Diffuse excess mucosal collagen in rectal biopsies facilitates differential diagnosis of solitary rectal ulcer syndrome from other inflammatory bowel diseases

1988 ◽  
Vol 33 (11) ◽  
pp. 1345-1352 ◽  
Author(s):  
Douglas S. Levine ◽  
Christina M. Surawicz ◽  
Terese N. Ajer ◽  
Patrick J. Dean ◽  
Cyrus E. Rubin
2019 ◽  
Vol 11 (3) ◽  
pp. 129-134 ◽  
Author(s):  
Anahita Sadeghi ◽  
Mohammad Biglari ◽  
Mojgan Forootan ◽  
Peyman Adibi

Solitary rectal ulcer syndrome is a multifactorial pathology, which entails a variety of clinical, histologic and endoscopic aspects that needs step-wise logical approach for management especially in relapsing refractory cases. Apart from the diagnostic dilemma that may be faced due to similarities of presentation with inflammatory bowel diseases or colorectal neoplastic lesions, the syndrome also overlaps with dyssynergic defecation syndrome, health anxiety disorder, obsessive compulsive disorder, and latent mucosal rectal prolapse, a systematic composite treatment modality including psychological, pharmacological, physiological and possibly surgical interventions are sometimes essential. Selecting appropriate treatment in this condition not only affects clinical outcome but also patients’ experience and further stigma of SRUS life-long. In this review, we will discuss the detailed pathophysiology, diagnostic and therapeutic approaches in dealing with solitary rectal ulcer syndrome.


2018 ◽  
Vol 27 (4) ◽  
pp. 433-438
Author(s):  
Cristian Tefas ◽  
Marcel Tanțău

Background & Aims: Inflammatory bowel diseases are still difficult to diagnose and differentiate in some cases despite the serological, imaging, endoscopic and histopathological armamentarium. Raman spectroscopy is a technique that could help with these shortcomings. The aim of this paper is to present the accuracy of Raman spectroscopy in the diagnosis and monitoring of patients with inflammatory bowel diseases.Methods: We identified the published manuscripts and abstracts up to the 31st of December 2017 by a systematic search of Medline, Embase, Cochrane and other trial registries.Results: Eight publications were found, showing sensitivities and specificities of Raman spectroscopy in diagnosing and differentiating inflammatory bowel diseases ranging from 82 to 99% and 57 to 99%, respectively, and accuracies of up to 95%.Conclusion: The technique has so far proven its potential in the positive and differential diagnosis of Crohn’s disease or ulcerative colitis, allowing for very rapid results with high sensitivity and specificity.


KYAMC Journal ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 104-107
Author(s):  
Md Benzamin ◽  
Kaniz Fathema ◽  
Dipawnita Saha ◽  
Bodhrun Nahar ◽  
Sharmin Akther ◽  
...  

Solitary rectal ulcer syndrome (SRUS) is an uncommon cause of per rectal bleeding in children. Due to it's wide variety of presentation and rarity, it is frequently misdiagnosed as other clinical condition like inflammatory bowel disease, rectal polyp, amoebiasis or malignancy. Here we presenting a case initially misdiagnosed as ulcerative colitis, latter after thorough evaluation diagnosed as a case of SRUS. KYAMC Journal Vol. 11, No.-2, July 2020, Page 104-107


2004 ◽  
Vol 61 (5) ◽  
pp. 557-559 ◽  
Author(s):  
Milos Pavlovic ◽  
Rados Zecevic ◽  
Lidija Zolotarevski

Psoriasis has been consistently associated with arthritis and inflammatory bowel diseases, though there have been reports on patients with psoriasis and other autoimmune dermatoses. Sometimes, sharply demarcated scaly plaques located over extensor surfaces in patients with dermatomyositis may clinically resemble psoriatic lesions. Histologic findings of interface dermatitis, typical for dermatomyositis, help clinicians to rule out psoriasis. A patient is presented with dermatomyositis in which psoriatic lesions developed over the extremities and lower trunk. Histological examination confirmed the diagnosis of psoriasis. Both diseases have run independent courses. It is prudent to include psoriasis in the differential diagnosis of scaly eruptions occurring in dermatomyositis patients.


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