scholarly journals Early Detection of Hypoglycemia in Type 1 Diabetes Using Heart Rate Variability Measured by a Wearable Device

Diabetes Care ◽  
2019 ◽  
Vol 42 (4) ◽  
pp. 689-692 ◽  
Author(s):  
Marleen Olde Bekkink ◽  
Mats Koeneman ◽  
Bastiaan E. de Galan ◽  
Sebastian J. Bredie
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Early Detection ◽  
Wearable Device

Heart rate variability and circadian variations in type 1 diabetes mellitus

2006 ◽  
Vol 7 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Firat Kardelen ◽  
Gayaz Akcurin ◽  
Halil Ertug ◽  
Sema Akcurin ◽  
Iffet Bircan
Keyword(s):  
Diabetes Mellitus ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Circadian Variations

scholarly journals Rapid glucose rise reduces heart rate variability in adults with type 1 diabetes: A prospective secondary outcome analysis

2021 ◽  
Author(s):  
Max L. Eckstein ◽  
Othmar Moser ◽  
Norbert J. Tripolt ◽  
Peter N. Pferschy ◽  
Anna A. M. Obermayer ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Secondary Outcome ◽  
Outcome Analysis

scholarly journals Effects of Metformin Added to Insulin in Adolescents with Type 1 Diabetes: An Exploratory Crossover Randomized Trial

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Daizhi Yang ◽  
Jinhua Yan ◽  
Hongrong Deng ◽  
Xubin Yang ◽  
Sihui Luo ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Insulin Sensitivity ◽  
Body Mass ◽  
Autonomic Function ◽  
Insulin Dose ◽  
Glucose Variability

Background. To comprehensively assess the effects of metformin added to insulin on metabolic control, insulin sensitivity, and cardiovascular autonomic function in adolescents with type 1 diabetes. Materials and Methods. This was an exploratory, crossover, randomized trial conducted in adolescents with type 1 diabetes aged 12-18 years old. Participants were randomly received metformin (≤1000 mg/d) added to insulin for 24 weeks followed by insulin monotherapy for a subsequent 24 weeks or vice versa. Blood pressure, body mass index, insulin dose, estimated insulin sensitivity, glycated hemoglobin A1c (HbA1c), and lipid profiles were measured, with a 72-hour continuous glucose monitoring and 24-hour Holter monitoring performed at baseline, 24, and 50 weeks for the assessments of glucose variability and heart rate variability. Results. Seventeen patients with mean ± SD age 14.4 ± 2.3   years , body mass index 18.17 ± 1.81   kg / m 2 , median (IQR) diabetes duration 4.50 (3.58, 6.92) years, and HbA1c 9.0% (8.5%, 9.4%) were enrolled. The between-group difference in HbA1c of 0.28% (95% CI -0.39 to 0.95%) was not significant ( P = 0.40 ). Changes in body mass index, insulin dose, blood pressure, lipid profiles, and estimated insulin sensitivity were similar for metformin add-on vs. insulin monotherapy. Glucose variability also did not differ. Compared with insulin monotherapy, metformin add-on significantly increased multiple heart rate variability parameters. Conclusions. Metformin added to insulin did not improve metabolic control or glucose variability in lean/normal-weight adolescents with type 1 diabetes. However, metformin added to insulin significantly increased heart rate variability, suggesting that metformin might improve cardiovascular autonomic function in this population.

Heart Rate Variability During Cardiorespiratory Exercise Test in Type 1 Diabetes

2017 ◽  
pp. 181-184
Author(s):  
Mika P. Tarvainen ◽  
Sami Nikkonen ◽  
Juha E. Peltonen ◽  
Jyrki M. Aho ◽  
Anne S. Koponen ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Exercise Test

scholarly journals Impaired awareness of hypoglycemia is associated with progressive loss of heart rate variability in patients with type 1 diabetes

2015 ◽  
Vol 7 (Suppl 1) ◽  
pp. A63 ◽  
Author(s):  
Ticiana da Silva ◽  
Luiz Rolim ◽  
Celso de Camargo Sallum Filho ◽  
Livia M Zimmermann ◽  
Fernando Malerbi ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Progressive Loss ◽  
Impaired Awareness

scholarly journals Heart rate variability in children with type 1 diabetes mellitus

