Antepartum Complications of Pregnancy

2018 ◽  
Author(s):  
Gaea Moore

Pregnancy presents unique considerations and challenges to the critical care provider, including the physiologic adaptations to the pregnant state, recruitment and collaboration with a multidisciplinary care team, determination of fetal status, preparing for and managing cardiac arrest in pregnancy, and evaluation and management of diseases unique to pregnancy (including preeclampsia and acute fatty liver of pregnancy). This review contains 48 references, and 4 tables. Key words: acute fatty liver of pregnancy, maternal cardiac arrest, perimortem cesarean section, preeclampsia, pregnancy

Author(s):  
Sarada Mamilla ◽  
Sandhya Rani ◽  
Gayathri . ◽  
Bhavana . ◽  
Ramya Bharghavi ◽  
...  

Acute fatty liver in pregnancy is a catstrophic condition with high mortality and morbidity. Delay in managing complications would result in fatality. We present a case of 22-year-old primi, who presented to us in labor with jaundice and later developed, disseminated intravascular coagulation, Vulval haematoma, reexploration, sepsis, ARDS and cardiac arrest and death.


2012 ◽  
Vol 60 (2) ◽  
pp. 183-190 ◽  
Author(s):  
Michael A. Horberg ◽  
Leo B. Hurley ◽  
William J. Towner ◽  
Michael W. Allerton ◽  
Beth T. Tang ◽  
...  

2015 ◽  
Vol 75 (08) ◽  
pp. 844-847 ◽  
Author(s):  
J. Maier ◽  
E. Schalinski ◽  
C. Häberlein ◽  
U. Gottschalk ◽  
L. Hellmeyer

2009 ◽  
Vol 107 ◽  
pp. S520-S520
Author(s):  
A. Uku ◽  
G. Mohiyiddeen ◽  
M. Raghavan ◽  
J. Wynn ◽  
T. Onon

2020 ◽  
Vol 4 (2) ◽  
pp. 218-230
Author(s):  
Madona Utami Dewi ◽  
Syahredi Syaiful Adnani ◽  
Emilzon Taslim

Maternal cardiac arrest or maternal collaps is defined as an acute event involving the cardiorespiratory systems and/or brain, resulting in a reduced or absent consciousness level (and potentially death), at any stage in pregnancy and up to six weeks after delivery. Perimortem Cesarean Section (PCS) is performed either during maternal cardiac arrest or during impending maternal cardiac arrest toresuscitate mother and fetal. Current recommendations for maternal resuscitation include performance of the procedure following five minutes of unsuccessful cardiopulmonary resuscitation. The most common aetiology of maternal collaps was know as “4 H and  4 T” (Hypovolemia, Hypoxia, Hypo/Hyperkalemia,Hypothermia; Tromboembolism, Toxicity, Tension pneumothorax, Tamponade). Resuscitation in maternal cardiac arrest is mostly similar with non-pregnant patient resuscitation. There are several considerations need to be addressed in primary survey such as endotracheal tube 1 size smaller, supplemental O2 regardless of peripheral saturation, aggressive volume resuscitation, and uterine displacement to relieve compression of the IVC.Keywords: Maternal cardiac arrest; non-pregnant patient resuscitation


Author(s):  
Catherine Williamson

Liver and endocrine diseases are sufficiently common in pregnancy that the majority of obstetricians will manage them regularly. They range from common disorders such as autoimmune hypothyroidism to rare diseases such as acute fatty liver of pregnancy. The liver and endocrine glands play important roles in homeostasis and metabolism, and abnormalities in their functioning can result in adverse outcomes for pregnant women and their children. This chapter describes the presentation and management of pregnancy-specific disorders of the liver and endocrine glands, and also focuses on the commoner disorders of these organs that can occur in women of reproductive age, and therefore which may also have an impact on pregnancy.


2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Mamoru Niikura ◽  
Toshiyuki Fukutomi ◽  
Shoichiro Mineo ◽  
Jiro Mitobe ◽  
Fumie Kobayashi

Abstract Background Liver disease is a common feature of malaria in pregnancy, but its pathogenesis remains unclear. Methods To understand the pathogenesis of liver disease during malaria in pregnancy, comparative proteomic analysis of the liver in a mouse model of malaria in pregnancy was performed. Results Decreased levels of mitochondrial and peroxisomal proteins were observed in the livers of pregnant mice infected with the lethal rodent malaria parasite Plasmodium berghei strain NK65. By contrast, increased levels of perilipin-2, amyloid A-1, and interferon (IFN)-γ signalling pathway-related proteins were observed in the livers of infected pregnant mice, suggesting that IFN-γ signalling may contribute to the development of liver disease during malaria in pregnancy. IFN-γ signalling is a potential trigger of inducible nitric oxide synthase (iNOS) expression. Liver disease associated with microvesicular fatty infiltration and elevated liver enzymes in pregnant wild-type mice infected with malaria parasites was improved by iNOS deficiency. Conclusions In this study, a causative role of iNOS in liver disease associated with microvesicular fatty infiltration during malaria in pregnancy was demonstrated. These findings provide important insight for understanding the role of iNOS-mediated metabolic responses and the pathogenesis of high-risk liver diseases in pregnancy, such as acute fatty liver.


2020 ◽  
Vol 4 (2) ◽  
pp. 249-261
Author(s):  
Madona Utami Dewi ◽  
Syahredi Syaiful Adnani ◽  
Emilzon Taslim

Maternal cardiac arrest or maternal collaps is defined as an acute event involving the cardiorespiratory systems and/or brain, resulting in a reduced or absent consciousness level (and potentially death), at any stage in pregnancy and up to six weeks after delivery. Perimortem Cesarean Section (PCS) is performed either during maternal cardiac arrest or during impending maternal cardiac arrest toresuscitate mother and fetal. Current recommendations for maternal resuscitation include performance of the procedure following five minutes of unsuccessful cardiopulmonary resuscitation. The most common aetiology of maternal collaps was know as “4 H and  4 T” (Hypovolemia, Hypoxia, Hypo/Hyperkalemia,Hypothermia; Tromboembolism, Toxicity, Tension pneumothorax, Tamponade). Resuscitation in maternal cardiac arrest is mostly similar with non-pregnant patient resuscitation. There are several considerations need to be addressed in primary survey such as endotracheal tube 1 size smaller, supplemental O2 regardless of peripheral saturation, aggressive volume resuscitation, and uterine displacement to relieve compression of the IVC.Keywords: Maternal cardiac arrest; non-pregnant patient resuscitation


2021 ◽  
Vol 6 (2) ◽  
pp. 1-5
Author(s):  
Aydin Atis Alev ◽  

To compare factors affecting mortality and morbidity in HELLP (Hemolysis, Elevated Liver Enzyme Levels, and Low Platelets) syndrome & AFLP (Acute fatty liver of pregnancy).


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