Experimental Rocky Mountain Spotted Fever and Endemic Typhus Treated with Prontosil or Sulfapyridine

1939 ◽  
Vol 54 (26) ◽  
pp. 1143 ◽  
Author(s):  
Norman H. Topping
Keyword(s):  
Spotted Fever ◽  
Rocky Mountain ◽  
Rocky Mountain Spotted Fever ◽  
Endemic Typhus

scholarly journals MORPHOLOGICAL STRUCTURE OF RICKETTSIAE

1943 ◽  
Vol 77 (4) ◽  
pp. 355-358 ◽  
Author(s):  
Harry Plotz ◽  
Joseph E. Smadel ◽  
Thomas F. Anderson ◽  
Leslie A. Chambers
Keyword(s):  
Vaccinia Virus ◽  
Q Fever ◽  
Spotted Fever ◽  
Morphological Structure ◽  
Rocky Mountain ◽  
Rocky Mountain Spotted Fever ◽  
Dense Granules ◽  
Endemic Typhus ◽  
Typhus Fever

The morphological structures of the rickettsiae of epidemic and endemic typhus fever, Rocky Mountain spotted fever, and Q fever are similar to one another and to certain bacteria. The rickettsial organisms in common with the elementary bodies of vaccinia virus and all bacteria would appear to have a limiting membrane which surrounds a substance that seems to be protoplasmic in nature; numbers of dense granules are embedded in the inner protoplasm.

scholarly journals Serological Varieties of Typhus Fever

1931 ◽  
Vol 31 (2) ◽  
pp. 225-246 ◽  
Author(s):  
A. Felix ◽  
M. Rhodes
Keyword(s):  
Spotted Fever ◽  
Rocky Mountain ◽  
The United States ◽  
Antigenic Relationship ◽  
Rocky Mountain Spotted Fever ◽  
Antigenic Variant ◽  
Serological Type ◽  
Endemic Typhus ◽  
Typhus Fever ◽  
Source Of Error

1. Fletcher and Lesslar's observations on two serological types of tropical typhus have been fully confirmed.2. The antigenic relationship between the indologenicB. proteusX 19 and the non-indologenic Kingsbury strain is of the same order as that obtaining between the X 19 and X 2 types ofB. proteusX.3. The Kingsbury strain is an antigenic variant derived from the original X 19 culture and represents another serological type ofB. proteusX. The symbol XK is suggested for this type.4. Sera from cases of classical European typhus and of endemic typhus of the United States of America and of Australia have been tested for the occurrence of main and group O agglutinins for the known types ofB. proteusX.5. H agglutination as source of error in the diagnosis of typhus cases is illustrated by some examples.6. Sera from cases of tsutsugamushi from Sumatra and Japan react with type XK like the Malayan cases of this disease described by Fletcher and co-workers.7. This latter reaction is of the order of group O agglutination. It is suggested that antigenically the virus of tsutsugamushi corresponds to another serological type ofB. proteusX which is yet unknown.8. The data published on the serum reactions in Rocky Mountain spotted fever and in the “fièvre exanthématique” of Marseilles are analysed. It is suggested that these two diseases represent further serological varieties of typhus.9. The significance hitherto attached to negative agglutination tests withB. proteusX and to negative cross-immunity tests obtained with some typhuslike diseases requires revision in the light of recent observations.

scholarly journals Rickettsiosis, una enfermedad letal emergente y re-emergente en Colombia

2012 ◽  
Vol 17 (1) ◽  
pp. 82 ◽  
Author(s):  
Juan Carlos Quintero Vélez ◽  
Marylin Hidalgo ◽  
Juan David Rodas González
Keyword(s):  
Key Words ◽  
State Of The Art ◽  
Spotted Fever ◽  
Rocky Mountain ◽  
Future Research ◽  
Rocky Mountain Spotted Fever ◽  
Gram Negative ◽  
The World ◽  
Epidemic Typhus ◽  
Endemic Typhus

