scholarly journals The Relation of Diabetes, Impaired Fasting Blood Glucose, and Insulin Resistance to Left Ventricular Structure and Function in African Americans: The Jackson Heart Study

Diabetes Care ◽  
2011 ◽  
Vol 34 (2) ◽  
pp. 507-509 ◽  
Author(s):  
E. R. Fox ◽  
D. F. Sarpong ◽  
J. C. Cook ◽  
T. E. Samdarshi ◽  
H. S. Nagarajarao ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Blood Glucose ◽  
African Americans ◽  
Fasting Blood Glucose ◽  
Left Ventricular ◽  
Structure And Function ◽  
Jackson Heart Study ◽  
Ventricular Structure ◽  
Heart Study ◽  
And Function

Abstract 13641: Serum Vitamin D3 Levels, Left Ventricular Structure and Incident Hospitalization for Heart Failure With Preserved Ejection Fraction in African Americans: The Jackson Heart Study

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Daisuke Kamimura ◽  
Amil M Shah ◽  
Adebamike Oshunbade ◽  
Arsalan Hamid ◽  
Robert Mentz ◽  
...  
Keyword(s):  
Heart Failure ◽  
African Americans ◽  
Ejection Fraction ◽  
Serum Vitamin ◽  
Left Ventricular ◽  
Structure And Function ◽  
Preserved Ejection Fraction ◽  
Lower Serum ◽  
Heart Study ◽  
And Function

Background: Lower serum vitamin D3 (VitD3) concentration has been associated with cardiovascular disease. However, the associations between serum VitD3 levels and left ventricular (LV) structure and function and heart failure with preserved ejection fraction (HFpEF) have not been well-characterized community. The prevalence of VitD3 deficiency is higher among African Americans than in other race/ethnicity groups. We hypothesized that serum VitD3 levels are associated with LV concentric remodeling and incident heart failure (HF) in African Americans. Methods and Results: Among 4872 African Americans in the Jackson Heart Study cohort, we investigated the relationships between serum VitD3 levels and LV structure and function, evaluated with echocardiography, and incident HF hospitalization, categorized either HF with reduced EF (HFrEF: EF<50%) or HFpEF (EF≥50%). The median and interquartile serum VitD3 levels were 12.0 (8.6-16.7) ng/mL. After adjustment for age, sex, body mass index, systolic blood pressure, anti-hypertensive medication use, current smoking status, and estimated glomerular filtration rate, lower VitD3 levels were associated with greater septal and posterior wall thickness and plasma brain natriuretic peptide (BNP) levels, but not with LV mass index or LVEF (Table). Over a median follow-up period of 11 (10.3~11) years, 313 participants developed incident HF (7.79 cases per 1,000 person-years), including 128 (41%) HFrEF and 185 (59%) HFpEF cases. After adjustment, lower serum VitD3 levels were associated with higher incidence of HF overall and levels seemed to be mostly related to HFpEF (Table). Conclusion: In this community-based African American cohort, lower serum VitD3 levels were associated with LV concentric remodeling and incident HF, mainly HFpEF. Further investigation is required to examine whether the supplementation of VitD3 can prevent LV concentric remodeling and incident HFpEF in African Americans.

Exposure To Traffic Pollution And Cardiac Structure And Function In African Americans: Results From The Jackson Heart Study

2015 ◽  
Vol 2015 (1) ◽  
pp. 2758
Author(s):  
Anne M Weaver ◽  
Demarc A. Hickson ◽  
Masoor Kamalesh ◽  
Melissa Eliot ◽  
Wen-Chih Wu ◽  
...  
Keyword(s):  
African Americans ◽  
Structure And Function ◽  
Traffic Pollution ◽  
Cardiac Structure ◽  
Jackson Heart Study ◽  
Heart Study ◽  
Cardiac Structure And Function ◽  
And Function

scholarly journals Associations of Insulin Levels With Left Ventricular Structure and Function in American Indians : The Strong Heart Study

Diabetes ◽  
2002 ◽  
Vol 51 (5) ◽  
pp. 1543-1547 ◽  
Author(s):  
A. Ilercil ◽  
R. B. Devereux ◽  
M. J. Roman ◽  
M. Paranicas ◽  
M. J. O'Grady ◽  
...  
Keyword(s):  
American Indians ◽  
Left Ventricular ◽  
Structure And Function ◽  
Strong Heart Study ◽  
Left Ventricular Structure ◽  
Insulin Levels ◽  
Ventricular Structure ◽  
Heart Study ◽  
And Function
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