Efficacy and Safety of LixiLan, a Titratable Fixed-Ratio Combination of Insulin Glargine Plus Lixisenatide in Type 2 Diabetes Inadequately Controlled on Basal Insulin and Metformin: The LixiLan-L Randomized Trial

Vanita R. Aroda; Julio Rosenstock; Carol Wysham; Jeffrey Unger; Diego Bellido; Guillermo González-Gálvez; Akane Takami; Hailing Guo; Elisabeth Niemoeller; Elisabeth Souhami; Richard M. Bergenstal

doi:10.2337/dc16-1495

Efficacy and Safety of LixiLan, a Titratable Fixed-Ratio Combination of Insulin Glargine Plus Lixisenatide in Type 2 Diabetes Inadequately Controlled on Basal Insulin and Metformin: The LixiLan-L Randomized Trial

Diabetes Care ◽

10.2337/dc16-1495 ◽

2016 ◽

Vol 39 (11) ◽

pp. 1972-1980 ◽

Cited By ~ 104

Author(s):

Vanita R. Aroda ◽

Julio Rosenstock ◽

Carol Wysham ◽

Jeffrey Unger ◽

Diego Bellido ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Randomized Trial ◽

Basal Insulin ◽

Fixed Ratio ◽

Efficacy And Safety

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Erratum. Efficacy and Safety of LixiLan, a Titratable Fixed-Ratio Combination of Insulin Glargine Plus Lixisenatide in Type 2 Diabetes Inadequately Controlled on Basal Insulin and Metformin: The LixiLan-L Randomized Trial. Diabetes Care 2016;39:1972–1980

Diabetes Care ◽

10.2337/dc17-er06d ◽

2017 ◽

Vol 40 (6) ◽

pp. 809.2-809

Author(s):

Vanita R. Aroda ◽

Julio Rosenstock ◽

Carol Wysham ◽

Jeffrey Unger ◽

Diego Bellido ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Randomized Trial ◽

Diabetes Care ◽

Basal Insulin ◽

Fixed Ratio ◽

Efficacy And Safety

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Efficacy and Safety of LixiLan, a Titratable Fixed-Ratio Combination of Lixisenatide and Insulin Glargine, Versus Insulin Glargine in Type 2 Diabetes Inadequately Controlled on Metformin Monotherapy: The LixiLan Proof-of-Concept Randomized Trial

Diabetes Care ◽

10.2337/dc16-0046 ◽

2016 ◽

Vol 39 (9) ◽

pp. 1579-1586 ◽

Cited By ~ 51

Author(s):

Julio Rosenstock ◽

Michaela Diamant ◽

Vanita R. Aroda ◽

Louise Silvestre ◽

Elisabeth Souhami ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Randomized Trial ◽

Fixed Ratio ◽

Proof Of Concept ◽

Efficacy And Safety ◽

Metformin Monotherapy

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Efficacy and safety of basal insulin glargine 12 and 24 weeks after initiation in persons with type 2 diabetes: A pooled analysis of data from treatment arms of 15 treat-to-target randomised controlled trials

Diabetes Research and Clinical Practice ◽

10.1016/j.diabres.2014.08.003 ◽

2014 ◽

Vol 106 (2) ◽

pp. 264-274 ◽

Cited By ~ 27

Author(s):

David R. Owens ◽

Louise Traylor ◽

Marie-Paule Dain ◽

Wolfgang Landgraf

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Basal Insulin ◽

Randomised Controlled Trials ◽

Pooled Analysis ◽

Treat To Target ◽

Controlled Trials ◽

Efficacy And Safety ◽

Randomised Controlled

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Take Control: A randomized trial evaluating the efficacy and safety of self‐ versus physician‐managed titration of insulin glargine 300 U/mL in patients with uncontrolled type 2 diabetes

Diabetes Obesity and Metabolism ◽

10.1111/dom.13697 ◽

2019 ◽

Vol 21 (7) ◽

pp. 1615-1624 ◽

Cited By ~ 3

Author(s):

