scholarly journals Changes in Physical Fitness Predict Improvements in Modifiable Cardiovascular Risk Factors Independently of Body Weight Loss in Subjects With Type 2 Diabetes Participating in the Italian Diabetes and Exercise Study (IDES)

Diabetes Care ◽  
2012 ◽  
Vol 35 (6) ◽  
pp. 1347-1354 ◽  
Author(s):  
S. Balducci ◽  
S. Zanuso ◽  
P. Cardelli ◽  
L. Salvi ◽  
G. Mazzitelli ◽  
...  
Diabetes Care ◽  
2011 ◽  
Vol 34 (7) ◽  
pp. 1481-1486 ◽  
Author(s):  
R. R. Wing ◽  
W. Lang ◽  
T. A. Wadden ◽  
M. Safford ◽  
W. C. Knowler ◽  
...  

2012 ◽  
Vol 21 (5) ◽  
pp. 608-617 ◽  
Author(s):  
Bethany Barone Gibbs ◽  
Frederick L Brancati ◽  
Haiying Chen ◽  
Mace Coday ◽  
John M Jakicic ◽  
...  

2021 ◽  
Author(s):  
Stefano Balducci ◽  
Jonida Haxhi ◽  
Massimo Sacchetti ◽  
Giorgio Orlando ◽  
Patrizia Cardelli ◽  
...  

<a><strong>Objective.</strong></a> In the Italian Diabetes and Exercise Study_2, a behavioral counseling <a>promoted</a> a sustained increase in physical activity (PA) volume (+3.3 metabolic equivalents-hour·week<sup>-1</sup>), moderate-to-vigorous-intensity PA (MVPA, +6.4 min·day<sup>-1</sup>), and light-intensity PA (LPA, +0.8 hours·day<sup>-1</sup>) and decrease in sedentary time (SED-time, -0.8 hours·day<sup>-1</sup>). Here, we investigated <a>the relationships of changes in PA/SED-time with changes in physical fitness and cardio-metabolic risk profile in individuals with type 2 diabetes</a>. <p><b>Research Design and Methods. </b><a>In this 3-year randomized clinical trial, 300 physically inactive and sedentary patients were randomized 1:1 to receive one-month theoretical and practical counseling once-a-year or standard care. </a>Changes in physical fitness and cardiovascular risk factors/scores according to quartiles of accelerometer-measured changes in PA/SED-time were assessed, together with univariate and multivariable associations between these parameters<a>, in the whole cohort and by study arm</a>.</p> <p><b>Results. </b>Physical fitness increased and HbA<sub>1c</sub> and coronary heart disease 10-year risk scores decreased with quartiles of MVPA and SED-time change. In quartile IV of MVPA increase and SED-time decrease, cardiorespiratory fitness increased by 5.23 and 4.49 ml·min<sup>-1</sup>·kg<sup>-1</sup> and HbA<sub>1c</sub> decreased by 0.73 and 0.85%, respectively. Univariate correlations confirmed these relationships and mean changes in both MPVA and SED-time predicted changes in physical fitness and cardiovascular risk factors/scores independently of one another and of other confounders. Similar findings were observed with LPA and PA volume and in each group separately.</p> <p><b>Conclusions. </b>Even modest increments in MVPA may have a clinically meaningful impact and reallocating SED-time to LPA may also contribute to improve outcomes, possibly by increasing total energy expenditure.</p>


2008 ◽  
Vol 9 (1) ◽  
pp. 98
Author(s):  
E.A. Stolina ◽  
M.V. Arkhipov ◽  
B.L. Meylakh ◽  
S.V. Nudelman ◽  
A.I. Prudkov ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document