scholarly journals Synthesis, spectroscopic and biological investigations of di-and triorganotin(IV) derivatives containing germanium: X-ray study of [Ph3GeCH(n-C3H7)CH2CO2]Sn[CH3]3

2006 ◽  
Vol 71 (10) ◽  
pp. 1001-1013 ◽  
Author(s):  
Muhammad Khosa-Kaleem ◽  
Muhammad Mazhar ◽  
Saqib Ali ◽  
Sarim Dastgir ◽  
Masood Parvez ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Antibacterial And Antifungal Activity ◽  
X Ray ◽  
Multinuclear Nmr ◽  
Trigonal Bipyramidal Geometry ◽  
Trigonal Bipyramidal ◽  
Elemental Analyses ◽  
Antibacterial And Antifungal ◽  
Distorted Trigonal Bipyramidal

Bimetallic di- and triorganotin(IV) germanium carboxylates were synthesized and characterized by elemental analyses, as well as IR, multinuclear NMR (1H, 13C, 119Sn) spectroscopy and tested for bioactivity. The structure of the representative compound, [Ph3GeCH(n-C3H7)CH2CO2]Sn[CH3]3, was determined by X-ray analysis and found to have a distorted trigonal bipyramidal geometry around the tin atom. Some selected compounds were also screened against different microbes and showed promising antibacterial and antifungal activity. .

scholarly journals Chemistry and Biological Evaluation of Some New Triazolopyrimidine Derivatives Containing Isopropyl Group

2019 ◽  
pp. 390-396
Author(s):  
Janaki H. Chauhan ◽  
Haresh K. Ram
Keyword(s):  
Antifungal Activity ◽  
1H Nmr ◽  
Biological Evaluation ◽  
Spectroscopic Techniques ◽  
Efficient Synthesis ◽  
Antibacterial And Antifungal Activity ◽  
Isopropyl Group ◽  
Elemental Analyses ◽  
Antibacterial And Antifungal

An efficient Synthesis of a novel series of N,7-bis(substitutedphenyl)-4,7-dihydro-5-isopropyl-[1,2,4]triazolo-[1,5-a]pyrimidine-6-carboxamide (4a-j) was accomplished from N-(substituedphenyl)-4-methyl-3-oxopentanamide, 3-amino-1,2,4-triazole and different aldehyde reflex 20 min with DMF and then after the cooling product was obtained. All the recently synthesized compounds were characterized by the Mass, IR, 1H-NMR and mass spectroscopic techniques and by elemental analyses. The newly synthesized compounds were assessed for their antibacterial and antifungal activity.

Synthesis and characterization of tantalum(V) metallaheterocycle (Me2N)3 and chloro-mixed-amide (Me2N)3Ta(Cl)[N(SiMe3)2]

2003 ◽  
Vol 81 (11) ◽  
pp. 1398-1405 ◽  
Author(s):  
Hu Cai ◽  
Xianghua Yu ◽  
Tianniu Chen ◽  
Xue-Tai Chen ◽  
Xiao-Zeng You ◽  
...  
Keyword(s):  
Solid State ◽  
Hydrogen Abstraction ◽  
Synthesis And Characterization ◽  
Amido Complexes ◽  
X Ray ◽  
Trigonal Bipyramidal Geometry ◽  
Trigonal Bipyramidal ◽  
State 1 ◽  
Distorted Trigonal Bipyramidal

A new mixed-amido complex (Me2N)3Ta(Cl)[N(SiMe3)2] (1) was prepared from the reaction of (Me2N)3TaCl2 with 1 equiv. of LiN(SiMe3)2. The reactions of 1 with 1 equiv. of LiN(SiMe3)2 or (Me2N)3TaCl2 with 2 equiv. of LiN(SiMe3)2 gave (Me2N)3[Formula: see text] (2) with a four-membered metallaheterocyclic ring through γ-hydrogen abstraction. In the solid state, 1 adopts a distorted trigonal bipyramidal geometry with the -N(SiMe3)2 and -Cl ligands in the equatorial and axial positions, respectively. The X-ray structure of 2 reveals that it is in a distorted trigonal bipyramidal geometry with a planar metallaheterocyclic ring.Key words: tantalum, γ-hydrogen abstraction, C-H activation, amido complexes, metallacycle.

