scholarly journals Exploring the Burden of Mealtime Insulin Dosing in Adults and Children With Type 1 Diabetes

2021 ◽  
pp. cd200117
Author(s):  
Wendy Lane ◽  
Emma Lambert ◽  
Jesso George ◽  
Naveen Rathor ◽  
Nandu Thalange
Keyword(s):  
Type 1 Diabetes ◽  
Adults And Children ◽  
Mealtime Insulin

scholarly journals Exploring the Burden of Mealtime Insulin Dosing in Adults and Children With Type 1 Diabetes

2021 ◽  
Author(s):  
Wendy Lane ◽  
Emma Lambert ◽  
Jesso George ◽  
Naveen Rathor ◽  
Nandu Thalange
Keyword(s):  
Quality Of Life ◽  
Type 1 Diabetes ◽  
Online Study ◽  
Attitudes And Behaviors ◽  
Adults And Children ◽  
Mealtime Insulin ◽  
Bolus Insulin ◽  
The Impact

Timely and accurate mealtime insulin dosing can be an ongoing challenge for people with type 1 diabetes. This multinational, online study aimed to explore attitudes and behaviors around mealtime insulin dosing and the impact of mealtime dose timing, particularly with regard to premeal dosing (15–20 minutes before a meal). Although the majority of surveyed participants (96%) recognized the importance of accurate mealtime bolus insulin dosing, only a small proportion (35%) reported being “very confident” in accurate bolus insulin estimation. Given the choice, the majority of participants would prefer to administer insulin immediately before or after a meal, as this timing would improve their quality of life.<b></b>

scholarly journals Exploring the Burden of Mealtime Insulin Dosing in Adults and Children With Type 1 Diabetes

2021 ◽  
Author(s):  
Wendy Lane ◽  
Emma Lambert ◽  
Jesso George ◽  
Naveen Rathor ◽  
Nandu Thalange
Keyword(s):  
Quality Of Life ◽  
Type 1 Diabetes ◽  
Online Study ◽  
Attitudes And Behaviors ◽  
Adults And Children ◽  
Mealtime Insulin ◽  
Bolus Insulin ◽  
The Impact

Timely and accurate mealtime insulin dosing can be an ongoing challenge for people with type 1 diabetes. This multinational, online study aimed to explore attitudes and behaviors around mealtime insulin dosing and the impact of mealtime dose timing, particularly with regard to premeal dosing (15–20 minutes before a meal). Although the majority of surveyed participants (96%) recognized the importance of accurate mealtime bolus insulin dosing, only a small proportion (35%) reported being “very confident” in accurate bolus insulin estimation. Given the choice, the majority of participants would prefer to administer insulin immediately before or after a meal, as this timing would improve their quality of life.<b></b>

Diagnostic Accuracy of Serologic Screening Tests for Celiac Disease in Asymptomatic Adults and Children with Type 1 Diabetes

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1579-P
Author(s):  
MICHELLE GOULD ◽  
FARID H. MAHMUD ◽  
ANTOINE B. CLARKE ◽  
ESTHER ASSOR ◽  
AMISH PARIKH ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Celiac Disease ◽  
Diagnostic Accuracy ◽  
Screening Tests ◽  
Adults And Children ◽  
Serologic Screening

scholarly journals Screening and Treatment Outcomes in Adults and Children with Type 1 Diabetes and Asymptomatic Celiac Disease: The CD-DIET Study

2020 ◽  
Author(s):  
Farid H. Mahmud ◽  
Antoine B.M. Clarke ◽  
Kariym C. Joachim ◽  
Esther Assor ◽  
Charlotte McDonald ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Celiac Disease ◽  
Glucose Monitoring ◽  
Gluten Free ◽  
Asymptomatic Patients ◽  
Adults And Children ◽  
Diet Study ◽  
Glycemic Outcomes ◽  
Design And Methods

