scholarly journals Case report of Listeria monocytogenes meningoencephalitis in general hospital "Dr Radivoj Simonovic" Sombor

2014 ◽  
Vol 67 (11-12) ◽  
pp. 407-409
Author(s):  
Snezana Delic ◽  
Snezana Brkic ◽  
Aleksandar Delic ◽  
Ivana Cirkovic
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Listeria Monocytogenes ◽  
Therapeutic Option ◽  
Complete Recovery ◽  
Antimicrobial Treatment ◽  
Test Method ◽  
Central Nervous System Infections ◽  
Isolation And Identification

Introduction. Listeria monocytogenes is one of the most common causes of bacterial central nervous system infections in adults. It often affects immunicompromised and elderly patients. Even with appropriate antimicrobial treatment, mortality due to Listeria monocytogenes meningoencephalitis is among the highest of all causes of bacterial central nervous system infections. Case report. We presented a previously healthy, 79-year-old farmer with typical clinical features of meningoencephalitis. The initial treatment with vancomycin and meropenem did not produce any clinical effect. On day six, Listeria monocytogenes was isolated from the cerebrospinal fluid and blood culture and identified by using conventional and automated microbiology methods. Antimicrobial susceptibility testing was performed by E test method. After bacterial isolation and identification, the administration of ampicillin and gentamicin was followed by the complete recovery of our patient. Conclusion. This case is presented to emphasize the negative outcome of empirical treatment when Listeria monocytogenes is not taken into consideration. Furthermore, the administration of ampicillin and gentamicin combination for treatment should be considered as the best therapeutic option in Listeria monocytogenes meningoencephalitis.

scholarly journals Expression of ActA, Ami, InlB, and Listeriolysin O in Listeria monocytogenes of Human and Food Origin

2002 ◽  
Vol 68 (2) ◽  
pp. 616-622 ◽  
Author(s):  
C. Jacquet ◽  
E. Gouin ◽  
D. Jeannel ◽  
P. Cossart ◽  
J. Rocourt
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Listeria Monocytogenes ◽  
Odds Ratio ◽  
Mammalian Cells ◽  
The Other ◽  
Listeriolysin O ◽  
Central Nervous System Infections ◽  
Molecular Weights ◽  
Two Populations

ABSTRACT Expression of proteins involved in the adhesion of Listeria monocytogenes to mammalian cells or in the intracellular life cycle of this bacterium, including listeriolysin O (LLO), ActA, Ami, and InlB, was used to compare two populations of L. monocytogenes strains. One of the populations comprised 300 clinical strains, and the other comprised 150 food strains. All strains expressed LLO, InlB, and ActA. No polymorphism was observed for LLO and InlB. Ami was detected in 283 of 300 human strains and in 149 of 150 food strains. The strains in which Ami was not detected were serovar 4b strains. Based on the molecular weights of the proteins detected, the strains were divided into two groups with Ami (groups Ami1 [75% of the strains] and Ami2 [21%]) and into four groups with ActA (groups ActA1 [52% of the strains], ActA2 [18%], ActA3 [30%], and ActA4 [one strain isolated from food]). Logistic regression showed that food strains were more likely to belong to group ActA3 than human strains (odds ratio [OR] = 2.90; P = 1 � 10−4). Of the strains isolated from patients with non-pregnancy-related cases of listeriosis, bacteremia was predominantly associated with group Ami1 strains (OR = 1.89; P = 1 � 10−2) and central nervous system infections were associated with group ActA2 strains (OR = 3.04; P = 1 � 10−3) and group ActA3 strains (OR = 3.91; P = 1 � 10−3).

scholarly journals Efek samping terapi steroid intravena pada penderita infeksi susunan saraf pusat di Departemen Neurologi RSUP Prof. Dr. R. D. Kandou Manado periode Juli 2014 – Juni 2015