Neue Oxopnictate AI3MVO4: Darstellung und Kristallstruktur von A3AsO4 (A = K, Rb, Cs) und K3BiO4 / New Oxopnictates AI3MVO4: Synthesis and Crystal Structure of A3AsO4 (A = K, Rb, Cs) and K3BiO4

2002 ◽  
Vol 57 (6) ◽  
pp. 599-604 ◽  
Author(s):  
Franziska Emmerling ◽  
Mamdouh Idilbi ◽  
Caroline Röhr
Keyword(s):  
Crystal Structure ◽  
Single Crystal ◽  
Crystal Structures ◽  
Close Packing ◽  
Synthesis And Crystal Structure ◽  
X Ray ◽  
Trigonal Bipyramidal Geometry ◽  
Trigonal Bipyramidal ◽  
Centrosymmetric Dimers ◽  
Distorted Trigonal Bipyramidal

Abstract The title compounds have been synthesized via oxidation of the elemental pnicogenes (M = As, Bi) with the hyperoxides AO2 (A = K, Rb, Cs) and their crystal structures were determined on the basis of single crystal X-ray data. In K3AsO4 (orthorhombic, Cccm, a = 1060:1(1), b = 1135:2(1), c = 1694:0(2) pm, Z = 16) and Cs3AsO4(orthorhombic, Pnma, a = 1254:3(2), b = 902:9(2), c = 658:5(3) pm, Z = 4) isolated tetrahedra [AsO4]3- with distances As-O between 167.0 and 170.5 pm are present, which are arranged in a nearly cubic close packing. The structure of K3BiO4 (triclinic, P1̄, a = 643:18(6), b = 657:27(6), c = 762:41(7) pm, α = 101:724(2)°, β = 96:472(2)°, γ = 105:465(2)°, Z = 2) contains centrosymmetric dimers [O3BiO2BiO3]6-, in which the Bi(V) atoms are surrounded by five O atoms in a distorted trigonal bipyramidal geometry with distances Bi-O in the range of 199.5 to 233.1 pm.

Antimicrobial Activity of Some Novel 1-(3-(4-Chlorophenylimino)-3,4- dihydroquinoxalin-2-yl)-3-substituted phenyl-1H-pyrazole-4-carbaldehyde

2020 ◽  
Vol 18 (2) ◽  
pp. 128-134
Author(s):  
Dhanapal Visagaperumal ◽  
Vineeth Chandy
Keyword(s):  
Antimicrobial Activity ◽  
Antifungal Activity ◽  
Dilution Method ◽  
Significant Activity ◽  
Antibacterial And Antifungal Activity ◽  
Reference Drug ◽  
Mass Spectral ◽  
Diffusion Technique ◽  
Elemental Analyses ◽  
Antibacterial And Antifungal

Background: In this study, synthesis of some novel 1-(3-(4-chlorophenylimino)-3,4- dihydroquinoxalin-2-yl)-3-substituted phenyl-1H-pyrazole-4-carbaldehyde were done by cyclization of dehydrated hemiketal using VilsmeierHaack reaction. The structures of synthesized compounds were in accordance of the basis of IR, 1HNMR, Mass spectral data and elemental analyses. The synthesized compounds had given good yields and high purity. Methods: The antimicrobial activity of the synthesized compounds was preliminarily screened by paper disc diffusion technique. The determination of minimum inhibitory concentrations (MIC) of the synthesized compounds were done by using tube dilution method. Results and Conclusion: All the screened compounds showed antibacterial and antifungal activity against selected strains of Gram positive and Gram negative bacteria and two strains of fungus, respectively but exhibited considerably less activity when compared to the reference drug ciprofloxacin and Fluconazole for antibacterial and antifungal activity, respectively. Among the synthesized compounds VV5 exhibited significant activity.