<b>Objective</b>: To describe Celiac Disease (CD) screening rates and glycemic outcomes of a gluten-free diet (GFD) in type 1 diabetes patients asymptomatic for CD. <p><b>Research Design and Methods</b>: Asymptomatic patients (8-45 years) were screened for CD. Biopsy-confirmed CD participants were randomized to GFD or gluten-containing diet (GCD) to assess changes in HbA1c and continuous glucose monitoring (CGM) over 12 months. </p> <p><b>Results</b>: Adults had higher CD-seropositivity rates than children (6.8%, 95%CI 4.9% to 8.2%, N=1298 vs. 4.7%; 95%CI 3.4% to 5.9%, N=1089, p=0.035) with lower rates of prior CD-screening (6.9% vs 44.2%, p<0.0001). 51 participants were randomized to a GFD (N=27) or GCD (N=24). No HbA1c differences were seen between groups (+0.14%, 1.5mmol/mol; 95%CI: -0.79 to 1.08; p=0.76) although greater post-prandial glucose increases (4-hr +1.5mmol/L; 95%CI: 0.4 to 2.7; p=0.014) emerged with a GFD.</p> <p><b>Conclusions</b>: CD is frequently observed in asymptomatic patients with type 1 diabetes and clinical vigilance is warranted with initiation of a GFD. </p>

scholarly journals Screening and Treatment Outcomes in Adults and Children With Type 1 Diabetes and Asymptomatic Celiac Disease: The CD-DIET Study

Diabetes Care ◽  
2020 ◽  
Vol 43 (7) ◽  
pp. 1553-1556 ◽  
Author(s):  
Farid H. Mahmud ◽  
Antoine B.M. Clarke ◽  
Kariym C. Joachim ◽  
Esther Assor ◽  
Charlotte McDonald ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Celiac Disease ◽  
Treatment Outcomes ◽  
Adults And Children ◽  
Diet Study

Serum 1,5-Anhydroglucitol Concentration as a Biomarker for Type 1 Diabetes in Adults and Children

2019 ◽  
Vol 65 (09/2019) ◽  
Author(s):  
Bruna Martins ◽  
Letícia Gomes ◽  
Kátia Boritza ◽  
Mauren Anghebem-Oliveira ◽  
Emanuel Souza ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Adults And Children

scholarly journals From 'pleasure to chemistry': the experience of carbohydrate counting with and without carbohydrate restriction for people with Type 1 diabetes

2015 ◽  
Vol 7 (4) ◽  
pp. 291 ◽  
Author(s):  
Pip Cresswell ◽  
Jeremy Krebs ◽  
Jean Gilmour ◽  
Aoife Hanna ◽  
Amber Parry-Strong
Keyword(s):  
Insulin Resistance ◽  
Type 1 Diabetes ◽  
Diabetes Mellitus Type 1 ◽  
Insulin Dosage ◽  
Daily Maximum ◽  
Carbohydrate Counting ◽  
Low Carbohydrate Diet ◽  
Low Carbohydrate ◽  
Mealtime Insulin

INTRODUCTION: Matching carbohydrate intake with insulin dosage is recommended management for people with Type 1 diabetes. However, international interest in restricted carbohydrate diets is growing. General practitioners and practice nurses need to know how to advise people with Type 1 diabetes regarding low-carbohydrate diets. This study aimed to explore the carbohydrate counting experiences of people with Type 1 diabetes in a trial with and without a diet restricted to 75 g of carbohydrate per day. METHODS: Eight participants were interviewed by focus group or interview 12 weeks after a carbohydrate counting course with individual dietary choice or the same course with information on restricted carbohydrate eating and a daily maximum intake of 75 g of carbohydrate. Data were analysed using a qualitative thematic analysis approach. FINDINGS: Themes included the need for insulin management skills, impact of the dietary experience, and need for dietary knowledge. The restricted-carbohydrate group encountered mealtime insulin resistance and difficulty managing insulin dosages when transitioning on and off the low-carbohydrate diet. The diet impacted on mood, feelings of satiety and it was reported that food changed from being 'a pleasure to chemistry'. Both groups described feeling empowered to manage their diabetes as a result of the carbohydrate counting course. CONCLUSION: Participants reported increased knowledge and challenging insulin management. The restricted-carbohydrate group reported mealtime insulin resistance and a strong dietary impact. Extra health professional support may be required, especially at dietary transition periods. More research is warranted into the reported mealtime insulin resistance. KEYWORDS: Carbohydrates; diabetes mellitus, Type 1; diabetic diet; qualitative research; self care

1058-P: The Use of Metabolic Digital Twins to Personalize Mealtime Insulin Dosing in Type 1 Diabetes Clinical Management

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1058-P
Author(s):  
TENELE A. SMITH ◽  
MARIA M. SERON ◽  
GRAHAM C. GOODWIN ◽  
ADRIAN M. MEDIOLI ◽  
BRUCE R. KING ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Clinical Management ◽  
Digital Twins ◽  
Mealtime Insulin
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