scholarly journals Vasohibin-1, a Negative Feedback Regulator of Angiogenesis, Ameliorates Renal Alterations in a Mouse Model of Diabetic Nephropathy

Diabetes ◽  
2009 ◽  
Vol 58 (10) ◽  
pp. 2365-2375 ◽  
Author(s):  
T. Nasu ◽  
Y. Maeshima ◽  
M. Kinomura ◽  
K. Hirokoshi-Kawahara ◽  
K. Tanabe ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Mouse Model ◽  
Negative Feedback ◽  
Feedback Regulator

scholarly journals Vasohibin-1, a negative feedback regulator of angiogenesis, ameliorates renal alterations in a mouse model of diabetic nephropathy

2011 ◽  
Vol 123 (1) ◽  
pp. 19-25
Author(s):  
Tatsuyo Nasu ◽  
Yohei Maeshima ◽  
Masaru Kinomura ◽  
Kumiko Hirokoshi-Kawahara ◽  
Katsuyuki Tanabe ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Mouse Model ◽  
Negative Feedback ◽  
Feedback Regulator

483-P: Key Biochemical and Histopathological Markers of Diabetic Nephropathy Correlate with Hypertension in the Renin-AAV Uninephrectomized db/db Mouse Model

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 483-P
Author(s):  
METTE V. ØSTERGAARD ◽  
IDA R. SØRENSEN ◽  
ANNEMARIE A. PEDERSEN ◽  
THOMAS SECHER ◽  
FREDERIKKE E. SEMBACH ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Mouse Model

Thrombin induces IL-10 production in microglia as a negative feedback regulator of TNF-α release

Neuroreport ◽  
2002 ◽  
Vol 13 (6) ◽  
pp. 849-852 ◽  
Author(s):  
Kyung You Kim ◽  
Min Young Kim ◽  
Hee Seung Choi ◽  
Byung Kwan Jin ◽  
Seung Up Kim ◽  
...  
Keyword(s):  
Negative Feedback ◽  
Tnf Α ◽  
Feedback Regulator

Diabetic kidney disease in thedb/dbmouse

2003 ◽  
Vol 284 (6) ◽  
pp. F1138-F1144 ◽  
Author(s):  
Kumar Sharma ◽  
Peter McCue ◽  
Stephen R. Dunn
Keyword(s):  
Diabetic Nephropathy ◽  
Kidney Disease ◽  
Mouse Model ◽  
Renal Disease ◽  
Mouse Models ◽  
Diabetic Kidney Disease ◽  
Diabetic Kidney ◽  
Matrix Expansion ◽  
Stage Renal Disease ◽  
End Stage

Diabetic nephropathy is increasing in incidence and is now the number one cause of end-stage renal disease in the industrialized world. To gain insight into the genetic susceptibility and pathophysiology of diabetic nephropathy, an appropriate mouse model of diabetic nephropathy would be critical. A large number of mouse models of diabetes have been identified and their kidney disease characterized to various degrees. Perhaps the best characterized and most intensively investigated model is the db/ db mouse. Because this model appears to exhibit the most consistent and robust increase in albuminuria and mesangial matrix expansion, it has been used as a model of progressive diabetic renal disease. In this review, we present the findings from various studies on the renal pathology of the db/ db mouse model of diabetes in the context of human diabetic nephropathy. Furthermore, we discuss shortfalls of assessing functional renal disease in mouse models of diabetic kidney disease.

scholarly journals Odd skipped related 1is a negative feedback regulator of nodal-induced endoderm development

2014 ◽  
Vol 243 (12) ◽  
pp. 1571-1580 ◽  
Author(s):  
Alexandra V. Terashima ◽  
Sudha P. Mudumana ◽  
Iain A. Drummond
Keyword(s):  
Negative Feedback ◽  
Endoderm Development ◽  
Feedback Regulator

FLU, a negative feedback regulator of tetrapyrrole biosynthesis, is physically linked to the final steps of the Mg++ -branch of this pathway

FEBS Letters ◽  
2011 ◽  
Vol 586 (3) ◽  
pp. 211-216 ◽  
Author(s):  
Dominika Kauss ◽  
Sylvain Bischof ◽  
Sandro Steiner ◽  
Klaus Apel ◽  
Rasa Meskauskiene
Keyword(s):  
Negative Feedback ◽  
Tetrapyrrole Biosynthesis ◽  
Feedback Regulator

Pathogenesis and Treatment of Type 2 Diabetic Nephropathy: Lessons from the Spontaneous KK/Ta Mouse Model

2005 ◽  
Vol 1 (3) ◽  
pp. 281-286 ◽  
Author(s):  
Yasuhiko Tomino ◽  
Mitsuo Tanimoto ◽  
Toshihide Shike ◽  
Kenji Shiina ◽  
Qiuling Fan ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Mouse Model ◽  
Type 2 Diabetic
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