scholarly journals Left ventricular structure and function predict clinical cardiovascular risk in prehypertension: the strong heart study

2004 ◽  
Vol 17 (5) ◽  
pp. S29
Author(s):  
M LAWRENCEWRIGHT
Keyword(s):  
Cardiovascular Risk ◽  
Left Ventricular ◽  
Structure And Function ◽  
Strong Heart Study ◽  
Left Ventricular Structure ◽  
Ventricular Structure ◽  
Heart Study ◽  
And Function

scholarly journals Associations of Insulin Levels With Left Ventricular Structure and Function in American Indians : The Strong Heart Study

Diabetes ◽  
2002 ◽  
Vol 51 (5) ◽  
pp. 1543-1547 ◽  
Author(s):  
A. Ilercil ◽  
R. B. Devereux ◽  
M. J. Roman ◽  
M. Paranicas ◽  
M. J. O'Grady ◽  
...  
Keyword(s):  
American Indians ◽  
Left Ventricular ◽  
Structure And Function ◽  
Strong Heart Study ◽  
Left Ventricular Structure ◽  
Insulin Levels ◽  
Ventricular Structure ◽  
Heart Study ◽  
And Function

Relationship of impaired glucose tolerance to left ventricular structure and function: The Strong Heart Study

2001 ◽  
Vol 141 (6) ◽  
pp. 992-998 ◽  
Author(s):  
Arzu Ilercil ◽  
Richard B. Devereux ◽  
Mary J. Roman ◽  
Mary Paranicas ◽  
Michael J. O’Grady ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Left Ventricular ◽  
Structure And Function ◽  
Strong Heart Study ◽  
Left Ventricular Structure ◽  
Ventricular Structure ◽  
Heart Study ◽  
And Function ◽  
Relationship Of

Maternal preeclampsia and cardiac left ventricular structure and function in term infants in the copenhagen baby heart study

2019 ◽  
Vol 17 ◽  
pp. S31
Author(s):  
Ottilia Vøgg ◽  
Jonas Ghouse ◽  
Anne-Sophie Sillesen ◽  
Christian Pihl ◽  
Anna Axelsson Raja ◽  
...  
Keyword(s):  
Left Ventricular ◽  
Structure And Function ◽  
Term Infants ◽  
Left Ventricular Structure ◽  
Ventricular Structure ◽  
Heart Study ◽  
And Function

scholarly journals Association between maternal diabetes and cardiac left ventricular structure and function in the neonate: a study from the Copenhagen Baby Heart Study

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
J Ghouse ◽  
O Voegg ◽  
A.S Sillesen ◽  
C Pihl ◽  
A.R Axelsson ◽  
...  
Keyword(s):  
Diastolic Function ◽  
Heart Defects ◽  
Posterior Wall ◽  
Maternal Diabetes ◽  
Left Ventricular ◽  
Structure And Function ◽  
Left Ventricular Structure ◽  
Ventricular Structure ◽  
Heart Study ◽  
And Function

Abstract Background Prenatal exposure to maternal diabetes has been associated with increased risk of congenital heart defects. Purpose To evaluate whether maternal diabetes is associated with more subtle morphological and functional cardiac changes in neonates without congenital heart defects. Methods We included 17,869 newborns sampled from the Copenhagen Baby Heart Study, all of whom underwent transthoracic echocardiography within 30 days of delivery. We investigated the association between exposure to maternal diabetes (pre-existing diabetes [type 1 or type 2 diabetes] or gestational diabetes [GDM]) and the neonates' echocardiographic indices of left ventricular structure (left posterior wall thickness in end-diastole [LVPWd], interventricular septum thickness in end-diastole [IVSd], left ventricular internal diameter in end-systole [LVIDs] and end-diastole [LVIDd]), systolic function (fractional shortening [FS], stroke volume [SV]) and diastolic function (mitral valve peak early and atrial filling velocities, deceleration time of early filling, and E/A-ratio), using linear and logistic regression. Models were adjusted for maternal age, infant sex, infant birth weight for gestational age and gestational age in days. In additional analyses, we evaluated the relationship between HbA1C levels in first and third trimester and left ventricular structure and function. Results We found that infants exposed to pre-existing maternal diabetes (n=x) had, on average, a thicker LVPWd (mean difference 0.12 mm [95% CI: 0.06–0.19]), a smaller LVIDs (−0.27 mm [95% CI: −0.46, −0.07]) and LVIDd (−0.43 mm [95% CI: −0.66, −0.19]), and decreased SV (−0.50 ml [95% CI: −0.77, −0.23]). We found no significant differences in IVSd, FS, and measures of diastolic function for infants exposed to pre-existing maternal diabetes compared with infants not exposed to diabetes. Infants exposed to GDM (n=) also had thicker LVPWd (0.06 mm [95% CI: −0.28, −0.01]) and smaller LVIDs (−0.15 mm [95% CI: −0.28, −0.01]); however, on average, IVSd, LVIDd, and measures of systolic and diastolic function did not differ for infants born to mothers with and without GDM. We observed no consistent association between HbA1C levels measured early and late in pregnancy in mothers with diabetes and indices of left ventricular structure and function. Conclusion In conclusion, we found that exposure to maternal pre-existing diabetes, and to a lesser degree GDM, was associated with changes in neonatal left ventricular structure and function, including a thicker left ventricular posterior wall, smaller left ventricular internal diameters, and lower stroke volumes. Funding Acknowledgement Type of funding source: Foundation. Main funding source(s): Rigsbospitalet Research Foundation

Sign in / Sign up

Export Citation Format

Share Document