Comparative Long-Term Effects of Liver Damage in the Rat after (a) Localized X-Irradiation and (b) Localized X-Irradiation in the Presence of a Strong Homogeneous Magnetic Field

1974 ◽  
Vol 57 (3) ◽  
pp. 442 ◽  
Author(s):  
O. J. Wordsworth
Keyword(s):  
Magnetic Field ◽  
Liver Damage ◽  
Homogeneous Magnetic Field ◽  
Long Term Effects ◽  
X Irradiation

The Long-Term Effects of X-Irradiation on the Ability of the Spleen to Support Clonogenic Proliferation

1974 ◽  
Vol 58 (3) ◽  
pp. 417 ◽  
Author(s):  
D. F. Nelson ◽  
J. T. Chaffey ◽  
S. Hellman
Keyword(s):  
Long Term Effects ◽  
X Irradiation

Short- and long-term effects of low-dose prenatal X-irradiation in mouse cerebral cortex, with special reference to neuronal migration

1997 ◽  
Vol 93 (5) ◽  
pp. 443-449 ◽  
Author(s):  
S. Fushiki ◽  
Yasuko Hyodo-Taguchi ◽  
Chikako Kinoshita ◽  
Yuji Ishikawa ◽  
Tomohisa Hirobe
Keyword(s):  
Cerebral Cortex ◽  
Special Reference ◽  
Neuronal Migration ◽  
Low Dose ◽  
Long Term Effects ◽  
Mouse Cerebral Cortex ◽  
X Irradiation ◽  
Short And Long Term

scholarly journals Liver damage while Covid-19: problems of pathogenesis and treatment

2021 ◽  
pp. 178-185
Author(s):  
E. A. Lyalyukova ◽  
I. V. Dolgalev ◽  
E. N. Chernysheva ◽  
I. V. Druk ◽  
G. M. Konovalova ◽  
...  
Keyword(s):  
Liver Damage ◽  
Liver Diseases ◽  
Scientific Information ◽  
Organ Damage ◽  
Chronic Liver Diseases ◽  
Long Term Effects ◽  
Initial State ◽  
Cytopathogenic Effect ◽  
Optimal Patient Management

The purpose of the review is to present an analysis of the current literature data on the pathogenesis and therapy of liver damage in Covid-19. Liver damage in COVID-19 patients can be caused by the direct cytopathogenic effect of SARS-CoV-2, an uncontrolled immune response, sepsis, severe hypoxia, or drug damage. In addition, COVID-19 can exacerbate and decompensate previously formed chronic liver diseases with the development of acute liver failure. Physicians should carefully assess the initial state of the liver, and after prescribing therapy, intensify monitoring of its functional state, especially in patients with severe COVID-19. In each clinical case, the doctor needs to establish the possible mechanisms of organ damage in order to select the most optimal patient management tactics, which would take into account all aspects of the COVID-19 course and liver damage. Currently, additional scientific information is required to uncover the features of liver damage during SARS-CoV-2 infection and in the postcovid period. Patients who have undergone COVID-19 need further monitoring to assess the long-term effects of the disease.

Acute and long-term effects of X-irradiation on skeletal growth in the rat

1964 ◽  
Vol 207 (6) ◽  
pp. 1447-1451 ◽  
Author(s):  
Richard D. Phillips ◽  
Donald J. Kimeldorf
Keyword(s):  
Life Span ◽  
End Of Life ◽  
Skeletal Growth ◽  
Sublethal Dose ◽  
X Rays ◽  
Long Term Effects ◽  
Bone Length ◽  
X Irradiation ◽  
Tibia Length

The early and long-term effects of X-irradiation on skeletal growth were investigated with respect to the age at exposure. Rats exposed at a juvenile age (37 days) to a sublethal dose (430 rad) exhibited a retardation in femur, tibia, and tail growth within 14 days after exposure. The maximal deficit was attained within 30 days after exposure and remained approximately constant for the next 300 days. In animals which were exposed to X-rays as young adults (101 days of age), femur and tibia length did not differ from those of controls for the first 2 months after exposure. However, there was a deficit in femur and tibia length in these animals at the end of life span. The magnitude of the bone length reduction at the end of life span was dose dependent. The two major differences in response between the two age groups were the time course of the radiation effect on growth and the magnitude of the deficit. The reduction in bone length occurred faster and was greater in the younger irradiated group.

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