Effects of Population Density on the Frequency-Dependent Selection in the Esterase-6 Locus of Drosophila melanogaster

Evolution ◽  
1972 ◽  
Vol 26 (3) ◽  
pp. 313 ◽  
Author(s):  
Ken-ichi Kojima ◽  
Shiu Lan Huang
Evolution ◽  
1973 ◽  
Vol 27 (4) ◽  
pp. 558 ◽  
Author(s):  
R. Nassar ◽  
H. J. Muhs ◽  
R. D. Cook

Genetics ◽  
1979 ◽  
Vol 91 (2) ◽  
pp. 327-338
Author(s):  
R Nassar

ABSTRACT Results of fitness estimates for the Lap locus in Drosophila melanogaster revealed that under crowded media conditions gene frequency equilibrium was maintained by frequency-dependent selection. Evidence was obtained that indicated that mating and egg-to-adult viability were frequency dependent.


2021 ◽  
Author(s):  
Salahuddin Khan ◽  
Janet E. Hill

AbstractNegative frequency-dependent selection is one possible mechanism for maintenance of rare species in communities, but the selective advantage of rare species may be checked at lower overall population densities where resources are abundant. Gardnerella spp. belonging to cpn60 subgroup D, are detected at low levels in vaginal microbiomes and are nutritional generalists relative to other more abundant Gardnerella spp., making them good candidates for negative frequency-dependent selection. The vaginal microbiome is a dynamic environment and the resulting changes in density of the microbiota may explain why subgroup D never gains dominance. To test this, we co-cultured subgroup D isolates with isolates from the more common and abundant subgroup C. Deep amplicon sequencing of rpoB was used to determine proportional abundance of each isolate at 0 h and 72 h in 152 co-cultures, and to calculate change in proportion. D isolates had a positive change in proportional abundance in most co-cultures regardless of initial proportion. Initial density affected the change in proportion of subgroup D isolates either positively or negatively depending on the particular isolates combined, suggesting that growth rate, population density and other intrinsic features of the isolates influenced the outcome. Our results demonstrate that population density is an important factor influencing the outcome of competition between Gardnerella spp. isolated from the human vaginal microbiome.


Genetica ◽  
1979 ◽  
Vol 50 (3) ◽  
pp. 161-166 ◽  
Author(s):  
Gonzalo Alvarez ◽  
Jos� Fari�a ◽  
Antonio Fontdevila

Genetica ◽  
1989 ◽  
Vol 79 (2) ◽  
pp. 77-83 ◽  
Author(s):  
J. C. Adell ◽  
V. Molina ◽  
J. A. Castro ◽  
J. L. Mensua

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