Intravascular Catheter Colonization and Related Bloodstream Infection in Critically III Neonates

1990 ◽  
Vol 11 (6) ◽  
pp. 301-308 ◽  
Author(s):  
Wendy A. Cronin ◽  
Teresa P. Germanson ◽  
Leigh G. Donowitz
1990 ◽  
Vol 11 (6) ◽  
pp. 301-308 ◽  
Author(s):  
Wendy A. Cronin ◽  
Teresa P. Germanson ◽  
Leigh G. Donowitz

AbstractIntravascular catheter tip colonization was prospectively evaluated in critically ill neonates to determine its relationship to the type of device used, duration of catheterization, insertion site and nosocomial bloodstream infection. Sixty-one percent (376 of 621) of all intravascular catheter tips were retrieved from 91 infants. Thirteen percent (41 of 310) of peripheral intravenous, 14% (6 of 42) of umbilical, 21% (3 of 11) of central venous, 36% (4 of 11) of peripheral arterial and 100% (2 of 2) of femoral catheters were colonized. Duration of catheterization was significantly longer for colonized lines (p < .001). Eight of 26 (30.8%) peripheral intravenous catheters remaining in place for more than three days were colonized, compared with 33 of 284 (11.6%) at three days or less (p= 0.012). Coagulase-negative staphylococcus was the organism most frequently isolated from catheter tips and bloodstream infections. Catheter colonization rates in this population were higher than those found in adults. Heavily manipulated devices and those in place for longer periods of time were the most frequently colonized.


2003 ◽  
Vol 31 (1) ◽  
pp. 52-59 ◽  
Author(s):  
Marco Ranucci ◽  
Giuseppe Isgrò ◽  
Pier Paolo Giomarelli ◽  
Marco Pavesi ◽  
Aldo Luzzani ◽  
...  

Mycoses ◽  
2004 ◽  
Vol 47 (11-12) ◽  
pp. 491-494 ◽  
Author(s):  
Nathalie Curvale-Fauchet ◽  
Francoise Botterel ◽  
Patrick Legrand ◽  
Jacques Guillot ◽  
Stephane Bretagne

2008 ◽  
Vol 29 (5) ◽  
pp. 424-429 ◽  
Author(s):  
Ahmad Nusair ◽  
Dawn Jourdan ◽  
Sharon Medcalf ◽  
Nedra Marion ◽  
Peter C. Iwen ◽  
...  

Objective.To characterize infection control experience during a 6.5-year period in a cooperative care center for transplant patients.Design.Descriptive analysis.Setting.A cooperative care center for transplanted patients, in which patients and care partners are housed in a homelike environment, and care partners assume responsibility for patient care duties.Patients.Nine hundred ninety one transplant patients.Methods.Infection control definitions from the Centers for Disease Control and Prevention were used to ascertain infection rates. Environmental cultures were used to detect methicillin-resistantStaphylococcus aureus(MRSA), vancomycin-resistantEnterococcus(VRE),Clostridium difficile,and fungi during the first 18 months. Surveillance cultures were performed for a subset of patients and care partners.Results.From June 1999 through December 2005, there were 19,365 patient-days observed. The most common healthcare-associated infection encountered was intravascular catheter-related bloodstream infection, with infection rates of 5.74 and 4.94 cases per 1,000 patient-days for hematopoietic stem cell transplant (HSCT) and solid organ transplant (SOT) patients, respectively. G difficile-associated diarrhea was observed more frequentiy in HSCT patients than in SOT patients (3.97 vs 0.57 cases per 1000 patient-days;P<.0001 ). There was no evidence of environmental contamination with MRSA, VRE, or C.difficile.Acquisition of MRSA was not observed. Acquisition of VRE was documented.Conclusion.This study documented that cooperative care was associated with some risk of healthcare-associated infection, most notably intravascular catheter-associated bloodstream infection and C. difficile-associated diarrhea, it appears the incidences of these infections were roughly commensurate with those in other care settings.


Sign in / Sign up

Export Citation Format

Share Document