Beneficial Effects of Tamoxifen Treatment in Type 1 Diabetes

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2155-P
Author(s):  
JUAN ZHENG ◽  
MOHAMMAD ISHRAQ ZAFAR ◽  
LULU CHEN ◽  
XIN GUO ◽  
XIAOMING LI
Keyword(s):  
Type 1 Diabetes ◽  
Tamoxifen Treatment ◽  
Beneficial Effects

BENEFICIAL EFFECTS OF CONTINUOUS SUBCUTANEOUS INSULIN INFUSION IN OLDER PATIENTS WITH LONG-STANDING TYPE 1 DIABETES

2001 ◽  
Vol 7 (5) ◽  
pp. 364-369 ◽  
Author(s):  
Ali A. Rizvi ◽  
Robin Petry ◽  
Mary Beth Arnold ◽  
Mikai Chakraborty ◽  
Mikai Chakraborty
Keyword(s):  
Type 1 Diabetes ◽  
Older Patients ◽  
Continuous Subcutaneous Insulin Infusion ◽  
Insulin Infusion ◽  
Subcutaneous Insulin ◽  
Beneficial Effects

scholarly journals C-Peptide Exerts Beneficial Effects on Myocardial Blood Flow and Function in Patients With Type 1 Diabetes

Diabetes ◽  
2002 ◽  
Vol 51 (10) ◽  
pp. 3077-3082 ◽  
Author(s):  
A. Hansen ◽  
B.-L. Johansson ◽  
J. Wahren ◽  
H. von Bibra
Keyword(s):  
Blood Flow ◽  
Type 1 Diabetes ◽  
Myocardial Blood Flow ◽  
C Peptide ◽  
Beneficial Effects ◽  
And Function

scholarly journals Current Evidence on the Efficacy of Gluten-Free Diets in Multiple Sclerosis, Psoriasis, Type 1 Diabetes and Autoimmune Thyroid Diseases

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2316
Author(s):  
Moschoula Passali ◽  
Knud Josefsen ◽  
Jette Lautrup Frederiksen ◽  
Julie Christine Antvorskov
Keyword(s):  
Multiple Sclerosis ◽  
Type 1 Diabetes ◽  
Thyroid Diseases ◽  
Current Evidence ◽  
Gluten Free ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Beneficial Effects ◽  
Gliadin Antibodies

In this review, we summarize the clinical data addressing a potential role for gluten in multiple sclerosis (MS), psoriasis, type 1 diabetes (T1D) and autoimmune thyroid diseases (ATDs). Furthermore, data on the prevalence of celiac disease (CD) and gluten-related antibodies in the above patient groups are presented. Adequately powered and properly controlled intervention trials investigating the effects of a gluten-free diet (GFD) in non-celiac patients with MS, psoriasis, T1D or ATDs are lacking. Only one clinical trial has studied the effects of a GFD among patients with MS. The trial found significant results, but it is subject to major methodological limitations. A few publications have found beneficial effects of a GFD in a subgroup of patients with psoriasis that were seropositive for anti-gliadin or deamidated gliadin antibodies, but no effects were seen among seronegative patients. Studies on the role of gluten in T1D are contradictive, however, it seems likely that a GFD may contribute to normalizing metabolic control without affecting levels of islet autoantibodies. Lastly, the effects of a GFD in non-celiac patients with ATDs have not been studied yet, but some publications report that thyroid-related antibodies respond to a GFD in patients with concomitant CD and ATDs. Overall, there is currently not enough evidence to recommend a GFD to non-celiac patients with MS, psoriasis, ATDs or T1D.

Once-weekly supervised combined training improves neurocognitive and psychobehavioral outcomes in young patients with type 1 diabetes mellitus

2019 ◽  
Vol 32 (12) ◽  
pp. 1341-1350 ◽  
Author(s):  
Junghwan Suh ◽  
Han Saem Choi ◽  
Ahreum Kwon ◽  
Hyun Wook Chae ◽  
Soyong Eom ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Resistance Exercise ◽  
Type 1 Diabetes Mellitus ◽  
Exercise Program ◽  
Exercise Group ◽  
Control Group ◽  
Diabetic Patients ◽  
Beneficial Effects

Abstract Background Previous studies investigating the beneficial effects of exercise in type 1 diabetes mellitus (T1DM) are relatively insufficient compared to studies on type 2 diabetes mellitus (T2DM), due to the fear of hypoglycemia. Recently, several researchers have reported that combined aerobic and resistance exercise prevents hypoglycemia during and after exercise. Furthermore, exercise has been shown to have beneficial effects on the psychological status of patients with various diseases. The aim of this study was to evaluate the effect of combined aerobic and resistance exercise in adolescents with T1DM. Methods Thirty-five type 1 diabetic patients were enrolled, and subjects were divided into either an exercise group or a control group. Thirty patients (20 patients in the exercise group, 10 patients in the control group) completed the study. The exercise program was performed for 1 h at a time, once a week, for 12 weeks. Study parameters were evaluated at baseline and 3 months after baseline evaluation. Results Combined aerobic and resistance exercise better controlled the body mass index (BMI), and also improved maximum muscular strength and maximum exercise intensity. On psychological tests, subjects’ attention and quality of life showed improving tendency, while their stress and behavioral problems diminished. The number of exercise events increased in the training group, while the daily total insulin dose and glycated hemoglobin (HbA1c) level showed no significant changes. Conclusions A 12-week structured exercise program consisting of aerobic and resistance exercises improves cardiovascular, neurocognitive and psychobehavioral functions, and positively helps lifestyle modification in patients with T1DM.