2014 ◽  
Vol 32 (2) ◽  
pp. 279-285 ◽  
Author(s):  
Camila Balsamo Gardim ◽  
Bruno Affonso P. de Oliveira ◽  
Aline Fernanda B. Bernardo ◽  
Rayana Loch Gomes ◽  
Francis Lopes Pacagnelli ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Nervous System ◽  
Type 1 Diabetes Mellitus ◽  
Parasympathetic Nervous System ◽  
Vagal Activity ◽  
Mesh Terms

OBJECTIVE:To gather current information about the effects of type 1 diabetes mellitus on children's cardiac autonomic behavior.DATA SOURCES: The search of articles was conducted on PubMed, Ibecs, Medline, Cochrane, Lilacs, SciELO and PEDro databases using the MeSH terms: "autonomic nervous system", "diabetes mellitus", "child", "type 1 diabetes mellitus", "sympathetic nervous system" and "parasympathetic nervous system", and their respective versions in Portuguese (DeCS). Articles published from January 2003 to February 2013 that enrolled children with 9-12 years old with type 1 diabetes mellitus were included in the review.DATA SYNTHESIS: The electronic search resulted in four articles that approached the heart rate variability in children with type 1 diabetes mellitus, showing that, in general, these children present decreased global heart rate variability and vagal activity. The practice of physical activity promoted benefits for these individuals.CONCLUSIONS: Children with type 1 diabetes mellitus present changes on autonomic modulation, indicating the need for early attention to avoid future complications in this group.

scholarly journals Impact of Glycemic Control on Heart Rate Variability in Youth with Type 1 Diabetes: The SEARCH CVD Study

2013 ◽  
Vol 15 (12) ◽  
pp. 977-983 ◽  
Author(s):  
Mamta Jaiswal ◽  
Tasha E. Fingerlin ◽  
Elaine M. Urbina ◽  
R. Paul Wadwa ◽  
Jennifer W. Talton ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Glycemic Control

scholarly journals Influence of Type 1 Diabetes on the Symbolic Analysis and Complexity of Heart Rate Variability in Young Adults

2018 ◽  
Author(s):  
Elaine Aparecida de Oliveira ◽  
Anne Kastelianne França da Silva ◽  
Diego Giuliano Destro Christofaro ◽  
Laís Manata Vanzella ◽  
Rayana Loch Gomes ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Young Adults ◽  
Symbolic Analysis

scholarly journals In amateur athletes with type 1 diabetes, a 9-day period of cycling at moderate-to-vigorous intensity unexpectedly increased the time spent in hyperglycemia, which was associated with impairment in heart rate variability

2020 ◽  
Author(s):  
Elodie Lespagnol ◽  
Olivia Bocock ◽  
Joris Heyman ◽  
François-Xavier Gamelin ◽  
Serge Berthoin ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Glycemic Variability ◽  
Amateur Athletes ◽  
Positive Effects ◽  
Vigorous Intensity ◽  
Exercise Induced ◽  
The Impact

<b>Objective</b> <p>In type 1 diabetes, autonomic dysfunction may occur early as a decrease in heart rate variability (HRV). In nondiabetic populations, the positive effects of exercise training on HRV are well documented. However, exercise in individuals with type 1 diabetes, particularly if strenuous and prolonged, can lead to sharp glycemic variations, which can negatively impact HRV. This study explores the impact of a 9-day cycling tour on HRV in this population, with a focus on exercise-induced glycemic excursions<i>.</i></p> <p><b>Research Design and Methods</b></p> <p>Twenty amateur athletes with uncomplicated type 1 diabetes cycled 1500km. HRV and glycemic variability were measured by heart rate and continuous glucose monitoring. Linear mixed models were used to test the effects of exercise on HRV, considering concomitant glycemic excursions and subject characteristics as covariates.</p> <p><b>Results</b></p> <p>Nighttime HRV tended to decrease with the daily distance traveled. The more time the subjects spent in hyperglycemia, the lower the parasympathetic tone was. This result is striking given that hyperglycemic excursions progressively increased throughout the 9 days of the tour, and to a greater degree on the days a longer distance was traveled, while time spent in hypoglycemia surprisingly decreased. This phenomenon occurred despite no changes in insulin administration and a decrease in carbohydrate intake from snacks. </p> <p><b>Conclusions</b></p> <p><a>In sports enthusiasts with type 1 diabetes</a>, multiday prolonged exercise at moderate-to-vigorous intensity worsened hyperglycemia with the latter being negatively associated with parasympathetic cardiac tone. Considering the putative deleterious consequences on cardiac risks, future work should focus on understanding and managing exercise-induced hyperglycemia.</p>

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