scholarly journals Obstetric and Perinatal Outcomes in Type 1 Diabetic Pregnancies: A large, population-based study

Diabetes Care ◽  
2009 ◽  
Vol 32 (11) ◽  
pp. 2005-2009 ◽  
Author(s):  
M. Persson ◽  
M. Norman ◽  
U. Hanson
Diabetes Care ◽  
2014 ◽  
Vol 38 (2) ◽  
pp. 323-328 ◽  
Author(s):  
Richard A. Oram ◽  
Timothy J. McDonald ◽  
Beverley M. Shields ◽  
Michelle M. Hudson ◽  
Maggie H. Shepherd ◽  
...  

Diabetes Care ◽  
2014 ◽  
Vol 37 (6) ◽  
pp. 1590-1596 ◽  
Author(s):  
Denice S. Feig ◽  
Jeremiah Hwee ◽  
Baiju R. Shah ◽  
Giliian L. Booth ◽  
Arlene S. Bierman ◽  
...  

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Børge Sivertsen ◽  
Keith J Petrie ◽  
Ane Wilhelmsen-Langeland ◽  
Mari Hysing

2020 ◽  
Vol 8 (1) ◽  
pp. e001254
Author(s):  
Lucia Gortazar ◽  
Albert Goday ◽  
Juana Antonia Flores-Le Roux ◽  
Eugènia Sarsanedas ◽  
Antonio Payà ◽  
...  

IntroductionThis study aims to assess trends in the prevalence of pre-existing diabetes and whether the risk of adverse perinatal outcomes decreased in women between 2006 and 2015 in Catalonia, Spain.Research design and methodsA population-based study of 743 762 singleton deliveries between 2006 and 2015 in Catalonia, Spain, was conducted using data from the Spanish Minimum Basic Data Set. Cases of type 1 diabetes (T1DM) and ‘type 2 diabetes and other pre-existing diabetes’ (‘T2DM and other PGD’) were identified using International Classification of Diseases, Ninth Revision, Clinical Modification codes. Crude and age-adjusted annual prevalences were calculated. Poisson regression model was used to assess trends in prevalence and perinatal outcomes during the study period.ResultsOverall prevalences of pre-existing diabetes, T1DM and ‘T2DM and other PGD’ were 0.52% (95% CI 0.51 to 0.54), 0.17% (95% CI 0.17 to 0.18) and 0.35% (95% CI 0.33 to 0.36), respectively. From 2006 to 2015, rates increased for pre-existing diabetes (from 0.43 (95% CI 0.39 to 0.48) to 0.56% (0.50 to 0.62), p<0.001), T1DM (from 0.14 (0.11 to 0.17) to 0.20% (0.17 to 0.23), p<0.001) and ‘T2DM and other PGD’ (from 0.29 (0.25 to 0.33) to 0.36% (0.31 to 0.40), p<0.001). Pre-eclampsia rose in women with pre-existing diabetes (from 4.38% to 8.97%, adjusted p<0.001), T1DM (from 3.85% to 12.88%, p=0.005) and ‘T2DM and other PGD’ (from 4.63% to 6.78%, adjusted p=0.01). Prevalence of prematurity, cesarean section and small for gestational age remained stable in all diabetes groups. However, the prevalence of macrosomia fell in women with pre-existing diabetes (from 18.18% to 11.9%, adjusted p=0.011) and ‘T2DM and other PGD’ (from 14.71% to 11.06%, non-adjusted p=0.022, adjusted p=0.305) and large for gestational age decreased in all diabetes groups (from 39.73% to 30.25% in pre-existing diabetes, adjusted p=0.004).ConclusionsThe prevalence of pre-existing diabetes increased significantly in Catalonia between 2006 and 2015. Despite improvements in outcomes related to excessive birth weight, pre-eclampsia rates are rising and overall perinatal outcomes in women with pre-existing diabetes continue to be markedly worse than in the population without diabetes.


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