scholarly journals Fasting Insulin Level Is Positively Associated With Incidence of Hypertension Among American Young Adults: A 20-year follow-up study

Diabetes Care ◽  
2012 ◽  
Vol 35 (7) ◽  
pp. 1532-1537 ◽  
Author(s):  
P. Xun ◽  
K. Liu ◽  
W. Cao ◽  
S. Sidney ◽  
O. D. Williams ◽  
...  
Keyword(s):  
Young Adults ◽  
Insulin Level ◽  
Fasting Insulin ◽  
Follow Up Study ◽  
Fasting Insulin Level ◽  
American Young Adults

scholarly journals Effect of dietary fat intake and genetic risk on glucose and insulin-related traits in Brazilian young adults

2021 ◽  
Author(s):  
Sooad Alsulami ◽  
Nathália Teixeira Cruvinel ◽  
Nara Rubia da Silva ◽  
Ana Carolina Antoneli ◽  
Julie A. Lovegrove ◽  
...  
Keyword(s):  
Metabolic Disease ◽  
Young Adults ◽  
Genetic Risk ◽  
Insulin Level ◽  
Dietary Factors ◽  
Fat Intake ◽  
Fasting Insulin ◽  
Risk Alleles ◽  
Glucose Ratio ◽  
Fasting Insulin Level

Abstract Purpose The development of metabolic diseases such as type 2 diabetes (T2D) is closely linked to a complex interplay between genetic and dietary factors. The prevalence of abdominal obesity, hyperinsulinemia, dyslipidaemia, and high blood pressure among Brazilian adolescents is increasing and hence, early lifestyle interventions targeting these factors might be an effective strategy to prevent or slow the progression of T2D. Methods We aimed to assess the interaction between dietary and genetic factors on metabolic disease-related traits in 200 healthy Brazilian young adults. Dietary intake was assessed using 3-day food records. Ten metabolic disease-related single nucleotide polymorphisms (SNPs) were used to construct a metabolic-genetic risk score (metabolic-GRS). Results We found significant interactions between the metabolic-GRS and total fat intake on fasting insulin level (Pinteraction = 0.017), insulin-glucose ratio (Pinteraction = 0.010) and HOMA-B (Pinteraction = 0.002), respectively, in addition to a borderline GRS-fat intake interaction on HOMA-IR (Pinteraction = 0.051). Within the high-fat intake category [37.98 ± 3.39% of total energy intake (TEI)], individuals with ≥ 5 risk alleles had increased fasting insulin level (P = 0.021), insulin-glucose ratio (P = 0.010), HOMA-B (P = 0.001) and HOMA-IR (P = 0.053) than those with < 5 risk alleles. Conclusion Our study has demonstrated a novel GRS-fat intake interaction in young Brazilian adults, where individuals with higher genetic risk and fat intake had increased glucose and insulin-related traits than those with lower genetic risk. Large intervention and follow-up studies with an objective assessment of dietary factors are needed to confirm our findings.

scholarly journals Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to Diabetes Incidence Among American Young Adults: A 30-Year Follow-up Study

Diabetes Care ◽  
2020 ◽  
Vol 43 (10) ◽  
pp. 2426-2434
Author(s):  
Jie Zhu ◽  
Cheng Chen ◽  
Liping Lu ◽  
Kefeng Yang ◽  
Jared Reis ◽  
...  
Keyword(s):  
Young Adults ◽  
Vitamin B12 ◽  
Vitamin B6 ◽  
Diabetes Incidence ◽  
Follow Up Study ◽  
American Young Adults

scholarly journals Folate intake and incidence of hypertension among American young adults: a 20-y follow-up study

2012 ◽  
Vol 95 (5) ◽  
pp. 1023-1030 ◽  
Author(s):  
Pengcheng Xun ◽  
Kiang Liu ◽  
Catherine M Loria ◽  
Deborah Bujnowski ◽  
James M Shikany ◽  
...  
Keyword(s):  
Young Adults ◽  
Folate Intake ◽  
Follow Up Study ◽  
American Young Adults

scholarly journals Magnesium intake is inversely associated with risk of obesity in a 30-year prospective follow-up study among American young adults

2020 ◽  
Vol 59 (8) ◽  
pp. 3745-3753 ◽  
Author(s):  
Liping Lu ◽  
Cheng Chen ◽  
Kefeng Yang ◽  
Jie Zhu ◽  
Pengcheng Xun ◽  
...  
Keyword(s):  
Young Adults ◽  
Magnesium Intake ◽  
Follow Up Study ◽  
American Young Adults

scholarly journals Elevated Fasting Insulin Level Significantly Increases the Risk of Microalbuminuria

2014 ◽  
Vol 79 (1) ◽  
pp. 210-215 ◽  
Author(s):  
Jae-Hong Ryoo ◽  
Sung Keun Park ◽  
Ju Young Jung
Keyword(s):  
Insulin Level ◽  
Fasting Insulin ◽  
Fasting Insulin Level

Psychotropic medication use among personality disordered young adults. A follow-up study among former adolescent psychiatric inpatients

2020 ◽  
Vol 293 ◽  
pp. 113449
Author(s):  
Liisa Kantojärvi ◽  
Helinä Hakko ◽  
Milla Mukka ◽  
Anniina Käyhkö ◽  
Pirkko Riipinen ◽  
...  
Keyword(s):  
Young Adults ◽  
Psychotropic Medication ◽  
Medication Use ◽  
Psychiatric Inpatients ◽  
Follow Up Study ◽  
Personality Disordered
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