Screening Marine Fungi for Plasmids and Characterization of a Linear Mitochondrial Plasmid in a Lulworthia sp.

Mycologia ◽  
1996 ◽  
Vol 88 (3) ◽  
pp. 350 ◽  
Author(s):  
Carol M. Baisden ◽  
Joseph J. Cooney
Keyword(s):  
Marine Fungi ◽  
Mitochondrial Plasmid ◽  
Linear Mitochondrial Plasmid

Molecular cloning and physical characterization of a Brassica linear mitochondrial plasmid

1987 ◽  
Vol 209 (2) ◽  
pp. 227-233 ◽  
Author(s):  
Tom Turpen ◽  
Stephen J. Garger ◽  
M. David Marks ◽  
Laurence K. Grill
Keyword(s):  
Molecular Cloning ◽  
Physical Characterization ◽  
Mitochondrial Plasmid ◽  
Linear Mitochondrial Plasmid

scholarly journals Multiple approaches for the detection and characterization of viral and plasmid symbionts from a collection of marine fungi

2016 ◽  
Vol 219 ◽  
pp. 22-38 ◽  
Author(s):  
L. Nerva ◽  
M. Ciuffo ◽  
M. Vallino ◽  
P. Margaria ◽  
G.C. Varese ◽  
...  
Keyword(s):  
Marine Fungi

scholarly journals Revelation and characterization of mitochondrial plasmid-like DNA of cotton

1992 ◽  
Vol 8 (3) ◽  
pp. 19-23
Author(s):  
T. Yu. Yusupov ◽  
R. M. Nauruzbaeva ◽  
P. R. Khazratov ◽  
A. P. Ibragimov
Keyword(s):  
Mitochondrial Plasmid

Characterization of Bioactive Compounds from the Red Sea Tunicate-Derived Fungus Penicillium commune DY004

2021 ◽  
Vol 18 ◽  
Author(s):  
Diaa T. A. Youssef ◽  
Lamiaa A. Shaala ◽  
Ameen Almohammadi ◽  
Sameh S. Elhady ◽  
Torki A. Alzughaibi ◽  
...  
Keyword(s):  
Cell Lines ◽  
Red Sea ◽  
Marine Fungi ◽  
Therapeutic Potential ◽  
Ethyl Acetate Extract ◽  
Cyclopiazonic Acid ◽  
Two Dimensional ◽  
Penicillium Commune ◽  
Drug Leads

: As a part of our ongoing interest to identify bioactive microbial secondary metabolites, the Red Sea tunicate-derived Penicillium commune DY004 was investigated. A new dipeptide, penicillizine A (1) together with cyclo(L-Pro-L-Phe) (2), meleagrin (3), α-cyclopiazonic acid (4), and N-(4-hydroxyphenethyl)acetamide (5) was isolated from the ethyl acetate extract of the cultures of the fungus. The structural determinations of 1-5 were supported by interpretation of their one- and two-dimensional nuclear magnetic resonance (NMR) and mass spectrometry (MS) data. In the evaluation of the compounds for their effects against three human tumorous cell lines, meleagrin (3) and α-cyclopiazonic acid (4) displayed the highest and potent activity against HeLa, U373 glioblastoma, and MDA-MB-231 cell lines down up to 3.1 µg/mL. These results suggest that marine fungi are a copious source of drug leads with therapeutic potential. Meleagrin and α-cyclopiazonic acid could be used as potential scaffolds for the development of new and more effective drug leads.

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