Assessing the Nature of Periodontal Disease Progression-An Application of Covariance Structure Estimation

Author(s):  
J. A. C. Sterne ◽  
A. Kingman ◽  
H. Loe
2018 ◽  
Author(s):  
Murtaza Kaderi ◽  
Mohsin Ali ◽  
Alfiya Ali ◽  
Tasneem Kaderi

The goals of periodontal therapy are to arrest of periodontal disease progression and to attain the regeneration of the periodontal apparatus. Osseous grafting and Guided tissue regeneration (GTR) are the two techniques with the most extensive documentation of periodontal regeneration. However, these techniques offer limited potential towards regenerating the periodontal tissues. Recent surgical procedures and application of newer materials aim at greater and more predictable regeneration with the concept of tissue engineering for enhanced periodontal regeneration and functional attachment have been developed, analyzed, and employed in clinical practice


2009 ◽  
Vol 89 (2) ◽  
pp. 138-142 ◽  
Author(s):  
N. Nishida ◽  
M. Tanaka ◽  
S. Sekine ◽  
T. Takeshita ◽  
K. Nakayama ◽  
...  

The progression of periodontitis may be affected by ALDH2 genotypes with respect to the oxidation of acetaldehyde to acetate, which leads to the accumulation of acetaldehyde in plasma and potential toxic effects. We examined the prospective association of ALDH2 genotypes in terms of alcohol sensitivity between alcohol consumption and periodontal disease progression. In 2003, 224 of 256 (87.5%) individuals examined at baseline (1999) completed probing pocket depth measurements for the evaluation of periodontitis progression. Missing data on self-reported questionnaires and blood samples were excluded; therefore, 183 samples were analyzed. Individuals who consumed ≥ 33.0 g/day of alcohol exhibited high periodontal disease progression risk (OR = 3.54). ALDH2 *1/*2 individuals who consumed ≥ 33 g/day of alcohol displayed a significant odds ratio (OR = 4.28) of periodontitis progression risk, in contrast to ALDH2 *1/*1 individuals. These results suggested that alcohol consumption as well as alcohol sensitivity may be a risk factor for periodontitis progression.


2016 ◽  
Vol 95 (7) ◽  
pp. 822-828 ◽  
Author(s):  
E.K. Kaye ◽  
N. Chen ◽  
H.J. Cabral ◽  
P. Vokonas ◽  
R.I. Garcia

Author(s):  
Ruben Aquino‐Martinez ◽  
Brittany A. Eckhardt ◽  
Jennifer L. Rowsey ◽  
Daniel G. Fraser ◽  
Sundeep Khosla ◽  
...  

1989 ◽  
Vol 26 (2) ◽  
pp. 214-221 ◽  
Author(s):  
Subhash Sharma ◽  
Srinivas Durvasula ◽  
William R. Dillon

The authors report some results on the behavior of alternative covariance structure estimation procedures in the presence of non-normal data. They conducted Monté Carlo simulation experiments with a factorial design involving three levels of skewness, three level of kurtosis, and three different sample sizes. For normal data, among all the elliptical estimation techniques, elliptical reweighted least squares (ERLS) was equivalent in performance to ML. However, as expected, for non-normal data parameter estimates were unbiased for ML and the elliptical estimation techniques, whereas the bias in standard errors was substantial for GLS and ML. Among elliptical estimation techniques, ERLS was superior in performance. On the basis of the simulation results, the authors recommend that researchers use ERLS for both normal and non-normal data.


1989 ◽  
Vol 16 (7) ◽  
pp. 403-411 ◽  
Author(s):  
Panos N. Papapanou ◽  
Jan L. Wennstrom ◽  
Kerstin Grondahl

2001 ◽  
Vol 1 (2) ◽  
pp. 91-94 ◽  
Author(s):  
P. M. L. Manna ◽  
J. E. Costa ◽  
R. S. Gomez

Immunological mechanisms participate in the pathogenesis of human chronic inflammatory periodontal disease (CIPD). Human CD4+lymphocytes express functionally heterogeneous profiles of cytokine production. CD26 is an integral membrane glycoprotein, that is, a marker of Th1-like cytokine development. The purpose of the present study was to compare the immuno-expression of CD26 receptor in periodontal sites with and without clinical attachment loss (CAL). Five patients with rapidly progressing periodontitis and one with juvenile periodontitis were investigated. Each patient presented at least one site with and without CAL. Ten sites with CAL and nine without any CAL were biopsied, followed by the immunohistochemical identification of the CD26 receptor using the MIB-DS2/7 antibody. The results demonstrated that the percentage of positive cells for this antigen in the periodontal sites with CAL was not significantly different from those without attachment loss. Therefore, Th1 cell impairment may not be directly involved with periodontal attachment loss.


2003 ◽  
Vol 74 (2) ◽  
pp. 196-201 ◽  
Author(s):  
Anne-Laure Ejeil ◽  
Frederick Gaultier ◽  
Sylvie Igondjo-Tchen ◽  
Karim Senni ◽  
Bernard Pellat ◽  
...  

2009 ◽  
Vol 36 (10) ◽  
pp. 836-842 ◽  
Author(s):  
Guy Huynh-Ba ◽  
Urs Brägger ◽  
Marcel Zwahlen ◽  
Niklaus P. Lang ◽  
Giovanni E. Salvi

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