scholarly journals Psoriasis in a patient with dermatomyositis

2004 ◽  
Vol 61 (5) ◽  
pp. 557-559 ◽  
Author(s):  
Milos Pavlovic ◽  
Rados Zecevic ◽  
Lidija Zolotarevski
Keyword(s):  
Differential Diagnosis ◽  
Histological Examination ◽  
Inflammatory Bowel Diseases ◽  
Lower Trunk ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Autoimmune Dermatoses ◽  
Psoriatic Lesions ◽  
Rule Out

Psoriasis has been consistently associated with arthritis and inflammatory bowel diseases, though there have been reports on patients with psoriasis and other autoimmune dermatoses. Sometimes, sharply demarcated scaly plaques located over extensor surfaces in patients with dermatomyositis may clinically resemble psoriatic lesions. Histologic findings of interface dermatitis, typical for dermatomyositis, help clinicians to rule out psoriasis. A patient is presented with dermatomyositis in which psoriatic lesions developed over the extremities and lower trunk. Histological examination confirmed the diagnosis of psoriasis. Both diseases have run independent courses. It is prudent to include psoriasis in the differential diagnosis of scaly eruptions occurring in dermatomyositis patients.

scholarly journals Clinical Applications of Raman Spectroscopy in Inflammatory Bowel Diseases. A Review

2018 ◽  
Vol 27 (4) ◽  
pp. 433-438
Author(s):  
Cristian Tefas ◽  
Marcel Tanțău
Keyword(s):  
Ulcerative Colitis ◽  
Raman Spectroscopy ◽  
Differential Diagnosis ◽  
Sensitivity And Specificity ◽  
Inflammatory Bowel Diseases ◽  
High Sensitivity ◽  
Clinical Applications ◽  
Systematic Search ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Background & Aims: Inflammatory bowel diseases are still difficult to diagnose and differentiate in some cases despite the serological, imaging, endoscopic and histopathological armamentarium. Raman spectroscopy is a technique that could help with these shortcomings. The aim of this paper is to present the accuracy of Raman spectroscopy in the diagnosis and monitoring of patients with inflammatory bowel diseases.Methods: We identified the published manuscripts and abstracts up to the 31st of December 2017 by a systematic search of Medline, Embase, Cochrane and other trial registries.Results: Eight publications were found, showing sensitivities and specificities of Raman spectroscopy in diagnosing and differentiating inflammatory bowel diseases ranging from 82 to 99% and 57 to 99%, respectively, and accuracies of up to 95%.Conclusion: The technique has so far proven its potential in the positive and differential diagnosis of Crohn’s disease or ulcerative colitis, allowing for very rapid results with high sensitivity and specificity.

scholarly journals Early arthritis as a rheumatological chameleon: a description of a clinical case

2021 ◽  
Vol 15 (5) ◽  
pp. 80-84
Author(s):  
E. A. Galushko ◽  
A. V. Alekseeva ◽  
G. V. Serikova ◽  
A. S. Semashko
Keyword(s):  
Differential Diagnosis ◽  
Inflammatory Bowel Diseases ◽  
Clinical Picture ◽  
Clinical Case ◽  
Clinical Observation ◽  
Early Arthritis ◽  
Differential Diagnostics ◽  
Extraintestinal Manifestations ◽  
Bowel Diseases ◽  
Inflammatory Bowel

The article discusses the difficulties of differential diagnosis of early arthritis and inflammatory bowel diseases with a predominant clinical picture of extraintestinal manifestations, in particular, articular syndrome. The clinical observation demonstrates features of the course of such conditions, a long diagnostic search and a wide list of diseases included in differential diagnostics range.

Circulating Leptin Levels as a Potential Biomarker in Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Larissa Gabriela Ferreira de Carvalho ◽  
William Gustavo Lima ◽  
Luiz Gonzaga Vaz Coelho ◽  
Valbert Nascimento Cardoso ◽  
Simone Odília Antunes Fernandes
Keyword(s):  
Differential Diagnosis ◽  
Inflammatory Bowel Diseases ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Healthy Controls ◽  
Serum Leptin ◽  
Potential Biomarker ◽  
Significant Difference ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Abstract Background The differential diagnosis of inflammatory bowel diseases (IBDs) between Crohn’s disease (CD) and ulcerative colitis (UC) is important for designing an effective therapeutic regimen. However, without any adequate gold standard method for differential diagnosis currently, therapeutic design remains a major challenge in clinical practice. In this context, recent studies have showed that circulating leptin stands out as a potential biomarker for the categorization of IBDs. Thus, we aimed to summarize the current understanding of the prognostic and diagnostic value of serum leptin in patients with IBDs. Methods A systematic search was performed in PubMed/MEDLINE, Scopus, Cochrane Library, and Web of Science databases. Articles that aimed to study the relationship between circulating levels of leptin and IBDs were included. Finally, the meta-analysis was performed with the mean serum leptin levels in patients with IBDs and healthy controls using RevMan 5.3 software, with I2 > 50% as a criterion for substantial heterogeneity. Results Nineteen studies were included. Serum leptin levels among patients with IBDs and healthy controls did not show a significant difference (95% CI, −2.15 to 0.57; I2, 86%, P ≤ 0.00001). Similarly, there was no association of leptin levels with the activity of IBDs (95% CI, −0.24 to 0.06; I2, 50%; P = 0.13). However, serum leptin levels were significantly higher in patients with CD than those in patients with UC (95% CI, −2.09 to −0.37; I2, 7%; P ≤ 0.36). Conclusion This review suggested that serum leptin levels might be a promising biomarker to help in the differentiation between CD and UC.

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