scholarly journals The Effect of Resistance Training on Functional Capacity and Quality of Life in Individuals with High and Low Numbers of Metabolic Risk Factors

Diabetes Care ◽  
2007 ◽  
Vol 30 (9) ◽  
pp. 2205-2210 ◽  
Author(s):  
I. Levinger ◽  
C. Goodman ◽  
D. L. Hare ◽  
G. Jerums ◽  
S. Selig
2009 ◽  
Vol 133 (2) ◽  
pp. 281-283 ◽  
Author(s):  
Itamar Levinger ◽  
Craig Goodman ◽  
David L. Hare ◽  
George Jerums ◽  
Steve Selig

2015 ◽  
Vol 23 (2) ◽  
pp. 101-112 ◽  
Author(s):  
Laisa Teleni ◽  
Raymond J Chan ◽  
Alexandre Chan ◽  
Elisabeth A Isenring ◽  
Ian Vela ◽  
...  

Men receiving androgen deprivation therapy (ADT) for prostate cancer (PCa) are likely to develop metabolic conditions such as diabetes, cardiovascular disease, abdominal obesity and osteoporosis. Other treatment-related side effects adversely influence quality of life (QoL) including vasomotor distress, depression, anxiety, mood swings, poor sleep quality and compromised sexual function. The objective of this study was to systematically review the nature and effects of dietary and exercise interventions on QoL, androgen deprivation symptoms and metabolic risk factors in men with PCa undergoing ADT. An electronic search of CINAHL, CENTRAL, Medline, PsychINFO and reference lists was performed to identify peer-reviewed articles published between January 2004 and December 2014 in English. Eligible study designs included randomised controlled trials (RCTs) with pre- and post-intervention data. Data extraction and assessment of methodological quality with the Cochrane approach was conducted by two independent reviewers. Seven exercise studies were identified. Exercise significantly improved QoL, but showed no effect on metabolic risk factors (weight, waist circumference, lean or fat mass, blood pressure and lipid profile). Two dietary studies were identified, both of which tested soy supplements. Soy supplementation did not improve any outcomes. No dietary counselling studies were identified. No studies evaluated androgen-deficiency symptoms (libido, erectile function, sleep quality, mood swings, depression, anxiety and bone mineral density). Evidence from RCTs indicates that exercise enhances health- and disease-specific QoL in men with PCa undergoing ADT. Further studies are required to evaluate the effect of exercise and dietary interventions on QoL, androgen deprivation symptoms and metabolic risk factors in this cohort.


2012 ◽  
Vol 3 (7) ◽  
pp. 226-231 ◽  
Author(s):  
Vaiyapuri Anandh ◽  
◽  
Ivor Peter D’SA Ivor Peter D’SA ◽  
Jagatheesan Alagesan

2021 ◽  
Author(s):  
Dmitry Rozenberg ◽  
Daniel Santa Mina ◽  
Sahar Nourouzpour ◽  
Encarna Camacho Perez ◽  
Brooke Stewart ◽  
...  

