Modeling Chronic Glycemic Exposure Variables as Correlates and Predictors of Microvascular Complications of Diabetes: Response to Dyck et al.

Diabetes Care ◽  
2007 ◽  
Vol 30 (2) ◽  
pp. 448-448
Author(s):  
T. J. Orchard ◽  
T. Costacou ◽  
R. G. Miller ◽  
C. T. Prince ◽  
G. Pambianco
Keyword(s):  
Microvascular Complications ◽  
Complications Of Diabetes

scholarly journals Prevention of Microvascular Complications of Diabetes

2021 ◽  
Vol 50 (3) ◽  
pp. 431-455
Author(s):  
Winston Crasto ◽  
Vinod Patel ◽  
Melanie J. Davies ◽  
Kamlesh Khunti
Keyword(s):  
Microvascular Complications ◽  
Complications Of Diabetes

scholarly journals Chronic Microvascular Complications in Prediabetic States—An Overview

2020 ◽  
Vol 9 (10) ◽  
pp. 3289
Author(s):  
Angelika Baranowska-Jurkun ◽  
Wojciech Matuszewski ◽  
Elżbieta Bandurska-Stankiewicz
Keyword(s):  
Risk Factor ◽  
Glucose Metabolism ◽  
Microvascular Complications ◽  
Current Data ◽  
Chronic Complications ◽  
Prediabetic State ◽  
Complications Of Diabetes ◽  
Glucose Levels ◽  
Abnormal Glucose Metabolism

A prediabetic state is a major risk factor for the development of diabetes, and, because of an identical pathophysiological background of both conditions, their prevalence increases parallelly and equally fast. Long-term hyperglycemia is the main cause inducing chronic complications of diabetes, yet the range of glucose levels at which they start has not been yet unequivocally determined. The current data show that chronic microvascular complications of diabetes can be observed in patients with abnormal glucose metabolism in whom glycaemia is higher than optimal but below diagnostic criteria for diabetes. Prediabetes is a heterogenous nosological unit in which particular types are differently characterized and show different correlations with particular kinds of complications. Analysis of the latest research results shows the need to continue studies in a larger population and can imply the need to verify the currently employed criteria of diagnosing diabetes and chronic complications of diabetes in people with prediabetes.

Risk Factors for Microvascular Complications of Diabetes Among South Indian Subjects with Type 2 Diabetes—The Chennai Urban Rural Epidemiology Study (CURES) Eye Study-5

2010 ◽  
Vol 12 (10) ◽  
pp. 755-761 ◽  
Author(s):  
Rajendra Pradeepa ◽  
Ranjit Mohan Anjana ◽  
Ranjit Unnikrishnan ◽  
Anbazaghan Ganesan ◽  
Vishwanathan Mohan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Microvascular Complications ◽  
Epidemiology Study ◽  
Complications Of Diabetes ◽  
South Indian ◽  
Urban Rural

scholarly journals Dyslipidemia, Diabetes and Atherosclerosis: Role of Inflammation and ROS-Redox-Sensitive Factors

Biomedicines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1602
Author(s):  
Elham Hasheminasabgorji ◽  
Jay C. Jha
Keyword(s):  
Oxidative Stress ◽  
Microvascular Complications ◽  
Vascular Complications ◽  
Premature Mortality ◽  
Organ Damage ◽  
Lipid Lowering ◽  
Related Factors ◽  
Complications Of Diabetes ◽  
Chronic Hyperglycemia ◽  
And Oxidative Stress

The prevalence of diabetes is growing at an alarming rate with increased disability, morbidity, and often premature mortality because of the various complications of this disorder. Chronic hyperglycemia, dyslipidemia, and other metabolic alterations lead to the development and progression of macro- and microvascular complications of diabetes including cardiovascular, retinal and kidney disease. Despite advances in glucose and lipid lowering treatments, a large number of diabetic individuals develop one or more types of these complications, ultimately leading to end-organ damage over the time. Atherosclerosis is the major macro-vascular complications of diabetes and the primary underlying cause of cardiovascular disease (CVD) posing heavy burden on the health care system. In this review, we discuss the involvement of dyslipidemia in the progression of atherosclerosis by activating the pro-inflammatory cytokines and oxidative stress-related factors. In addition, we also provide information on various pharmacological agents that provides protection against diabetic atherosclerosis by reducing inflammation and oxidative stress.

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