scholarly journals Interferon-γ Limits Diabetogenic CD8 + T-Cell Effector Responses in Type 1 Diabetes

Diabetes ◽  
2016 ◽  
Vol 66 (3) ◽  
pp. 710-721 ◽  
Author(s):  
John P. Driver ◽  
Jeremy J. Racine ◽  
Cheng Ye ◽  
Deanna J. Lamont ◽  
Brittney N. Newby ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
T Cell ◽  
Cd8 T Cell ◽  
Interferon Γ ◽  
Cell Effector

scholarly journals Type 1 diabetes progression is associated with loss of CD3+CD56+ regulatory T cells that control CD8+ T-cell effector functions

2020 ◽  
Vol 2 (2) ◽  
pp. 142-152 ◽  
Author(s):  
Giuseppe Terrazzano ◽  
Sara Bruzzaniti ◽  
Valentina Rubino ◽  
Marianna Santopaolo ◽  
Anna Teresa Palatucci ◽  
...  
Keyword(s):  
T Cells ◽  
Type 1 Diabetes ◽  
T Cell ◽  
Regulatory T Cells ◽  
Cd8 T Cell ◽  
Effector Functions ◽  
Diabetes Progression ◽  
Cell Effector

scholarly journals Peripheral autoreactive CD8 T‐cell frequencies are too variable to be a reliable predictor of disease progression of human type 1 diabetes

2021 ◽  
Vol 10 (7) ◽  
Author(s):  
Johnna D Wesley ◽  
Susanne Pfeiffer ◽  
Darius Schneider ◽  
David Friedrich ◽  
Nikole Perdue ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
T Cell ◽  
Disease Progression ◽  
Cd8 T Cell ◽  
Human Type ◽  
Reliable Predictor ◽  
Human Type 1 Diabetes

scholarly journals CD5 expressing CD8 + T cell subsets differ between children with Type 1 diabetes and controls

2021 ◽  
Author(s):  
Josefine Wadenpohl ◽  
Julia Seyfarth ◽  
Paul Hehenkamp ◽  
Maximilian Hoffmann ◽  
Sebastian Kummer ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
T Cell ◽  
Cd8 T Cell ◽  
T Cell Subsets

scholarly journals The Frequency and Immunodominance of Islet-Specific CD8+ T-cell Responses Change after Type 1 Diabetes Diagnosis and Treatment

Diabetes ◽  
2008 ◽  
Vol 57 (5) ◽  
pp. 1312-1320 ◽  
Author(s):  
E. Martinuzzi ◽  
G. Novelli ◽  
M. Scotto ◽  
P. Blancou ◽  
J.-M. Bach ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
T Cell ◽  
T Cell Responses ◽  
Cd8 T Cell ◽  
Diagnosis And Treatment ◽  
Diabetes Diagnosis ◽  
Cell Responses

High-throughput Screening for CD8+ T Cell Epitopes Targeted in Type 1 Diabetes

2010 ◽  
Vol 135 ◽  
pp. S19
Author(s):  
Brian Hondowicz ◽  
Katharine Schwedhelm ◽  
Arnold Kas ◽  
Michael Tasch ◽  
Nirasha Ramchurren ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
T Cell ◽  
High Throughput ◽  
High Throughput Screening ◽  
Cd8 T Cell ◽  
T Cell Epitopes

An autoimmune stem-like CD8 T cell population drives type 1 diabetes

Nature ◽  
2021 ◽  
Author(s):  
Sofia V. Gearty ◽  
Friederike Dündar ◽  
Paul Zumbo ◽  
Gabriel Espinosa-Carrasco ◽  
Mojdeh Shakiba ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
T Cell ◽  
Cell Population ◽  
Cd8 T Cell

SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes☆

2006 ◽  
Vol 27 (3) ◽  
pp. 166-173 ◽  
Author(s):  
A BARRAL ◽  
H THOMAS ◽  
E LING ◽  
R DARWICHE ◽  
E RODRIGO ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
T Cell ◽  
Cd8 T Cell

Perforin facilitates beta cell killing and regulates autoreactive CD8 + T‐cell responses to antigen in mouse models of type 1 diabetes

2015 ◽  
Vol 94 (4) ◽  
pp. 334-341 ◽  
Author(s):  
Prerak Trivedi ◽  
Kate L Graham ◽  
Balasubramaninan Krishnamurthy ◽  
Stacey Fynch ◽  
Robyn M Slattery ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
T Cell ◽  
Beta Cell ◽  
Mouse Models ◽  
T Cell Responses ◽  
Cd8 T Cell ◽  
Cell Killing ◽  
Cell Responses
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