Antibiotic lock therapy for salvage of tunneled central venous catheters with catheter colonization and catheter-related bloodstream infection

2018 ◽  
Vol 21 (1) ◽  
pp. e13017 ◽  
Author(s):  
Saurabh Zanwar ◽  
Punit Jain ◽  
Anant Gokarn ◽  
Santhosh Kumar Devadas ◽  
Sachin Punatar ◽  
...  
Keyword(s):  
Bloodstream Infection ◽  
Central Venous Catheters ◽  
Catheter Colonization ◽  
Central Venous ◽  
Lock Therapy ◽  
Antibiotic Lock ◽  
Catheter Related Bloodstream Infection

Impact of oligon central venous catheters on catheter colonization and catheter-related bloodstream infection

2003 ◽  
Vol 31 (1) ◽  
pp. 52-59 ◽  
Author(s):  
Marco Ranucci ◽  
Giuseppe Isgrò ◽  
Pier Paolo Giomarelli ◽  
Marco Pavesi ◽  
Aldo Luzzani ◽  
...  
Keyword(s):  
Bloodstream Infection ◽  
Central Venous Catheters ◽  
Catheter Colonization ◽  
Central Venous ◽  
Catheter Related Bloodstream Infection

Antibiotic-lock therapy in central venous catheter colonization in patients with intestinal failure

2007 ◽  
Vol 54 (4) ◽  
pp. 415-416
Author(s):  
A. Diamanti ◽  
M.S. Basso ◽  
M. Castro ◽  
A. Calce ◽  
M. Gambarara
Keyword(s):  
Central Venous Catheter ◽  
Intestinal Failure ◽  
Venous Catheter ◽  
Catheter Colonization ◽  
Central Venous ◽  
Lock Therapy ◽  
Antibiotic Lock

Prospective Incidence Study of Bloodstream Infection in Infants and Children With Central Venous Catheters After Cardiac Surgery in Italy

2009 ◽  
Vol 30 (7) ◽  
pp. 698-701 ◽  
Author(s):  
Stefania Bezzio ◽  
C. Scolfaro ◽  
R. Broglia ◽  
R. Calabrese ◽  
F. Mignone ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Observational Study ◽  
Bloodstream Infection ◽  
Medical Staff ◽  
Prospective Observational Study ◽  
Central Venous Catheters ◽  
Central Venous ◽  
In Infants And Children ◽  
Catheter Related Bloodstream Infection

This prospective observational study was designed to assess the incidence of, risk factors for, and outcome of catheter-related bloodstream infection in children undergoing cardiac surgery. A staff specifically trained to handle the central venous catheters with proper aseptic techniques and an appropriate patient to medical staff ratio remain the most effective measures to prevent this infection.

scholarly journals Use of Antibiotic Lock Therapy with Long-Term Central Venous Catheters

2018 ◽  
Vol 5 (1) ◽  
Author(s):  
Eluiza Antonieta Moretto ◽  
Paula Elaine Diniz dos Reis ◽  
Christiane Inocêncio Vasques ◽  
Fernanda Titareli Merizio ◽  
Martins Braga ◽  
...  
Keyword(s):  
Central Venous Catheters ◽  
Central Venous ◽  
Lock Therapy ◽  
Antibiotic Lock

scholarly journals Needle-free connectors catheter-related bloodstream infections: a prospective randomized controlled trial

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Michael Koeppen ◽  
Franziska Weinert ◽  
Sabrina Oehlschlaeger ◽  
Andreas Koerner ◽  
Peter Rosenberger ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Bloodstream Infection ◽  
Bacterial Growth ◽  
Bacterial Contamination ◽  
Controlled Trial ◽  
Central Venous Catheters ◽  
Central Venous ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial ◽  
Catheter Related Bloodstream Infection

Abstract Background In the critically ill, catheter-related bloodstream infection can result from bacterial contamination of infusion hubs of intravascular catheters. Needle-free connectors (NFC) have been suggested to reduce the rate of bacterial contamination and subsequent catheter-related bloodstream infection (CRBSI), but data remains ambiguous. Thus, we tested if a novel NFC would reduce bacterial contamination and subsequent CRBSI. Results In a prospective, randomized controlled trial, surgical ICU patients were randomized to three-way hubs closed by caps or Bionecteur® (Vygon, Inc.) of central venous catheters. Every 72 h, infusion lines were renewed and microbiological samples were taken. Bacterial growth was analyzed by blinded microbiologists. Incidence of bacterial contamination and CRSBI were assessed. Outcome parameters like length of stay on ICU and outcome were retrospectively assessed. Two thousand seven hundred patients were screened, 111 were randomized to the NFC, and 109 into the control group. Finally, 24 patients in the NFC and 23 control patients were analyzed. The majority of samples (NFC 77%; control 70%) found no bacterial growth. Coagulase-negative staphylococci were most commonly detected on CVC samples (NFC 17%; control 21%). We found CRBSI (defined as identical pathogens in blood culture and catheter line tip culture, and clinical manifestations of infection) in two control patients and one patient of the NFC group. Their length of ICU stay did not differ between groups (NFC 19 days; control 23 days). Conclusion The use of NFC does not influence the rate of bacterial contamination of infusion hubs of central venous catheters. Trial registration Clinicaltrials.gov, NCT02134769. Registered 09 May 2014.

scholarly journals Tsukamurella catheter-related bloodstream infection in a pediatric patient with pulmonary hypertension

2010 ◽  
Vol 2 (1) ◽  
pp. 5
Author(s):  
Kristen A. Wendorf ◽  
Claudia M. Espinosa ◽  
William D. LeBar ◽  
Jason B. Weinberg
Keyword(s):  
Pulmonary Hypertension ◽  
Bloodstream Infection ◽  
Pediatric Patient ◽  
Bloodstream Infections ◽  
Central Venous Catheters ◽  
Central Venous ◽  
Catheter Related Bloodstream Infection ◽  
Immunocompetent Patients

Catheter-related bloodstream infections (CR-BSI) are important complications in patients with long-term indwelling central venous catheters. In this report, we present the case of a 14-year-old male with pulmonary hypertension treated with continuous treprostinil infusion, who presented with a CR-BSI caused by a Tsukamurella species. This case highlights the potential for this unusual organism to cause infection in immunocompetent patients.

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