Late Effects of H 3 TDR as a DNA Label on Liver Cell Replication

1967 ◽  
Vol 30 (4) ◽  
pp. 748 ◽  
Author(s):  
Joseph Post ◽  
Joseph Hoffman
1967 ◽  
Vol 34 (1) ◽  
pp. 404-406 ◽  
Author(s):  
Alan D. Sudweeks ◽  
Rolla B. Hill
Keyword(s):  

1968 ◽  
Vol 34 (3) ◽  
pp. 570 ◽  
Author(s):  
Joseph Post ◽  
Joseph Hoffman

Author(s):  
Robert R. Cardell

Hypophysectomy of the rat renders this animal deficient in the hormones of the anterior pituitary gland, thus causing many primary and secondary hormonal effects on basic liver functions. Biochemical studies of these alterations in the rat liver cell are quite extensive; however, relatively few morphological observations on such cells have been recorded. Because the available biochemical information was derived mostly from disrupted and fractionated liver cells, it seemed desirable to examine the problem with the techniques of electron microscopy in order to see what changes are apparent in the intact liver cell after hypophysectomy. Accordingly, liver cells from rats which had been hypophysectomized 5-120 days before sacrifice were studied. Sham-operated rats served as controls and both hypophysectomized and control rats were fasted 15 hours before sacrifice.


1959 ◽  
Vol 37 (6) ◽  
pp. 760-765 ◽  
Author(s):  
S.W. Berkheiser

2011 ◽  
Vol 49 (01) ◽  
Author(s):  
SA Hoffmann ◽  
M Lübberstedt ◽  
U Müller-Vieira ◽  
D Knobeloch ◽  
A Nüssler ◽  
...  

1984 ◽  
Vol 23 (02) ◽  
pp. 87-91 ◽  
Author(s):  
K. Flemming

SummaryIn the beginning of medical radiology, only the benefit of ionizing radiation was obvious, and radiation was handled and applied generously. After late effects had become known, the radiation exposure was reduced to doses following which no such effects were found. Thus, it was assumed that one could obtain an optimal medical benefit without inducing any hazard. Later, due to experimental findings, hypotheses arose (linear dose-effect response, no time factor) which led to the opinion that even low and lowest radiation doses were relevant for the induction of late effects. A radiation fear grew, which was unintentionally strengthened by radiation protection decrees: even for low doses a radiation risk could be calculated. Therefore, it was believed that there could still exist a radiation hazard, and the radiation benefit remained in question. If, however, all presently known facts are considered, one must conclude that large radiation doses are hazardous and low doses are inefficient, whereas lowest doses have a biopositive effect. Ionizing radiation, therefore, may cause both, hazard as well as benefit. Which of the two effects prevails is determined by the level of dose.


2018 ◽  
Vol 56 (08) ◽  
pp. e251-e251
Author(s):  
M Han ◽  
ZC Nwosu ◽  
MP Ebert ◽  
S Hammad ◽  
C Meyer ◽  
...  
Keyword(s):  

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