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Ezra L.P Sumampouw ◽  
Arthur H.P. Mawuntu ◽  
Rizal Tumewah
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Side Effects ◽  
Therapeutic Option ◽  
Central Nervous System Infection ◽  
Central Nervous System Infections ◽  
Intravenous Steroid ◽  
Intravenous Steroids ◽  
Brain And Spinal Cord ◽  
Mild Headache

Abstract: Intravenous steroid is a therapeutic option for patients with central nervous system infection to reduce severe inflammation in brain and spinal cord. Albeit, excessive dose and overload duration intravenous steroid can cause variety side effects to the patients from the mildest to the worst, such as headache, gastrointestinal disturbance, or a new kind of infection that may result from intravenous steroid therapy. This was a retrospective cohort study using medical records of patients with central nervous system infection in Prof. R. D. Kandou Manado Hospital period July 2014 to June 2015. There were 22 patients in this study consisted of 16 males and 6 females. Intravenous steroid dexamethasone was the most common steroid administered to 19 patients, followed by methylprednisolone to 3 patients. Mild side effects were found in 72.3 patients and the most common one was mild headache. Conclusion: Intravenous steroids were safe enough as an adjunctive therapy in patients with central nervous system infections in Prof. Dr. R. D. Kandou Hospital Manado. Keywords: central nervous system infection, intravenous steroids, side effects Abstrak: Steroid intravena merupakan terapi pilihan untuk penderita infeksi susunan saraf pusat yang berfungsi mengurangi peradangan pada otak dan sumsum tulang belakang. Pemberian steroid intravena dengan dosis dan durasi yang berlebihan dapat menimbulkan efek samping yang beragam pada penerima terapinya mulai dari ringan hingga yang terberat, seperti nyeri kepala, gangguan gastrointestinal, hingga jenis infeksi baru yang dapat ditimbulkan akibat steroid intravena. Jenis penelitian ialah studi kohort retrospektif berdasarkan data rekam medik pasien dengan infeksi susunan saraf pusat yang dirawat di RSUP Prof. Dr. R. D. Kandou Manado periode Juli 2014 sampai Juni 2015. Terdapat 22 pasien dalam studi ini terdiri dari 16 laki-laki dan 6 perempuan. Jenis steroid intravena deksametason yang terbanyak diberikan pada 19 pasien, disusul metilprednisolon yang diberikan pada 3 pasien. Efek samping ringan ditemukan pada 72,3 kasus dan yang terbanyak ialah nyeri kepala ringan. Simpulan: Steroid intravena cukup aman diberikan sebagai terapi tambahan untuk penyakit infeksi susunan saraf pusat di RSUP Prof. Dr. R. D. Kandou Manado.Kata kunci: infeksi susunan saraf pusat, steroid intravena, efek samping

scholarly journals Genetic Separation of Listeria monocytogenes Causing Central Nervous System Infections in Animals

2018 ◽  
Vol 8 ◽  
Author(s):  
Lisandra Aguilar-Bultet ◽  
Pamela Nicholson ◽  
Lorenz Rychener ◽  
Margaux Dreyer ◽  
Bulent Gözel ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Listeria Monocytogenes ◽  
Central Nervous System Infections

Acute psychotic symptoms caused by overlapping central nervous system pathologies: a case report

2020 ◽  
pp. 376-379
Author(s):  
Gorkem Ugurlu ◽  
Mustafa Ugurlu ◽  
Meltem Kilic ◽  
Zuhal Apaydin ◽  
Ali Caykoylu
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Psychotic Symptoms

Primary central nervous system lymphoma: a case report

2011 ◽  
Vol 31 (7) ◽  
pp. 812-812
Author(s):  
Ai-sheng DONG ◽  
Chang-jing ZUO ◽  
Shao-yan WANG ◽  
Ming-jun GAO ◽  
Xiao-hong LI ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Central Nervous System Lymphoma
Sign in / Sign up

Export Citation Format

Share Document