scholarly journals Azo-Hydrazone Tautomerism and Antimicrobial activity of New substituted Imidazolines and Perimidines

2014 ◽  
Vol 10 (5) ◽  
pp. 2694-2704 ◽  
Author(s):  
Thoraya A Farghaly ◽  
Magda A. Abdallah ◽  
Mohamed R. Abdel Aziza
Keyword(s):  
Antimicrobial Activity ◽  
Mass Spectra ◽  
Sodium Hydroxide Solution ◽  
Diazonium Salt ◽  
Acid Ethyl Ester ◽  
Antibacterial And Antifungal Activity ◽  
X Ray ◽  
Excellent Activity ◽  
Elemental Analyses ◽  
Antibacterial And Antifungal

Two new series of 2-{1-[(substitutedphenyl)-hydrazono]-2-oxo-2-phenyl-ethyl}-5,5-diphenyl-3,5-dihydro-imidazol-4-one  and  (1H-Perimidin-2-yl)-[(substitutedphenyl)-hydrazono]-acetic acid ethyl ester were prepared by coupling the diazonium salt of aniline and its derivatives with 2-(2-oxo-2-phenyl-ethylidene)-5,5-diphenyl-imidazolidin-4-one or ethyl 3-dimethylamino-2-(1H-perimidin-2-yl)-propenoate in ethanolic sodium hydroxide solution. The structures of all the newly synthesized compounds were confirmed by spectral (IR, 1H NMR, mass) spectra , and X-ray crystallographic and elemental analyses. Also, the azo-hydrazone tautomerism of these compounds was discussed. In addition, all the newly synthesized compounds were screened for their antibacterial and antifungal activity and the results obtained indicated that some of these compounds exhibited excellent activity.

Crystal and molecular structure of diorganoammonium oxalatotrimethylstannate, [R2NH2][Me3Sn(C2O4)] (R=i-Bu, cyclohexyl)

2011 ◽  
Vol 34 (5-6) ◽  
pp. 127-130 ◽  
Author(s):  
Yaya Sow ◽  
Libasse Diop ◽  
Kieran C. Molloy ◽  
Gabrielle Kociok-Köhn
Keyword(s):  
Molecular Structure ◽  
Hydrogen Bonds ◽  
Diffraction Study ◽  
Crystal And Molecular Structure ◽  
X Ray Diffraction ◽  
X Ray ◽  
Trigonal Bipyramidal ◽  
Trans Complex ◽  
A Chain ◽  
Distorted Trigonal Bipyramidal

Abstract The title compounds [R2NH2][C2O4SnMe3](R=i-Bu, Cy), in which tin atoms adopt a distorted trigonal bipyramidal configuration, have been prepared and submitted to an X-ray diffraction study. These compounds have been obtained from the reaction of (Cy2NH2)2C2O4·H2O or (i-Bu2NH2)2C2O4 with SnMe3Cl. In both [R2NH2][C2O4SnMe3] compounds, the trans complex has an almost regular trigonal bipyramidal geometry around the tin atom. The SnMe3 residues are connected as a chain with bridging oxalate anions in a trans-SnC3O2 framework, the oxygen atoms being in axial positions. The cations connect linear adjacent chains through NH…O hydrogen bonds giving layered structures.

Synthesis of Coumarin Derivatives with Cytotoxic, Antibacterial and Antifungal Activity

2004 ◽  
Vol 19 (4) ◽  
pp. 373-379 ◽  
Author(s):  
Khalid Mohammed Khan ◽  
Zafar S. Saify ◽  
Muhammad Zarrar Khan ◽  
Zia-Ullah ◽  
M. Iqbal Choudhary ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Coumarin Derivatives ◽  
Antibacterial And Antifungal Activity ◽  
Antibacterial And Antifungal
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