Kinetics of Periodontal Regenerative Potential on Soft Tissue Cells Grown under e-PTFE Membranes.

2001 ◽  
Vol 43 (4) ◽  
pp. 374-387
Author(s):  
Takashi Nanba
Keyword(s):  
Soft Tissue ◽  
Tissue Cells ◽  
Kinetics Of

scholarly journals Implant abutment microgrooves affect soft tissue cells response via connexin 43 pathway

2018 ◽  
Vol 29 ◽  
pp. 48-48
Author(s):  
Ludovica Parisi ◽  
Benedetta Ghezzi ◽  
Andrea Toffoli ◽  
Giulia Ghiacci ◽  
Simone Lumetti ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Connexin 43 ◽  
Implant Abutment ◽  
Tissue Cells

scholarly journals In Vitro Evaluation of the Sensitivity of a Hyaluronic Acid PEG Cross-Linked to Bovine Testes Hyaluronidase

2018 ◽  
Vol 6 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Nicola Zerbinati ◽  
Torello Lotti ◽  
Damiano Monticelli ◽  
Virginia Martina ◽  
Giovanna Cipolla ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Soft Tissue ◽  
Chemical Reaction ◽  
Time Course ◽  
Soft Tissue Augmentation ◽  
Facial Soft Tissue ◽  
Microplate Reader ◽  
Kinetics Of

Neauvia Intense is biocompatible, injectable hyaluronic acid (HA) filler PEG cross-linked for facial soft-tissue augmentation that provides volume to tissues. The aim of the present study is to evaluate the sensitivity of Neauvia Intense in hyaluronidase from bovine testes in a time-course analysis. The test is based on the colourimetric determination of the N-acetyl – D - glucosamine (NAG) released by the hyaluronidase in standardised conditions. The in vitro conditions involve the treatment of Neauvia Intense with a known concentration of the enzyme (6080U/ml). The NAG content was determined at different times to assess the kinetics of the degradation (1h, 3h, 6h, 24h, 48h, 72h, 120h, and 168h); the Ehrlich’s reagent was used for the colourimetric quantification, by the method described by Reissing and colleagues. The intensity of the violet colour developed after the chemical reaction was proportional to the NAG present in each sample. A microplate reader at 585 nm read the absorbance. The amount of NAG released by the product was proportional to the time of incubation with bovine hyaluronidase, reaching a plateau after 168 hours.

scholarly journals Kinetic Modelling of [68Ga]Ga-DOTA-Siglec-9 in Porcine Osteomyelitis and Soft Tissue Infections

Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4094 ◽  
Author(s):  
Lars Jødal ◽  
Anne Roivainen ◽  
Vesa Oikonen ◽  
Sirpa Jalkanen ◽  
Søren B. Hansen ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Hind Limb ◽  
Kinetic Modelling ◽  
Compartment Model ◽  
Cell Surface Expression ◽  
Soft Tissue Infections ◽  
Tissue Samples ◽  
Tissue Compartment ◽  
Arterial Blood ◽  
Kinetics Of

Background: [68Ga]Ga-DOTA-Siglec-9 is a positron emission tomography (PET) radioligand for vascular adhesion protein 1 (VAP-1), a protein involved in leukocyte trafficking. The tracer facilitates the imaging of inflammation and infection. Here, we studied the pharmacokinetic modelling of [68Ga]Ga-DOTA-Siglec-9 in osteomyelitis and soft tissue infections in pigs. Methods: Eight pigs with osteomyelitis and soft tissue infections in the right hind limb were dynamically PET scanned for 60 min along with arterial blood sampling. The fraction of radioactivity in the blood accounted for by the parent tracer was evaluated with radio-high-performance liquid chromatography. One- and two-tissue compartment models were used for pharmacokinetic evaluation. Post-mortem soft tissue samples from one pig were analysed with anti-VAP-1 immunofluorescence. In each analysis, the animal’s non-infected left hind limb was used as a control. Results: Tracer uptake was elevated in soft tissue infections but remained low in osteomyelitis. The kinetics of [68Ga]Ga-DOTA-Siglec-9 followed a reversible 2-tissue compartment model. The tracer metabolized quickly; however, taking this into account, produced more ambiguous results. Infected soft tissue samples showed endothelial cell surface expression of the Siglec-9 receptor VAP-1. Conclusion: The kinetics of [68Ga]Ga-DOTA-Siglec-9 uptake in porcine soft tissue infections are best described by the 2-tissue compartment model.

scholarly journals Effect of implant structured neck design on the behavior of peri‐implant soft tissue cells

2019 ◽  
Vol 30 (S19) ◽  
pp. 41-41
Author(s):  
Benjamin Lazzarotto ◽  
Laurine Marger ◽  
Mustapha Mekki ◽  
Ashot Ghuskasyan ◽  
Antonio Barone ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Tissue Cells

scholarly journals In Vitro Effects of Streptococcus oralis Biofilm on Peri-Implant Soft Tissue Cells

