Primary Explants of Human Uroepithelium Show an Unusual Response to Low-Dose Irradiation with Cobalt-60 Gamma Rays

1995 ◽  
Vol 142 (2) ◽  
pp. 181 ◽  
Author(s):  
C. Mothersill ◽  
J. Harney ◽  
F. Lyng ◽  
D. Cottell ◽  
K. Parsons ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Dose Irradiation ◽  
Primary Explants

Ovarian Dysfunction in Fetally Irradiated Beagles

1977 ◽  
Vol 35 ◽  
pp. 658-659
Author(s):  
T. M. Seed ◽  
M. H. Sanderson ◽  
D. L. Gutzeit ◽  
T. E. Fritz ◽  
D. V. Tolle ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Long Term Effects ◽  
Ovarian Dysfunction ◽  
Dose Rates ◽  
Highly Sensitive ◽  
Microscopic Evaluation ◽  
Ovarian Pathology ◽  
Normal Offspring

The developing mammalian fetus is thought to be highly sensitive to ionizing radiation. However, dose, dose-rate relationships are not well established, especially the long term effects of protracted, low-dose exposure. A previous report (1) has indicated that bred beagle bitches exposed to daily doses of 5 to 35 R 60Co gamma rays throughout gestation can produce viable, seemingly normal offspring. Puppies irradiated in utero are distinguishable from controls only by their smaller size, dental abnormalities, and, in adulthood, by their inability to bear young.We report here our preliminary microscopic evaluation of ovarian pathology in young pups continuously irradiated throughout gestation at daily (22 h/day) dose rates of either 0.4, 1.0, 2.5, or 5.0 R/day of gamma rays from an attenuated 60Co source. Pups from non-irradiated bitches served as controls. Experimental animals were evaluated clinically and hematologically (control + 5.0 R/day pups) at regular intervals.

Inhibition of Neointimal Proliferation With Low-Dose Irradiation From a β-Particle–Emitting Stent

Circulation ◽  
1996 ◽  
Vol 93 (3) ◽  
pp. 529-536 ◽  
Author(s):  
John R. Laird ◽  
Andrew J. Carter ◽  
William M. Kufs ◽  
Timothy G. Hoopes ◽  
Andrew Farb ◽  
...  
Keyword(s):  
Low Dose ◽  
Dose Irradiation ◽  
Neointimal Proliferation

scholarly journals Low-dose irradiation reduces forced swim test-induced immobility and oxidative stress in mice

2021 ◽  
Vol 165 ◽  
pp. 56-57
Author(s):  
Shota Naoe ◽  
Takahiro Kataoka ◽  
Hina Shuto ◽  
Junki Yano ◽  
Tetsuya Nakada ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Low Dose ◽  
Forced Swim Test ◽  
Swim Test ◽  
Dose Irradiation ◽  
Forced Swim ◽  
And Oxidative Stress

Combined treatments of low dose irradiation with antimicrobials for inactivation of foodborne pathogens on fresh pork

Food Control ◽  
2021 ◽  
Vol 125 ◽  
pp. 107977
Author(s):  
Ziyi Hu ◽  
Yingping Xiao ◽  
Bingkui Wang ◽  
Tony Z. Jin ◽  
Wentao Lyu ◽  
...  
Keyword(s):  
Foodborne Pathogens ◽  
Low Dose ◽  
Combined Treatments ◽  
Dose Irradiation

scholarly journals Low-dose irradiation promotes Rad51 expression by down-regulating miR-193b-3p in hepatocytes

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Eon-Seok Lee ◽  
Yeo Jin Won ◽  
Byoung-Chul Kim ◽  
Daeui Park ◽  
Jin-Han Bae ◽  
...  
Keyword(s):  
Low Dose ◽  
Dose Irradiation

scholarly journals Allogeneic chimerism with low-dose irradiation, antigen presensitization, and costimulator blockade in H-2 mismatched mice

Blood ◽  
2001 ◽  
Vol 97 (2) ◽  
pp. 557-564 ◽  
Author(s):  
Peter J. Quesenberry ◽  
Suju Zhong ◽  
Han Wang ◽  
Marc Stewart
Keyword(s):  
Low Dose ◽  
Great Majority ◽  
Cd40 Ligand ◽  
Third Party ◽  
Whole Body ◽  
Spleen Cells ◽  
Graft Versus Host ◽  
Dose Irradiation ◽  
Unique Model ◽  
High Level

Abstract We have previously shown that the keys to high-level nontoxic chimerism in syngeneic models are stem cell toxic, nonmyelotoxic host treatment as provided by 100-cGy whole-body irradiation and relatively high levels of marrow stem cells. This approach was unsuccessful in H-2 mismatched B6.SJL to BALB/c marrow transplants, but with tolerization, stable multilineage chimerism was obtained. Ten million B6.SJL spleen cells were infused intravenously into BALB/c hosts on day −10 and (MR-1) anti-CD40 ligand monoclonal antibody (mAb) injected intraperitoneally at varying levels on days −10, −7, −3, 0, and +3 and the BALB/c mice irradiated (100 cGy) and infused with 40 million B6.SJL/H-2 mismatched marrow cells on day 0. Stable multilineage chimerism at levels between 30% to 40% was achieved in the great majority of mice at 1.6 mg anti-CD40 ligand mAb per injection out to 64 weeks after transplantation, without graft-versus-host disease. The transplanted mice were also tolerant of donor B6.SJL, but not third-party CBA/J skin grafts at 8 to 9 and 39 to 43 weeks after marrow transplantation. These data provide a unique model for obtaining stable partial chimerism in H-2 mismatched mice, which can be applied to various clinical diseases of man such as sickle cell anemia, thalassemia, and autoimmune disorders.

MicroPET/CT Imaging of an Orthotopic Model of Human Glioblastoma Multiforme and Evaluation of Pulsed Low-Dose Irradiation

2011 ◽  
Vol 80 (3) ◽  
pp. 885-892 ◽  
Author(s):  
Sean S. Park ◽  
John L. Chunta ◽  
John M. Robertson ◽  
Alvaro A. Martinez ◽  
Ching-Yee Oliver Wong ◽  
...  
Keyword(s):  
Glioblastoma Multiforme ◽  
Low Dose ◽  
Ct Imaging ◽  
Orthotopic Model ◽  
Human Glioblastoma ◽  
Dose Irradiation ◽  
Human Glioblastoma Multiforme

Physics must join with biology in better assessing risk from low-dose irradiation

2005 ◽  
Vol 117 (4) ◽  
pp. 346-356 ◽  
Author(s):  
L. E. Feinendegen ◽  
R. D. Neumann
Keyword(s):  
Low Dose ◽  
Dose Irradiation
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