scholarly journals Plasma Growth Differentiation Factor-15 Independently Predicts All-Cause and Cardiovascular Mortality As Well As Deterioration of Kidney Function in Type 1 Diabetic Patients With Nephropathy

Diabetes Care ◽  
2010 ◽  
Vol 33 (7) ◽  
pp. 1567-1572 ◽  
Author(s):  
M. Lajer ◽  
A. Jorsal ◽  
L. Tarnow ◽  
H.-H. Parving ◽  
P. Rossing
Keyword(s):  
Kidney Function ◽  
Cardiovascular Mortality ◽  
Diabetic Patients ◽  
Growth Differentiation Factor 15 ◽  
Differentiation Factor ◽  
Type 1 Diabetic Patients

scholarly journals Plasma osteoprotegerin levels are associated with glycaemic status, systolic blood pressure, kidney function and cardiovascular morbidity in type 1 diabetic patients

2006 ◽  
Vol 154 (1) ◽  
pp. 75-81 ◽  
Author(s):  
Lars Melholt Rasmussen ◽  
Lise Tarnow ◽  
Troels Krarup Hansen ◽  
Hans-Henrik Parving ◽  
Allan Flyvbjerg
Keyword(s):  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Systolic Blood Pressure ◽  
Kidney Function ◽  
Vascular Complications ◽  
Diabetic Patients ◽  
Diabetic Vascular Complications ◽  
Patients With Diabetes ◽  
Type 1 Diabetic Patients

Objective: The bone-related peptide osteoprotegerin (OPG) has recently been found in increased amounts in the vasculature in diabetes. It is produced by vascular smooth muscle and endothelial cells, and may be implicated in the development of vascular calcifications. OPG is present in the circulation, where increased amounts have been observed in patients with diabetes. In this study, we examined whether plasma OPG is associated with the glycaemic and vascular status of patients with type 1 diabetes. Methods: Two gender-, age- and duration-comparable groups of type 1 diabetic patients either with (n = 199) or without (n = 192) signs of diabetic nephropathy were studied. Plasma OPG was determined by an ELISA. Results: The plasma OPG concentration was significantly higher in patients with nephropathy than those without (3.11 (2.49–3.99) vs 2.57 (2.19–3.21) (median (interquartiles), ng/ml), P < 0.001). Plasma OPG correlated with haemoglobin A1c (HbA1c), systolic blood pressure and age in both groups and, in addition, with kidney function in the nephropathic group. These correlations remained significant in multivariate models. In addition, we found that plasma OPG concentrations were increased among patients with cardiovascular diseases (CVD), both in the normoalbuminuric and the nephropathic groups. The differences between nephropathic and normoalbuminuric, as well as subgroups with and without CVD, could largely be ascribed to changes in HbA1c, age, systolic blood pressure and creatinine. Conclusion: OPG is associated with glycaemic control and CVD in patients with type 1 diabetes, compatible with the hypothesis that OPG is associated with the development of diabetic vascular complications.

scholarly journals Plasma osteoprotegerin levels predict cardiovascular and all-cause mortality and deterioration of kidney function in type 1 diabetic patients with nephropathy

Diabetologia ◽  
2008 ◽  
Vol 51 (11) ◽  
pp. 2100-2107 ◽  
Author(s):  
A. Jorsal ◽  
L. Tarnow ◽  
A. Flyvbjerg ◽  
H.-H. Parving ◽  
P. Rossing ◽  
...  
Keyword(s):  
Kidney Function ◽  
Diabetic Patients ◽  
All Cause Mortality ◽  
Type 1 Diabetic Patients

Sex-related association of serum uric acid with inflammation, kidney function and blood pressure in type 1 diabetic patients

2018 ◽  
Vol 19 (5) ◽  
pp. 1014-1019 ◽  
Author(s):  
Bartosz Słomiński ◽  
Maria Skrzypkowska ◽  
Monika Ryba-Stanisławowska ◽  
Agnieszka Brandt
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Kidney Function ◽  
Diabetic Patients ◽  
Type 1 Diabetic Patients ◽  
Related Association

scholarly journals Lack of impact of low-dose acetylsalicylic acid on kidney function in type 1 diabetic patients with microalbuminuria

Diabetes Care ◽  
2000 ◽  
Vol 23 (12) ◽  
pp. 1742-1745 ◽  
Author(s):  
H. P. Hansen ◽  
P. H. Gaede ◽  
B. R. Jensen ◽  
H. H. Parving
Keyword(s):  
Acetylsalicylic Acid ◽  
Kidney Function ◽  
Low Dose ◽  
Diabetic Patients ◽  
Type 1 Diabetic Patients

Acute Effects of a Somatostatin Analogue on Kidney Function in Type 1 Diabetic Patients

1990 ◽  
Vol 7 (4) ◽  
pp. 304-309 ◽  
Author(s):  
M. Mau Pedersen ◽  
S. Engkjaer Christensen ◽  
J. Sandahl Christiansen ◽  
E. Bjerregaard Pedersen ◽  
C.E. Mogensen ◽  
...  
Keyword(s):  
Kidney Function ◽  
Diabetic Patients ◽  
Somatostatin Analogue ◽  
Acute Effects ◽  
Type 1 Diabetic Patients

Is there a relationship between body composition and insulin regimen modality in type 1 diabetic patients?

2014 ◽  
Author(s):  
Merve Yilmaz ◽  
Arzu Gedik ◽  
Simge Yilmaz ◽  
Belgin Bektas ◽  
Dilek Cimrin ◽  
...  
Keyword(s):  
Body Composition ◽  
Diabetic Patients ◽  
Insulin Regimen ◽  
Type 1 Diabetic Patients

Insulin-mimetic effects of short-term Rapamycin in type 1 diabetic patients prior islet transplantation

2017 ◽  
Author(s):  
Federica Ermetici ◽  
Silvia Briganti ◽  
Stefano Benedini ◽  
Roberto Codella ◽  
Paola Maffi ◽  
...  
Keyword(s):  
Islet Transplantation ◽  
Diabetic Patients ◽  
Short Term ◽  
Insulin Mimetic ◽  
Type 1 Diabetic Patients
Sign in / Sign up

Export Citation Format

Share Document