David Russell‐Jones ◽

Arnaud Dauchy ◽

Elías Delgado ◽

George Dimitriadis ◽

Hans A. Frandsen ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Randomized Trial ◽

Efficacy And Safety

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Review for "Insulin glargine/lixisenatide fixed‐ratio combination ( iGlarLixi ) compared to premix or addition of meal‐time insulin to basal insulin in people with type 2 diabetes: A systematic review and Bayesian network meta‐analysis"

10.1111/dom.14148/v3/review2 ◽

2020 ◽

Author(s):

CHARLES KHOURI

Keyword(s):

Systematic Review ◽

Type 2 Diabetes ◽

Insulin Glargine ◽

Bayesian Network ◽

Basal Insulin ◽

Meta Analysis ◽

Fixed Ratio ◽

Meal Time

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Indirect comparison of efficacy and safety of insulin glargine/lixisenatide and insulin degludec/insulin aspart in type 2 diabetes patients not controlled on basal insulin

Primary Care Diabetes ◽

10.1016/j.pcd.2020.08.004 ◽

2021 ◽

Vol 15 (1) ◽

pp. 132-137

Author(s):

Anwar Ali Jammah

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Insulin Aspart ◽

Basal Insulin ◽

Indirect Comparison ◽

Insulin Degludec ◽

Efficacy And Safety ◽

Diabetes Patients

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Efficacy and safety of semaglutide in type 2 diabetes compared with sitagliptin, exenatide ER, insulin glargine, basal insulin and placebo: a systematic review

Pharmaceutical Sciences Asia ◽

10.29090/psa.2018.03.123 ◽

2018 ◽

Vol 45 (3) ◽

pp. 123-130

Author(s):

Wei Lin ◽

Naeti Suksomboon

Keyword(s):

Systematic Review ◽

Type 2 Diabetes ◽

Insulin Glargine ◽

Basal Insulin ◽

Efficacy And Safety

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Cost-Effectiveness of Insulin Glargine/Lixisenatide Titratable Fixed-Ratio Combination for Patients with Basal Insulin-Treated Type 2 Diabetes in South Korea

Value in Health ◽

10.1016/j.jval.2018.07.292 ◽

2018 ◽

Vol 21 ◽

pp. S38

Author(s):

H Park ◽

S An ◽

S Park ◽

D Kim ◽

S Jeon ◽

...

Keyword(s):

Type 2 Diabetes ◽

Cost Effectiveness ◽

South Korea ◽

Insulin Glargine ◽

Basal Insulin ◽

Fixed Ratio

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Efficacy and Safety of 1:1 Fixed-Ratio Combination of Insulin Glargine and Lixisenatide Versus Lixisenatide in Japanese Patients With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs: The LixiLan JP-O1 Randomized Clinical Trial

Diabetes Care ◽

10.2337/dc19-2452 ◽

2020 ◽

Vol 43 (6) ◽

pp. 1249-1257

Author(s):

Hirotaka Watada ◽

Akane Takami ◽

Robert Spranger ◽

Atsushi Amano ◽

Yasuhiro Hashimoto ◽

...

Keyword(s):

Type 2 Diabetes ◽

Clinical Trial ◽

Insulin Glargine ◽

Randomized Clinical Trial ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Oral Antidiabetic

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Effect of a single dose of insulin glargine/lixisenatide fixed ratio combination (iGlarLixi) on postprandial glucodynamic response in Japanese patients with type 2 diabetes mellitus: A phase I randomized trial

Diabetes Obesity and Metabolism ◽

10.1111/dom.13757 ◽

2019 ◽

Vol 21 (8) ◽

pp. 2001-2005 ◽

Cited By ~ 4

Author(s):

Megumi Inoue ◽

Martin Lorenz ◽

Hideya Muto ◽

Roland Wesch ◽

Yasuhiro Hashimoto

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Single Dose ◽

Insulin Glargine ◽

Phase I ◽

Randomized Trial ◽

Fixed Ratio ◽

Japanese Patients

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