risk for incident type 2 diabetes: results from the prevend prospective cohort study

2019 ◽  
Author(s):  
Jose L Flores-Guerrero ◽  
Margery A Connelly ◽  
Dion Groothof ◽  
Eke G Gruppen ◽  
Stephan JL Bakker ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Incident Type ◽  
Incident Type 2 Diabetes

scholarly journals Serum Levels of Apolipoproteins and Incident Type 2 Diabetes: A Prospective Cohort Study

Diabetes Care ◽  
2016 ◽  
Vol 40 (3) ◽  
pp. 346-351 ◽  
Author(s):  
Adela Brahimaj ◽  
Symen Ligthart ◽  
M. Arfan Ikram ◽  
Albert Hofman ◽  
Oscar H. Franco ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Serum Levels ◽  
Incident Type ◽  
Incident Type 2 Diabetes

scholarly journals Periodontitis and incident type 2 diabetes: a prospective cohort study

2017 ◽  
Vol 44 (3) ◽  
pp. 266-274 ◽  
Author(s):  
Lewis Winning ◽  
Christopher C. Patterson ◽  
Charlotte E. Neville ◽  
Frank Kee ◽  
Gerard J. Linden
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Incident Type ◽  
Incident Type 2 Diabetes

scholarly journals Spousal diabetes status as a risk factor for incident type 2 diabetes: a prospective cohort study and meta-analysis

2019 ◽  
Vol 56 (6) ◽  
pp. 619-629 ◽  
Author(s):  
Duke Appiah ◽  
Pamela J. Schreiner ◽  
Elizabeth Selvin ◽  
Ellen W. Demerath ◽  
James S. Pankow
Keyword(s):  
Type 2 Diabetes ◽  
Risk Factor ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Incident Type ◽  
Diabetes Status ◽  
Incident Type 2 Diabetes

scholarly journals Trans Fatty Acid Biomarkers and Incident Type 2 Diabetes: Pooled Analysis from 10 Prospective Cohort Studies in the Fatty Acids and Outcome Research Consortium (FORCE) (OR33-02-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Heidi Lai ◽  
Fumiaki Imamura ◽  
Andres Ardisson Korat ◽  
Rachel Murphy ◽  
Nathan Tintle ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Fatty Acids ◽  
Prospective Cohort ◽  
Pooled Analysis ◽  
Adjusted Relative Risk ◽  
Total Plasma ◽  
Incident Type ◽  
Incident Type 2 Diabetes ◽  
Average Maximum

Abstract Objectives To assess prospective association between circulating biomarkers of individual trans fatty acids (TFAs) and incident type 2 diabetes (T2D) in diverse populations. Methods A harmonized analysis of individual level data was conducted for TFA biomarkers and incident T2D by pooling ten prospective cohort or nested-case-control studies from five countries (Australia, Germany, Iceland, UK, and USA). Fatty acids (FAs) were measured in plasma phospholipid, red blood cell membrane phospholipid, or total plasma collected between 1990–2008 from 22,711 participants aged ≥18 years without prevalent diabetes. Evaluated TFAs included trans-16:1n-9, sum of trans-18:1 isomers (trans-18:1n6 to trans-18:1n12), sum of trans-18:2 isomers (cis/trans-18:2, trans/cis-18:2, trans/trans-18:2), and individual trans-18:2 isomers. The multivariable-adjusted relative risk or odds ratio was estimated in each cohort by lipid compartments using a pre-specified protocol for definitions of exposures, covariates, and outcomes for statistical analysis. Association estimates were pooled using fixed-effects inverse-variance weighted meta-analysis. Results During an average maximum of 14 years of follow-up, 2244 cases of incident T2D were identified. Median levels of TFAs across cohorts were 0.05–0.18% total FAs for trans-16:1n-9, 0.09–2.05% for total trans-18:1, 0.10–0.73% for total trans-18:2, and 0.01–0.36% for individual trans-18:2 isomers. In overall pooled analysis, TFAs evaluated per inter-quintile range were not significantly associated with risk of T2D (Figure 1). Findings were consistent when TFAs were assessed categorically in study specific-quintiles, and when associations were pooled within lipid compartment (i.e., phospholipids vs. total plasma). Conclusions Overall, biomarker levels of TFAs were not significantly associated with risk of incident T2D in this international pooling project. Findings may be due to mixed TFA sources (industrial vs. ruminant), a general decline in TFA exposure during this period, or no effect of circulating TFA on diabetes. Associations of TFA biomarkers with T2D at higher exposures should be investigated. Funding Sources See Table 1. Supporting Tables, Images and/or Graphs

scholarly journals Change in fasting plasma glucose and incident type 2 diabetes mellitus: results from a prospective cohort study

BMJ Open ◽  
2016 ◽  
Vol 6 (5) ◽  
pp. e010889 ◽  
Author(s):  
Amirhossein Mozaffary ◽  
Samaneh Asgari ◽  
Maryam Tohidi ◽  
Sara Kazempour-Ardebili ◽  
Fereidoun Azizi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cohort Study ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Prospective Cohort ◽  
Incident Type ◽  
Incident Type 2 Diabetes
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