Transitory Beneficial Effects of Professional Continuous Glucose Monitoring on the Metabolic Control of Patients with Type 1 Diabetes

2014 ◽  
Vol 16 (4) ◽  
pp. 219-223 ◽  
Author(s):  
Ioana Patrascioiu ◽  
Carmen Quirós ◽  
Paola Ríos ◽  
Montserrat Ruíz ◽  
Rosa Mayordomo ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Metabolic Control ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Beneficial Effects

Beneficial effects of physical exercise for β‐cell maintenance in a Type 1 Diabetes mellitus animal model

2021 ◽  
Author(s):  
Catharina Barros Pimentel Villaça ◽  
Carolina Cavalcante Paula ◽  
Caroline Cruz Oliveira ◽  
Eloisa Aparecida Vilas‐Boas ◽  
Junia Carolina Santos‐Silva ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Animal Model ◽  
Type 1 Diabetes ◽  
Physical Exercise ◽  
Type 1 Diabetes Mellitus ◽  
Β Cell ◽  
Beneficial Effects ◽  
Cell Maintenance

scholarly journals Performance of the Eversense versus the Free Style Libre Flash glucose monitor during exercise and normal daily activities in subjects with type 1 diabetes mellitus

2020 ◽  
Vol 8 (1) ◽  
pp. e001193 ◽  
Author(s):  
Marion Fokkert ◽  
Peter R van Dijk ◽  
Mireille A Edens ◽  
Alberto Díez Hernández ◽  
Robbert Slingerland ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Glucose Oxidase ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Daily Activities ◽  
Glucose Measurement ◽  
Beneficial Effects ◽  
Intensive Exercise ◽  
Interstitial Glucose

IntroductionAccurate blood glucose measurements are important in persons with diabetes during normal daily activities (NDA), even more so during exercise. We aimed to investigate the performance of fluorescence sensor-based and glucose oxidase-based interstitial glucose measurement during (intensive) exercise and NDA.Research design and methodsProspective, observational study in 23 persons with type 1 diabetes when mountain biking for 6 days, followed by 6 days of NDA. Readings of the Eversense (fluorescence-based continuous glucose monitoring (CGM); subcutaneously implanted) and of the Free Style Libre (FSL; glucose oxidase-based flash glucose monitoring (FGM); transcutaneously placed) were compared with capillary glucose levels (Free Style Libre Precision NeoPro strip (FSLCstrip)).ResultsMean average differences (MAD) and mean average relative differences (MARD) were significantly different when comparing exercise with NDA (reference FSLCstrip); Eversense MAD 25±19 vs 17±6 mg/dL (p<0.001); MARD 17±6 vs 13%±6% (p<0.01) and FSL MAD 32±17 vs 18±8 mg/dL (p<0.01); MARD 20±7 vs 12%±5% (p<0.001).When analyzing the data according to the Integrated Continuous Glucose Monitoring Approvals (class II–510(K) guidelines), the overall performance of interstitial glucose readings within 20% of the FSLCstrip during exercise compared with NDA was 69% vs 81% for the Eversense and 59% vs 83% for the FSL, respectively. Within 15% of the FSLCstrip was 59% vs 70% for the Eversense and 46% vs 71% for the FSL.ConclusionsDuring exercise, both fluorescence and glucose oxidase-based interstitial glucose measurements (using Eversense and FSL sensors) were less accurate compared with measurements during NDA. Even when acknowledging the beneficial effects of CGM or FGM, users should be aware of the risk of diminished accuracy of interstitial glucose readings during (intensive) exercise.

scholarly journals Potential beneficial effects of a gluten-free diet in newly diagnosed children with type 1 diabetes: a pilot study

SpringerPlus ◽  
2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Jannet Svensson ◽  
Stine Møller Sildorf ◽  
Christian B. Pipper ◽  
Julie N. Kyvsgaard ◽  
Julie Bøjstrup ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Pilot Study ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Newly Diagnosed ◽  
Beneficial Effects

Histological effects of pharmacologically active human bile acid nano/micro-particles in Type-1 diabetes

2020 ◽  
Vol 11 (3) ◽  
pp. 157-171
Author(s):  
Sangeetha Mathavan ◽  
Corina M Ionescu ◽  
Bozica Kovacevic ◽  
Momir Mikov ◽  
Svetlana Golocorbin-Kon ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Bile Acid ◽  
Drug Formulation ◽  
Human Bile ◽  
Beneficial Effects ◽  
Micro Particles ◽  
Anti Inflammatory ◽  
Pharmacologically Active

Aim: Gliclazide (G) is a drug prescribed for Type 2 diabetics, although recent studies suggest it has desirable effects in both types of diabetes, Type 1 diabetes and Type 2 diabetes. G has an inconsistent absorption due to poor formulation and bile acids (BAs) have shown significant promise in drug formulation optimization. Hence, the study aimed to examine G effects on histopathological, anti-inflammatory and antidiabetic effects when encapsulated with BAs. Materials & methods: Rats were randomized into eight groups, of which seven were made Type 1 diabetes and treated with various BA-based treatments. Tissue histopathology, inflammation and the bile acid profile were analyzed. Results & conclusion: G capsules showed no histological but the most anti-inflammatory effects, which suggest significant beneficial effects in diabetes treatment.

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