<p>Rickettsiosis was first described in Colombia in 1937 by Dr Luis Patiño during an outbreak of a disease with unspecific signs. Rickettsia is a genus of Gram-negative intracellular obligatory bacteria having caused several epidemics around the world, and are transmitted mainly by ticks, fleas, lice and mites. The most fatal within this group of diseases is known as Rocky Mountain Spotted Fever (RMSF), which is caused by Rickettsia rickettsia. There is also the endemic typhus caused by Rickettsia typhi and epidemic typhus caused by Rickettsia prowazekii. In Colombia, several outbreaks of RMSF have occurred during the last decade. The best known among those have hit the municipalities of Necoclí and Turbo, in Antioquia in 2006 and 2008 respectively, and Los Cordobas in the department of Cordoba in 2007. The goal of this review is to describe the state of the art of rickettsiosis, a forgotten lethal disease that has re-emerged in our country, and leave some questions as an inspiration for future research that will hopefully lead scientists to a better understanding of this entity potentially endemic in some areas of Colombia.</p><p><br /><strong>Key words</strong>: outbreak, emerging, reservoir, rickettsiosis, vector, typhus, zoonoses.</p>

Mitbringsel aus den Ferien

Praxis ◽  
2005 ◽  
Vol 94 (47) ◽  
pp. 1869-1870
Author(s):  
Balestra ◽  
Nüesch
Keyword(s):  
Rocky Mountains ◽  
Spotted Fever ◽  
Rocky Mountain ◽  
Rickettsia Conorii ◽  
Rocky Mountain Spotted Fever ◽  
Klinische Diagnose ◽  
Rickettsia Rickettsii

Eine 37-jährige Patientin stellt sich nach der Rückkehr von einer Rundreise durch Nordamerika mit einem Status febrilis seit zehn Tagen und einem makulösem extremitätenbetontem Exanthem seit einem Tag vor. Bei suggestiver Klinik und Besuch der Rocky Mountains wird ein Rocky Mountain spotted fever diagnostiziert. Die Serologie für Rickettsia conorii, die mit Rickettsia rickettsii kreuzreagiert, war positiv und bestätigte die klinische Diagnose. Allerdings konnte der beweisende vierfache Titeranstieg, möglicherweise wegen spät abgenommener ersten Serologie, nicht nachgewiesen werden. Nach zweiwöchiger antibiotischer Therapie mit Doxycycline waren Status febrilis und Exanthem regredient.

Mosquito and Tick-borne Illnesses in the United States. Guidelines for the Recognition and Empiric Treatment of Zoonotic Diseases in the Wilderness.

2019 ◽  
Vol 19 (3) ◽  
pp. 238-257
Author(s):  
Suresh Antony
Keyword(s):  
United States ◽  
Lyme Disease ◽  
Spotted Fever ◽  
Disease Process ◽  
Rocky Mountain ◽  
The United States ◽  
Health Care Facilities ◽  
Diagnostic Tools ◽  
Rocky Mountain Spotted Fever ◽  
Number Of Patients

Background:In the United States, tick-borne illnesses account for a significant number of patients that have been seen and treated by health care facilities. This in turn, has resulted in a significant morbidity and mortality and economic costs to the country.Methods:The distribution of these illnesses is geographically variable and is related to the climate as well. Many of these illnesses can be diagnosed and treated successfully, if recognized and started on appropriate antimicrobial therapy early in the disease process. Patient with illnesses such as Lyme disease, Wet Nile illness can result in chronic debilitating diseases if not recognized early and treated.Conclusion:This paper covers illnesses such as Lyme disease, West Nile illness, Rocky Mountain Spotted fever, Ehrlichia, Tularemia, typhus, mosquito borne illnesses such as enteroviruses, arboviruses as well as arthropod and rodent borne virus infections as well. It covers the epidemiology, clinical features and diagnostic tools needed to make the diagnosis and treat these patients as well.

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