BACKGROUND Post-transplant metabolic syndrome (PTMS) is a common contributor to morbidity and mortality in solid organ transplant recipients in the late post-transplant period (≥ 1-year). Patients diagnosed with PTMS are at higher risk of cardiovascular disease and frequently experience decreased physical function and health-related quality of life (HRQL). Studies in the early post-transplant period (< 1-year) have shown the benefits of facility-based exercise training on physical function and HRQL, but have not evaluated the effects on metabolic risk factors. It remains unclear whether home-based exercise programs are feasible and can be sustained with sufficient adherence and exercise dose to have effects on PTMS. This protocol outlines the methodology of a randomized controlled trial of a partly-supervised home-based exercise program in lung (LTx) and liver (OLT) transplant recipients. OBJECTIVE 1) To evaluate the feasibility (i.e. recruitment rate, program adherence, attrition, safety, and participant satisfaction) of a 12-week individualized, home-based aerobic and resistance training program in LTx and OLT recipients initiated 12 to 18 months post-transplant; and 2) to assess estimates of intervention efficacy on metabolic risk factors, self-efficacy for exercise, and HRQL. METHODS 20 LTx and 20 OLT recipients with two or more cardio-metabolic risk factors at 12-18 months post-transplant will be randomized to an intervention group (home-based exercise training) or a control group. The intervention group will receive an individualized exercise prescription comprising aerobic and resistance training 3-5 times per week for 12 weeks. Participants will meet with a qualified exercise professional weekly (via videoconference) to guide exercise progression, provide support, and promote exercise self-efficacy. Participants in both study groups will receive one counselling session on healthy eating with a dietitian at the beginning of the intervention. For the primary aim, feasibility will be assessed through recruitment rate, program adherence, satisfaction, attrition, and safety. Secondary outcomes will be measured at baseline and 12-weeks, and include assessments of metabolic risk factors (i.e. insulin resistance, abdominal obesity, blood pressure, and cholesterol), HRQL, and exercise self-efficacy. Descriptive statistics will be used to summarize program feasibility and effect estimates (means and 95% confidence interval) for sample size calculations in future trials. RESULTS Enrollment for this study started in July 2021. It is estimated that the study period will be 18 months with data collection completed by December 2022. CONCLUSIONS A partly-supervised home-based, individually tailored exercise program that promotes aerobic and resistance training and exercise self-efficacy may prove to be an important intervention for improving the metabolic profile of LTx and OLT recipients with cardio-metabolic risk factors. Thus, characterizing the feasibility and effect estimates of home-based exercise constitutes the first step in the development of future clinical trials designed to reduce the high morbidity associated with PTMS. CLINICALTRIAL https://clinicaltrials.gov/ct2/show/NCT04965142


Author(s):  
Giovanna Arevalo ◽  
Dionei Ramos ◽  
Fábio Lira ◽  
Bruna Silva ◽  
Fabiano Lima ◽  
...  

2017 ◽  
Vol 63 (11) ◽  
pp. 978-987
Author(s):  
Ariella Sebastião Mangia ◽  
Nara Lisiane de Oliveira Coqueiro ◽  
Fernanda Cabral Azevedo ◽  
Hiago Tomaz da Silva Araujo ◽  
Elizandra de Oliveira Amorim ◽  
...  

Summary Objective: To correlate physical activity level (PAL), functional capacity and psychological state with quality of life (QoL) in cancer patients undergoing chemotherapy (CT). Method: Observational cohort study. Patients (n=121) with any primary cancer site with indications of chemotherapy with palliative or curative intent were evaluated at three moments: 1) patient admission (week 0), before chemotherapy; 2) week 8; 3) end of CT. Data were collected regarding QoL, PAL, clinical data, functional capacity (short walking distance test, sitting-rising test, isometric manual gripping force), and anxiety and depression tests. Results: There was significant improvement at the end of CT for: level of physical activity; walk test (> 500 meters); sitting-rising test (> 20x). There was a significant reduction in the prevalence of moderate/severe depression. The prevalence of high QoL showed a significant increase in evaluation 3 (42.4% vs. 40.0% vs. 59.2%, p=0.02). Education up to high school level, low PAL, walking < 300 meters, sitting and rising < 20 times, having depression (moderate to severe) and QoL that was not high at the start of treatment (week 0) all proved to be risk factors for low quality of life at week 16. Conversely, early staging, curative intent chemotherapy and low-grade symptoms were shown to be protective factors. Conclusion: Performing less than 20 movements in the sitting-rising test and low PAL at the start of chemotherapy represent independent risk factors for low quality of life at the end of chemotherapy.


2010 ◽  
Vol 28 ◽  
pp. e374
Author(s):  
T Póvoa ◽  
P Jardim ◽  
A Lima ◽  
C Salgado ◽  
C Souza ◽  
...  

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