Cells ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 1226
Author(s):  
Alexandra Ingendoh-Tsakmakidis ◽  
Jörg Eberhard ◽  
Christine S. Falk ◽  
Meike Stiesch ◽  
Andreas Winkel
Keyword(s):  
Soft Tissue ◽  
Stress Responses ◽  
Cell Types ◽  
Cellular Damage ◽  
Streptococcus Oralis ◽  
Gingival Epithelial Cells ◽  
Tissue Cells ◽  
In Vitro Effects ◽  
Human Gingival Epithelial Cells

Human gingival epithelial cells (HGEps) and fibroblasts (HGFs) are the main cell types in peri-implant soft tissue. HGEps are constantly exposed to bacteria, but HGFs are protected by connective tissue as long as the mucosa–implant seal is intact. Streptococcus oralis is one of the commensal bacteria, is highly abundant at healthy implant sites, and might modulate soft tissue cells—as has been described for other streptococci. We have therefore investigated the effects of the S. oralis biofilm on HGEps and HGFs. HGEps or HGFs were grown separately on titanium disks and responded to challenge with S. oralis biofilm. HGFs were severely damaged after 4 h, exhibiting transcriptional inflammatory and stress responses. In contrast, challenge with S. oralis only induced a mild transcriptional inflammatory response in HGEps, without cellular damage. HGFs were more susceptible to the S. oralis biofilm than HGEps. The pro-inflammatory interleukin 6 (IL-6) was attenuated in HGFs, as was interleukin 8 (CXCL8) in HGEps. This indicates that S. oralis can actively protect tissue. In conclusion, commensal biofilms can promote homeostatic tissue protection, but only if the implant–mucosa interface is intact and HGFs are not directly exposed.

scholarly journals Soft Tissue Motion during Impacts: Their Potential Contributions to Energy Dissipation

2002 ◽  
Vol 18 (3) ◽  
pp. 231-242 ◽  
Author(s):  
Matthew T.G. Pain ◽  
John H. Challis
Keyword(s):  
Soft Tissue ◽  
Muscle Tension ◽  
Force Plate ◽  
Soft Tissue Deformation ◽  
Skin Marker ◽  
Frequency Components ◽  
Distinct Frequency ◽  
Soft Tissue Motion ◽  
Kinetics Of ◽  
Tissue Motion

The aims of this study were to quantify intrasegmental motion using an array of 28 surface-mounted markers to examine frequency and amplitude measurements of the intrasegmental motion to calculate forces and energy transfer; and to show that the underlying muscles are a major contributor to the skin marker motion. One participant performed 27 trials under three conditions in which his forearm was struck against a solid object fixed to a force plate while the locations of the markers were recorded at 240 Hz. For impacts with equal peak forces, the muscle tension significantly affected the amount of intrasegmental motion. Tensing the arm reduced the intrasegmental motion by 50%. The quadrilateral sectors defined by the markers changed in area by 11% with approximately equal motion in the vertical and horizontal direction. The maximum linear marker motion was 1.7 cm. The intrasegmental motion had distinct frequency components around 14 and 20 Hz. Soft tissue deformation could account for 70% of the energy lost from the forearm during these impacts. The study has demonstrated the important role that intrasegment soft tissue motion can have on the kinetics of an impact.

Effects of soft tissue artifacts on the calculated kinematics and kinetics of the knee during stair-ascent

2011 ◽  
Vol 44 (6) ◽  
pp. 1182-1188 ◽  
Author(s):  
Tsung-Yuan Tsai ◽  
Tung-Wu Lu ◽  
Mei-Ying Kuo ◽  
Cheng-Chung Lin
Keyword(s):  
Soft Tissue ◽  
Stair Ascent ◽  
Soft Tissue Artifacts ◽  
Kinetics Of ◽  
Kinematics And Kinetics

scholarly journals Kinetics of trace element chromium(III) in the human body

1983 ◽  
Vol 244 (4) ◽  
pp. R445-R454 ◽  
Author(s):  
T. H. Lim ◽  
T. Sargent ◽  
N. Kusubov
Keyword(s):  
Soft Tissue ◽  
Trace Element ◽  
Human Subjects ◽  
Whole Body ◽  
Nutritional Requirement ◽  
Essential Trace Element ◽  
Transfer Rates ◽  
Plasma Pool ◽  
Whole Body Counter ◽  
Kinetics Of

Chromium(III) has been reported to be an essential trace element involved in the control of glucose metabolism by insulin. We have studied the distribution and kinetics of intravenous [51Cr]chromium(III) in six human subjects using a whole-body scintillation scanner, a whole-body counter, and plasma counting. Principal concentrations were found in the liver, spleen, soft tissue, and bone. The data were fit to a model consisting of a plasma pool in equilibrium with fast (T1/2 = 0.5–12 h), medium (1–14 days), and slow (3–12 mo) compartments, and transfer rates were calculated for exchanges between compartments. Each of the imaged organs appeared to contain varying proportions of each compartment. Two patients with hemochromatosis, in which iron overload is postulated to exclude chromium transport, were found to have altered rate constants. The results should be useful in assessing the metabolism and nutritional requirement of chromium(III) in humans and its importance in disease processes such as diabetes.

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