scholarly journals Arterial Stiffness Is Increased in Patients With Type 1 Diabetes Without Cardiovascular Disease: A potential role of low-grade inflammation

Diabetes Care ◽  
2012 ◽  
Vol 35 (5) ◽  
pp. 1083-1089 ◽  
Author(s):  
G. Llaurado ◽  
V. Ceperuelo-Mallafre ◽  
C. Vilardell ◽  
R. Simo ◽  
N. Freixenet ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Type 1 Diabetes ◽  
Arterial Stiffness ◽  
Potential Role ◽  
Low Grade ◽  
Low Grade Inflammation

scholarly journals FGF-23/Vitamin D Axis in Type 1 Diabetes: The Potential Role of Mineral Metabolism in Arterial Stiffness

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0140222 ◽  
Author(s):  
Gemma Llauradó ◽  
Ana Megia ◽  
Albert Cano ◽  
Olga Giménez-Palop ◽  
Inmaculada Simón ◽  
...  
Keyword(s):  
Vitamin D ◽  
Type 1 Diabetes ◽  
Arterial Stiffness ◽  
Potential Role ◽  
Mineral Metabolism ◽  
Fgf 23

scholarly journals Prognostic value of arterial stiffness measurements in cardiovascular disease, diabetes, and its complications: The potential role of sodium‐glucose co‐transporter‐2 inhibitors

2020 ◽  
Vol 22 (4) ◽  
pp. 562-571 ◽  
Author(s):  
Dimitrios Patoulias ◽  
Christodoulos Papadopoulos ◽  
Konstantinos Stavropoulos ◽  
Ioanna Zografou ◽  
Michael Doumas ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Arterial Stiffness ◽  
Prognostic Value ◽  
Potential Role

The Potential Role of PTPN-22 C1858T Gene Polymorphism in the Pathogenesis of Type 1 Diabetes in Saudi Population

2018 ◽  
Vol 47 (5) ◽  
pp. 521-533 ◽  
Author(s):  
Khaled A. Alswat ◽  
Amre Nasr ◽  
Mohammed S. Al Dubayee ◽  
Iman M. Talaat ◽  
Adnan A. Alsulaimani ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Gene Polymorphism ◽  
Potential Role ◽  
Saudi Population

scholarly journals The Role of Markers of Low-Grade Inflammation for the Early Time Course of Glycemic Control, Glucose Disappearance Rate, and β-Cell Function in Recently Diagnosed Type 1 and Type 2 Diabetes

Diabetes Care ◽  
2015 ◽  
Vol 38 (9) ◽  
pp. 1758-1767 ◽  
Author(s):  
Katharina S. Weber ◽  
Bettina Nowotny ◽  
Klaus Strassburger ◽  
Giovanni Pacini ◽  
Karsten Müssig ◽  
...  
Keyword(s):  
Time Course ◽  
Cell Function ◽  
Early Time ◽  
Low Grade ◽  
Β Cell ◽  
Β Cell Function ◽  
Low Grade Inflammation

Role of Physical Activity and Sedentary Behavior on Early Markers of Cardiovascular Disease in Adolescents With Type 1 Diabetes: The CARDEA Study

2021 ◽  
Vol 45 (7) ◽  
pp. S30
Author(s):  
Soren Harnois-Leblanc ◽  
Vanessa Mcnealis ◽  
Matthias Friedrich ◽  
Andraea Van Hulst ◽  
Anne Monique Nuyt ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cardiovascular Disease ◽  
Type 1 Diabetes ◽  
Sedentary Behavior ◽  
Early Markers

Low Grade Inflammation in Juvenile Obesity and Type 1 Diabetes Associated with Early Signs of Atherosclerosis

2004 ◽  
Vol 112 (07) ◽  
pp. 378-382 ◽  
Author(s):  
H. Mangge ◽  
K. Schauenstein ◽  
L. Stroedter ◽  
A. Griesl ◽  
W. Maerz ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Low Grade ◽  
Early Signs ◽  
Juvenile Obesity ◽  
Low Grade Inflammation

scholarly journals The Role of Oxidative Stress and Inflammation in Cardiovascular Aging

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Junzhen Wu ◽  
Shijin Xia ◽  
Bill Kalionis ◽  
Wenbin Wan ◽  
Tao Sun
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Disease ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Low Grade ◽  
Oxygen Species ◽  
Age Related ◽  
Vascular Elasticity ◽  
Low Grade Inflammation

Age is an independent risk factor of cardiovascular disease, even in the absence of other traditional factors. Emerging evidence in experimental animal and human models has emphasized a central role for two main mechanisms of age-related cardiovascular disease: oxidative stress and inflammation. Excess reactive oxygen species (ROS) and superoxide generated by oxidative stress and low-grade inflammation accompanying aging recapitulate age-related cardiovascular dysfunction, that is, left ventricular hypertrophy, fibrosis, and diastolic dysfunction in the heart as well as endothelial dysfunction, reduced vascular elasticity, and increased vascular stiffness. We describe the signaling involved in these two main mechanisms that include the factors NF-κB, JunD, p66Shc, and Nrf2. Potential therapeutic strategies to improve the cardiovascular function with aging are discussed, with a focus on calorie restriction, SIRT1, and resveratrol.

scholarly journals Impact of Diabetes on Cardiovascular Disease: An Update

2013 ◽  
Vol 2013 ◽  
pp. 1-15 ◽  
Author(s):  
Alessandra Saldanha de Mattos Matheus ◽  
Lucianne Righeti Monteiro Tannus ◽  
Roberta Arnoldi Cobas ◽  
Catia C. Sousa Palma ◽  
Carlos Antonio Negrato ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Disease ◽  
Subclinical Atherosclerosis ◽  
Low Grade ◽  
Stress Markers ◽  
Asymptomatic Patients ◽  
Genes And Environment ◽  
The Impact ◽  
Low Grade Inflammation

Cardiovascular diseases are the most prevalent cause of morbidity and mortality among patients with type 1 or type 2 diabetes. The proposed mechanisms that can link accelerated atherosclerosis and increased cardiovascular risk in this population are poorly understood. It has been suggested that an association between hyperglycemia and intracellular metabolic changes can result in oxidative stress, low-grade inflammation, and endothelial dysfunction. Recently, epigenetic factors by different types of reactions are known to be responsible for the interaction between genes and environment and for this reason can also account for the association between diabetes and cardiovascular disease. The impact of clinical factors that may coexist with diabetes such as obesity, dyslipidemia, and hypertension are also discussed. Furthermore, evidence that justify screening for subclinical atherosclerosis in asymptomatic patients is controversial and is also matter of this review. The purpose of this paper is to describe the association between poor glycemic control, oxidative stress, markers of insulin resistance, and of low-grade inflammation that have been suggested as putative factors linking diabetes and cardiovascular disease.

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