scholarly journals Evaluation of increases in gingival blood flow caused by NaCl solutions and dentifrices containing NaCl.

Author(s):  
Satoshi TSUJITA ◽  
Yasuteru EGUCHI
1990 ◽  
Vol 39 (1) ◽  
pp. 94-104 ◽  
Author(s):  
Hiroshi Izumi ◽  
Shizuko Kuriwada ◽  
Keishiro Karita ◽  
Takashi Sasano ◽  
Daisuke Sanjo

2002 ◽  
Vol 29 (2) ◽  
pp. 103-107 ◽  
Author(s):  
Pascal Ambrosini ◽  
Sabine Cherene ◽  
Neal Miller ◽  
Michel Weissenbach ◽  
Jacques Penaud

2018 ◽  
Vol 65 (3) ◽  
pp. 168-176 ◽  
Author(s):  
Shu Tomita ◽  
Shinya Yamazaki ◽  
Kohei Togami ◽  
Hitoshi Tada ◽  
Hiroyoshi Kawaai

Dexmedetomidine (DEX) is a sedative and analgesic agent that acts via the alpha-2 adrenoreceptor and is associated with reduced anesthetic requirements, as well as attenuated blood pressure and heart rate in response to stressful events. A previous study reported that cat gingival blood flow was controlled via sympathetic alpha-adrenergic fibers involved in vasoconstriction. In the present study, experiment 1 focused on the relationship between the effects of DEX on alpha adrenoreceptors and vasoconstriction in the tissues of the oral cavity and compared the palatal mucosal blood flow (PMBF) in rabbits between general anesthesia with sevoflurane and sedation with DEX. We found that the PMBF was decreased by DEX presumably because of the vasoconstriction of oral mucosal vessels following alpha-2 adrenoreceptor stimulation by DEX. To assess if this vasoconstriction would allow decreased use of locally administered epinephrine during DEX infusion, experiment 2 in the present study monitored the serum lidocaine concentration in rabbits to compare the absorption of lidocaine without epinephrine during general anesthesia with sevoflurane and sedation with DEX. The depression of PMBF by DEX did not affect the absorption of lidocaine. We hypothesize that this is because lidocaine dilates the blood vessels, counteracting the effects of DEX. In conclusion, despite decreased palatal blood flow with DEX infusion, local anesthetics with vasoconstrictors should be used in implant and oral surgery even with administered DEX.


2001 ◽  
Vol 36 (4) ◽  
pp. 221-226 ◽  
Author(s):  
Antonios Mavropoulos ◽  
Harald Aars ◽  
Pal Brodin

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Yu Takaesu ◽  
Takashi Hanioka ◽  
Nao Suzuki ◽  
Marie Naito ◽  
Miki Ojima

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