<b>Background: </b>Advances in continuous
glucose monitoring (CGM) have transformed ambulatory diabetes management. Until
recently, inpatient use of CGM has remained investigational with limited data
on its accuracy in the hospital setting.
<p><b>Methods: </b>To analyze the
accuracy of Dexcom G6 CGM,<b> </b>we compared retrospective matched-pair CGM
and capillary point-of-care (POC) glucose data from three inpatient CGM studies
(two interventional and one observational) in general medicine and surgery
patients with diabetes treated with insulin. Analysis of accuracy metrics
included mean absolute relative difference (MARD), median absolute relative difference
(ARD), and proportion of CGM values within ±15, 20 and 30% or ±15, 20 and 30
mg/dL of POC reference values for blood glucose >100 mg/dL or ≤100 mg/dL,
respectively (?/15, /20, 0/30). Clinical reliability was assessed using
Clarke error grid analyses.</p>
<p><b>Results: </b>A total of 218
patients were included (96% with type 2 diabetes) with a mean age of 60.6 ±
12 years.
The overall MARD (n=4,067 matched glucose pairs) was 12.8%
and median ARD was 10.1% [IQR 4.6, 17.6]. The proportion of readings meeting
?/15, /20 and 0/30 criteria were 68.7, 81.7, and 93.8%. Clarke error
grid analysis showed 98.7% of all values in zones A+B. MARD and median ARD were higher in
hypoglycemia (<70mg/dL) and severe anemia (hemoglobin <7g/dL).</p>
<p><b>Conclusion: </b>Our results
indicate that CGM technology is a reliable tool for hospital use and may help
improve glucose monitoring in non-critically ill hospitalized patients with
diabetes. </p>
Accuracy of Dexcom G6 Continuous Glucose Monitoring in Non-Critically Ill Hospitalized Patients with Diabetes