scholarly journals Hypothyroidism Impairs Human Stem Cell–Derived Pancreatic Progenitor Cell Maturation in Mice

Diabetes ◽  
2016 ◽  
Vol 65 (5) ◽  
pp. 1297-1309 ◽  
Author(s):  
Jennifer E. Bruin ◽  
Nelly Saber ◽  
Shannon O’Dwyer ◽  
Jessica K. Fox ◽  
Majid Mojibian ◽  
...  
Keyword(s):  
Stem Cell ◽  
Progenitor Cell ◽  
Cell Maturation ◽  
Human Stem Cell ◽  
Pancreatic Progenitor ◽  
Pancreatic Progenitor Cell

PPDPF impacts pancreatic progenitor cell formation derived from human pluripotent stem cell

2018 ◽  
Vol 56 (08) ◽  
pp. e234-e234
Author(s):  
M Breunig ◽  
M Hohwieler ◽  
T Seufferlein ◽  
J Glöckner ◽  
S Liebau ◽  
...  
Keyword(s):  
Stem Cell ◽  
Pluripotent Stem Cell ◽  
Progenitor Cell ◽  
Cell Formation ◽  
Human Pluripotent Stem Cell ◽  
Pancreatic Progenitor ◽  
Pancreatic Progenitor Cell

scholarly journals Pancreatic progenitor-derived hepatocytes are viable and functional in a 3D high density bioreactor culture system

2016 ◽  
Vol 5 (1) ◽  
pp. 278-290 ◽  
Author(s):  
M. Richter ◽  
E. A. Fairhall ◽  
S. A. Hoffmann ◽  
S. Tröbs ◽  
F. Knöspel ◽  
...  
Keyword(s):  
Drug Metabolism ◽  
Cell Line ◽  
Culture System ◽  
Progenitor Cell ◽  
High Density ◽  
Bioreactor Culture ◽  
Pancreatic Progenitor ◽  
Pancreatic Progenitor Cell ◽  
System P ◽  
Progenitor Cell Line

The rat pancreatic progenitor cell line B-13 is of interest for research on drug metabolism and toxicity since the cells trans-differentiate into functional hepatocyte-like cells (B-13/H) when treated with glucocorticoids.

scholarly journals Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice

2015 ◽  
Vol 5 (6) ◽  
pp. 1081-1096 ◽  
Author(s):  
Jennifer E. Bruin ◽  
Ali Asadi ◽  
Jessica K. Fox ◽  
Suheda Erener ◽  
Alireza Rezania ◽  
...  
Keyword(s):  
Stem Cell ◽  
Progenitor Cells ◽  
Human Stem Cell ◽  
Pancreatic Progenitor ◽  
Pancreatic Progenitor Cells ◽  
Insulin Secreting Cells

scholarly journals The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival

Development ◽  
2017 ◽  
Vol 145 (1) ◽  
pp. dev154468 ◽  
Author(s):  
Stefan Norlin ◽  
Vishal Parekh ◽  
Helena Edlund
Keyword(s):  
Atpase Activity ◽  
Cell Survival ◽  
Progenitor Cell ◽  
Pancreatic Progenitor ◽  
Pancreatic Progenitor Cell

scholarly journals Generation of hepatocytes expressing functional cytochromes P450 from a pancreatic progenitor cell line in vitro

2003 ◽  
Vol 370 (3) ◽  
pp. 763-769 ◽  
Author(s):  
Carylyn J. MAREK ◽  
Gary A. CAMERON ◽  
Lucy J. ELRICK ◽  
Gabrielle M. HAWKSWORTH ◽  
Matthew C. WRIGHT
Keyword(s):  
Cell Line ◽  
Progenitor Cell ◽  
Cytochromes P450 ◽  
Glucocorticoid Treatment ◽  
Pancreatic Cell ◽  
Pancreatic Progenitor ◽  
Albumin Gene ◽  
Pancreatic Progenitor Cell ◽  
Progenitor Cell Line

The proliferating AR42J-B13 pancreatic cell line is known to respond to glucocorticoid treatment by producing foci of cells that express the liver-specific albumin gene. We demonstrate that this cell line also expresses liver-specific or liver-enriched functional cytochrome P450 proteins when stimulated to trans-differentiate into hepatocytes by glucocorticoid. These data suggest that this cell line has an unusual ability to trans-differentiate into functional hepatocytes and that it could be possible to generate a limitless supply of functional hepatocyte-like cells in vitro.

scholarly journals SOX9 is required for maintenance of the pancreatic progenitor cell pool

2007 ◽  
Vol 104 (6) ◽  
pp. 1865-1870 ◽  
Author(s):  
P. A. Seymour ◽  
K. K. Freude ◽  
M. N. Tran ◽  
E. E. Mayes ◽  
J. Jensen ◽  
...  
Keyword(s):  
Progenitor Cell ◽  
Pancreatic Progenitor ◽  
Pancreatic Progenitor Cell ◽  
Cell Pool ◽  
Progenitor Cell Pool
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