scholarly journals Chemical Modification of DNA with Muta-Carcinogens. III. Reductive Alkylation of DNA with Mitomycin C.

1985 ◽  
Vol 62 ◽  
pp. 219
Author(s):  
Yuichi Hashimoto ◽  
Koichi Shudo
Keyword(s):  
Chemical Modification ◽  
Mitomycin C ◽  
Reductive Alkylation

Synthesis of 6-O-octyl-β-D-galactopyranosyl-(1 → 5)-L-arabinose and comparative 1-deoxyglycitolation of Nα-Z-L-lysine with amphiphilic lipodisaccharides

1990 ◽  
Vol 68 (12) ◽  
pp. 2253-2257 ◽  
Author(s):  
Daniel Cabaret ◽  
Michel Wakselman
Keyword(s):  
Chemical Modification ◽  
Organic Solvents ◽  
Future Study ◽  
Acyl Transfer ◽  
Protecting Groups ◽  
Reductive Alkylation ◽  
Glycoside Synthesis ◽  
Mild Conditions ◽  
Chemical Modification Of Enzymes

A lipodisaccharide possessing a reactive aldopentose unit, 6-O-octyl-β-D-galactopyranosyl-(1 → 5)-L-arabinose 6, was obtained by glycoside synthesis. To avoid a possible intramolecular acyl transfer, benzoyl protecting groups and mild conditions of detritylation were used in the preparation of the furanosyl acceptor. The reductive alkylation of Nα-Z-L-lysine was then studied and compared to that of previously prepared liposaccharides. In this reaction, amphiphilic five-membered hemiacetals are generally more reactive than their six-membered analogues. The newly prepared disaccharide is the most reactive of the series and also the easiest to prepare. Therefore this reagent has been selected for a future study on the chemical modification of enzymes and the use in organic solvents of the biocatalysts obtained. Keywords: liposaccharides, reductive alkylation.

1570: Combined Mitomycin C and Hyperthermia (SYNERGO) for Patients with Superficial Bladder Cancer (SBC) after Bacillus Calmette-Guerin (BCG) Failure

2007 ◽  
Vol 177 (4S) ◽  
pp. 519-519
Author(s):  
Ofer Nativ ◽  
Renzo Colombo ◽  
Dov Engelstein ◽  
Ofer N. Gofrit ◽  
Thomas Akkad ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Mitomycin C ◽  
Superficial Bladder Cancer ◽  
Bacillus Calmette Guerin ◽  
Bcg Failure

832: Optimized Intravesical Mitomycin C Treatment for Superficial Bladder Cancer: Long-Term Follow-Up

2006 ◽  
Vol 175 (4S) ◽  
pp. 268-269 ◽  
Author(s):  
Jessie L. Au ◽  
Robert A. Badalament ◽  
M. Guillaume Wientjes ◽  
Donn C. Young ◽  
Tong Shen ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Mitomycin C ◽  
Superficial Bladder Cancer ◽  
Long Term Follow Up

Erste Ergebnisse – Die gedeckte Sklerotomie unter primärer Anwendung von Mitomycin C 0,02%

2008 ◽  
Vol 225 (S 04) ◽  
Author(s):  
E Karioris ◽  
C Wirbelauer ◽  
H Häberle ◽  
DT Pham
Keyword(s):  
Mitomycin C ◽  
Erste Ergebnisse

Lokale Applikation von Mitomycin C bei Atemwegsstenosen

Pneumologie ◽  
2009 ◽  
Vol 63 (S 01) ◽  
Author(s):  
PC Bauer ◽  
U Sommerwerck ◽  
J Hagmeyer ◽  
F Bonella ◽  
U Costabel
Keyword(s):  
Mitomycin C
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