scholarly journals Trends in Incidence of Diabetes in Pregnancy and Serious Perinatal Outcomes: A Large, Population-Based Study in Ontario, Canada, 1996–2010

Diabetes Care ◽  
2014 ◽  
Vol 37 (6) ◽  
pp. 1590-1596 ◽  
Author(s):  
Denice S. Feig ◽  
Jeremiah Hwee ◽  
Baiju R. Shah ◽  
Giliian L. Booth ◽  
Arlene S. Bierman ◽  
...  
2020 ◽  
Author(s):  
Daniel J Corsi ◽  
Helen Hsu ◽  
Darine El-Chaar ◽  
Deshayne Fell ◽  
Mark Walker

Abstract Cannabis use in pregnancy has increased, and many women continue to use it throughout pregnancy. With the legalization of recreational cannabis in many jurisdictions, there is concern about potentially adverse childhood outcomes related to prenatal exposure.4 Using the provincial birth registry containing information on cannabis use during pregnancy, we will assemble a large, population-based cohort of children born to mothers in Ontario, with and without prenatal exposure to cannabis from birth to 10 years of age. A series of investigations will examine the health effects of prenatal cannabis exposure on child outcomes using novel methods to address confounding. We will link pregnancy and birth data to provincial health administrative databases to ascertain child neurodevelopmental outcomes. The unique aspect of our proposed research is that we plan to utilize an existing population-based perinatal registry combined with administrative datasets for long-term follow up of children using a rich set of covariates and potential confounders to assess the association with cannabis exposure on pregnancy and perinatal outcomes and into childhood.


2020 ◽  
Vol 8 (1) ◽  
pp. e001254
Author(s):  
Lucia Gortazar ◽  
Albert Goday ◽  
Juana Antonia Flores-Le Roux ◽  
Eugènia Sarsanedas ◽  
Antonio Payà ◽  
...  

IntroductionThis study aims to assess trends in the prevalence of pre-existing diabetes and whether the risk of adverse perinatal outcomes decreased in women between 2006 and 2015 in Catalonia, Spain.Research design and methodsA population-based study of 743 762 singleton deliveries between 2006 and 2015 in Catalonia, Spain, was conducted using data from the Spanish Minimum Basic Data Set. Cases of type 1 diabetes (T1DM) and ‘type 2 diabetes and other pre-existing diabetes’ (‘T2DM and other PGD’) were identified using International Classification of Diseases, Ninth Revision, Clinical Modification codes. Crude and age-adjusted annual prevalences were calculated. Poisson regression model was used to assess trends in prevalence and perinatal outcomes during the study period.ResultsOverall prevalences of pre-existing diabetes, T1DM and ‘T2DM and other PGD’ were 0.52% (95% CI 0.51 to 0.54), 0.17% (95% CI 0.17 to 0.18) and 0.35% (95% CI 0.33 to 0.36), respectively. From 2006 to 2015, rates increased for pre-existing diabetes (from 0.43 (95% CI 0.39 to 0.48) to 0.56% (0.50 to 0.62), p<0.001), T1DM (from 0.14 (0.11 to 0.17) to 0.20% (0.17 to 0.23), p<0.001) and ‘T2DM and other PGD’ (from 0.29 (0.25 to 0.33) to 0.36% (0.31 to 0.40), p<0.001). Pre-eclampsia rose in women with pre-existing diabetes (from 4.38% to 8.97%, adjusted p<0.001), T1DM (from 3.85% to 12.88%, p=0.005) and ‘T2DM and other PGD’ (from 4.63% to 6.78%, adjusted p=0.01). Prevalence of prematurity, cesarean section and small for gestational age remained stable in all diabetes groups. However, the prevalence of macrosomia fell in women with pre-existing diabetes (from 18.18% to 11.9%, adjusted p=0.011) and ‘T2DM and other PGD’ (from 14.71% to 11.06%, non-adjusted p=0.022, adjusted p=0.305) and large for gestational age decreased in all diabetes groups (from 39.73% to 30.25% in pre-existing diabetes, adjusted p=0.004).ConclusionsThe prevalence of pre-existing diabetes increased significantly in Catalonia between 2006 and 2015. Despite improvements in outcomes related to excessive birth weight, pre-eclampsia rates are rising and overall perinatal outcomes in women with pre-existing diabetes continue to be markedly worse than in the population without diabetes.


2005 ◽  
Vol 192 (6) ◽  
pp. 1856-1862 ◽  
Author(s):  
Ahmad O. Hammoud ◽  
Emmanuel Bujold ◽  
Yoram Sorokin ◽  
Christiane Schild ◽  
Martin Krapp ◽  
...  

2020 ◽  
Vol 8 (7) ◽  
pp. 482-482 ◽  
Author(s):  
Jin-Feng Huang ◽  
Jianfei Shen ◽  
Xiao Li ◽  
Ramesh Rengan ◽  
Nicola Silvestris ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document