Efficacy and Safety of 1:1 Fixed-Ratio Combination of Insulin Glargine and Lixisenatide Versus Lixisenatide in Japanese Patients With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs: The LixiLan JP-O1 Randomized Clinical Trial

Hirotaka Watada; Akane Takami; Robert Spranger; Atsushi Amano; Yasuhiro Hashimoto; Elisabeth Niemoeller

doi:10.2337/dc19-2452

Efficacy and Safety of 1:1 Fixed-Ratio Combination of Insulin Glargine and Lixisenatide Versus Lixisenatide in Japanese Patients With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs: The LixiLan JP-O1 Randomized Clinical Trial

Diabetes Care ◽

10.2337/dc19-2452 ◽

2020 ◽

Vol 43 (6) ◽

pp. 1249-1257

Author(s):

Hirotaka Watada ◽

Akane Takami ◽

Robert Spranger ◽

Atsushi Amano ◽

Yasuhiro Hashimoto ◽

...

Keyword(s):

Type 2 Diabetes ◽

Clinical Trial ◽

Insulin Glargine ◽

Randomized Clinical Trial ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Oral Antidiabetic

Download Full-text

Efficacy and safety of insulin glargine/lixisenatide fixed‐ratio combination (iGlarLixi) in Japanese patients with type 2 diabetes mellitus inadequately controlled on basal insulin and oral antidiabetic drugs: The LixiLan JP‐L randomized clinical trial

Diabetes Obesity and Metabolism ◽

10.1111/dom.14005 ◽

2020 ◽

Vol 22 (S4) ◽

pp. 3-13 ◽

Cited By ~ 3

Author(s):

Hideaki Kaneto ◽

Akane Takami ◽

Robert Spranger ◽

Atsushi Amano ◽

Daisuke Watanabe ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Clinical Trial ◽

Type 2 Diabetes Mellitus ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Oral Antidiabetic

Download Full-text

Decision letter for "Efficacy and safety of insulin glargine/lixisenatide fixed‐ratio combination (iGlarLixi) in Japanese patients with type 2 diabetes mellitus inadequately controlled on basal insulin and oral antidiabetic drugs: The LixiLan JP‐L Randomized Clinical Trial"

10.1111/dom.14005/v1/decision1 ◽

2020 ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Clinical Trial ◽

Type 2 Diabetes Mellitus ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Oral Antidiabetic

Download Full-text

Author response for "Efficacy and safety of insulin glargine/lixisenatide fixed‐ratio combination (iGlarLixi) in Japanese patients with type 2 diabetes mellitus inadequately controlled on basal insulin and oral antidiabetic drugs: The LixiLan JP‐L Randomized Clinical Trial"

10.1111/dom.14005/v2/response1 ◽

2020 ◽

Author(s):

Hideaki Kaneto ◽

Akane Takami ◽

Robert Spranger ◽

Atsushi Amano ◽

Daisuke Watanabe ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Clinical Trial ◽

Type 2 Diabetes Mellitus ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Oral Antidiabetic

Download Full-text

Decision letter for "Efficacy and safety of insulin glargine/lixisenatide fixed‐ratio combination (iGlarLixi) in Japanese patients with type 2 diabetes mellitus inadequately controlled on basal insulin and oral antidiabetic drugs: The LixiLan JP‐L Randomized Clinical Trial"

10.1111/dom.14005/v2/decision1 ◽

2020 ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Clinical Trial ◽

Type 2 Diabetes Mellitus ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Oral Antidiabetic

Download Full-text

Review for "Efficacy and safety of insulin glargine/lixisenatide fixed‐ratio combination (iGlarLixi) in Japanese patients with type 2 diabetes mellitus inadequately controlled on basal insulin and oral antidiabetic drugs: The LixiLan JP‐L Randomized Clinical Trial"

10.1111/dom.14005/v1/review2 ◽

2020 ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Clinical Trial ◽

Type 2 Diabetes Mellitus ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Oral Antidiabetic

Download Full-text

Efficacy and safety of insulin glargine/lixisenatide fixed‐ratio combination ( iGlarLixi 1:1) in Japanese patients with type 2 diabetes mellitus inadequately controlled on oral antidiabetic drugs: A randomized, 26‐week, open‐label, multicentre study: The LixiLan JP‐O2 randomized clinical trial

Diabetes Obesity and Metabolism ◽

10.1111/dom.14036 ◽

2020 ◽

Vol 22 (S4) ◽

pp. 14-23 ◽

Cited By ~ 1

Author(s):

Yasuo Terauchi ◽

Takahiro Nakama ◽

Robert Spranger ◽

Atsushi Amano ◽

Takahiro Inoue ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Clinical Trial ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Open Label ◽

Oral Antidiabetic

Download Full-text

Review for "Efficacy and safety of insulin glargine/lixisenatide fixed‐ratio combination (iGlarLixi) in Japanese patients with type 2 diabetes mellitus inadequately controlled on basal insulin and oral antidiabetic drugs: The LixiLan JP‐L Randomized Clinical Trial"

10.1111/dom.14005/v2/review1 ◽

2020 ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Clinical Trial ◽

Type 2 Diabetes Mellitus ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Oral Antidiabetic

Download Full-text

Review for "Efficacy and safety of insulin glargine/lixisenatide fixed‐ratio combination (iGlarLixi) in Japanese patients with type 2 diabetes mellitus inadequately controlled on basal insulin and oral antidiabetic drugs: The LixiLan JP‐L Randomized Clinical Trial"

10.1111/dom.14005/v1/review1 ◽

2019 ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Clinical Trial ◽

Type 2 Diabetes Mellitus ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Oral Antidiabetic

Download Full-text

Decision letter for "Efficacy and safety of insulin glargine/lixisenatide fixed-ratio combination (iGlarLixi 1:1) in Japanese patients with type 2 diabetes mellitus inadequately controlled on oral antidiabetic drugs: A randomized, 26-week, open-label, multicenter study: The L"

10.1111/dom.14036/v3/decision1 ◽

2020 ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Open Label ◽

Oral Antidiabetic

Download Full-text

Decision letter for "Efficacy and safety of insulin glargine/lixisenatide fixed-ratio combination (iGlarLixi 1:1) in Japanese patients with type 2 diabetes mellitus inadequately controlled on oral antidiabetic drugs: A randomized, 26-week, open-label, multicenter study: The L"

10.1111/dom.14036/v2/decision1 ◽

2020 ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Fixed Ratio ◽

Japanese Patients ◽

Efficacy And Safety ◽

Oral Antidiabetic Drugs ◽

Open Label ◽

Oral Antidiabetic

Download Full-text