scholarly journals Effects of mucuna seed extract on sperm functional integrities and seminal oxidative stress indices of vitrified goat semen

2017 ◽  
Vol 62 (2) ◽  
pp. 155-166
Author(s):  
Daramola Olamitibo ◽  
Oyewusi Adeoye ◽  
Sorongbe Amidu ◽  
Adekunle Oluwafemi ◽  
Iyanda Ayobami ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Liquid Nitrogen ◽  
Seed Extract ◽  
West African ◽  
Stress Indices ◽  
West African Dwarf ◽  
Optimal Values ◽  
Acrosin Activity

Effects of mucuna seed extract (MSE) in tris-extenders on sperm functional integrities and seminal oxidative stress indices of vitrified sperm of West African Dwarf (WAD) goat bucks were investigated. Varying levels (0, 0.25, 0.5, 0.75, 1 g/100 mL of diluent) of MSE in tris-extenders were diluted with semen specimens. Diluted semen specimens were vitrified and preserved in liquid nitrogen. The results showed that sperm functional integrities (acrosome and membrane integrities) in MSE extenders were comparable. However, seminal oxidative stress indices (malondialdehyde [MDA] and acrosin activity) differed (P<0.05) among the various treatments and the control. The results revealed that semen vitrified with MSE had reduced (P<0.05) MDA concentrations compared to the control. Higher (P<0.05) acrosin activities were recorded in semen vitrified with MSE compared to the control except at 0.25g MSE and optimal values were recorded at 1g MSE. The findings indicated that MSE in the tris-extenders reduced MDA concentration with congruent elevated acrosin activity and consequently maintained sperm functional integrities of vitrified spermatozoa of the WAD goat.

scholarly journals Effects of avocado seed extract in different trisextenders on sperm and oxidative stress indices of vitrified goat spermatozoa

2016 ◽  
Vol 61 (4) ◽  
pp. 359-374
Author(s):  
Daramola Olamitibo ◽  
Onanuga Dayo ◽  
Abioja Oladimeji ◽  
Adeleke Mathew ◽  
Olowofeso Olajide ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Citric Acid ◽  
Sodium Phosphate ◽  
Sodium Citrate ◽  
Seed Extract ◽  
West African ◽  
Stress Indices ◽  
Live Sperm ◽  
And Oxidative Stress ◽  
Avocado Seed

Effects of avocado seed extract (ASE) in different tris-extenders on sperm and seminal oxidative stress indices of vitrified spermatozoa of West African Dwarf (WAD) goats during vitrification were assessed. Semen samples were diluted with varying levels (0, 5, 10, 15 and 20 mL/100 mL of diluent) of ASE in tris citric acid (TCA), tris sodium phosphate (TSP) and tris sodium citrate (TSC) extenders while a tris-extender without citric acid, sodium phosphate and sodium citrate served as control. Diluted semen samples were vitrified and preserved. The results revealed higher (P<0.05) progressive sperm motility in TCA extenders at 10%, 15% and 20%, and TSP extender at 20% ASE. Acrosome integrities were higher (P<0.05) in the different tris-extenders at 15% and 20% ASE. TCA, TSP and TSC extenders had higher (P<0.05) membrane integrities at 10%, 15% and 20% ASE. TSP extenders had higher (P<0.05) live sperm at 20% ASE. TCA extenders had higher acrosome reaction while TSP at 20% ASE and TSC at 15% and 20% of ASE had higher sperm capacitation. TCA extender at 20% ASE had reduced malondialdehyde (MDA) concentrations while higher acrosin activities were observed at 20% ASE in TCA extender (P<0.05). The findings indicated that 20% ASE in the tris-extenders improved sperm and oxidative stress indices and the tris-extenders were ranked best in this order: TCA > TSP > TSC.

scholarly journals Assessment of oxidative stress indicators of West African Dwarf sheep under semi intensive management system

2021 ◽  
Vol 43 (2) ◽  
pp. 78-83
Author(s):  
A. A Jack ◽  
O. A. Jimoh ◽  
U. G. Ihejirika ◽  
U. C. Uwaeziozi ◽  
O. O. Adenekan
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Superoxide Dismutase ◽  
Serum Biochemistry ◽  
West African ◽  
Total Antioxidant Activity ◽  
West African Dwarf ◽  
Total Antioxidant ◽  
Serum Biochemical

Oxidative stress results from increased production of free radicals and reactive oxygen species, and a decrease in antioxidant defense. This study was conducted to assess sexual dimorphism in serum biochemistry and oxidative status of West African dwarf lambs. Sixteen each of rams and ewes 8months old were randomly selected from a herd purchase from livestock market, Oyo. The average body weights of the lambs were 12.08±3.26 and 12.76kg ewes and rams, respectively. Fastened blood samples were collected from the sheep and assayed for serum biochemical, lipid peroxidation, total antioxidant activity, catalase and superoxide dismutase using standard procedures, data obtained were subjected to T-test. The result indicated that both sex had similar serum biochemical indices except total protein. Ewes had significantly higher serum protein than ram. Rams had apparently higher total antioxidant activity and significantly higher serum catalase activity than ewes, while serum lipid peroxidation and superoxide dismutase were statistically similar in both sexes. This indicates that rams have better antioxidant activity than ewes. During oxidative stress prone conditions and environment, measures to boost antioxidant activity of ewes should be emphasized.

Assessment of oxidative stress indicators of West African Dwarf sheep under semi intensive management system

2021 ◽  
Vol 43 (1) ◽  
pp. 78-83
Author(s):  
A. A. Jack ◽  
O. A. Jimoh ◽  
U. G. Ihejirika ◽  
U. C, Uwaeziozi ◽  
O. O. Adenekan
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Superoxide Dismutase ◽  
Serum Biochemistry ◽  
West African ◽  
Total Antioxidant Activity ◽  
West African Dwarf ◽  
Total Antioxidant ◽  
Serum Biochemical

Oxidative stress results from increased production of free radicals and reactive oxygen species, and a decrease in antioxidant defense. This study was conducted to assess sexual dimorphism in serum biochemistry and oxidative status of West African dwarf lambs. Sixteen each of rams and ewes 8months old were randomly selected from a herd purchase from livestock market, Oyo. The average body weights of the lambs were 12.08±3.26 and 12.76kg ewes and rams, respectively. Fastened blood samples were collected from the sheep and assayed for serum biochemical, lipid peroxidation, total antioxidant activity, catalase and superoxide dismutase using standard procedures, data obtained were subjected to T-test. The result indicated that both sex had similar serum biochemical indices except total protein. Ewes had significantly higher serum protein than ram. Rams had apparently higher total antioxidant activity and significantly higher serum catalase activity than ewes, while serum lipid peroxidation and superoxide dismutase were statistically similar in both sexes. This indicates that rams have better antioxidant activity than ewes. During oxidative stress prone conditions and environment, measures to boost antioxidant activity of ewes should be emphasized.

scholarly journals The effect of cassia seed extract on the regulation of the LKB1–AMPK–GLUT4 signaling pathway in the skeletal muscle of diabetic rats to improve the insulin sensitivity of the skeletal muscle

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Qiu-Ying Wang ◽  
Ai-Hua Tong ◽  
Ying-Ying Pan ◽  
Xian-Dang Zhang ◽  
Wen-Yu Ding ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Skeletal Muscle ◽  
Blood Glucose ◽  
Lipid Level ◽  
Blood Lipid ◽  
Seed Extract ◽  
Blood Lipid Level ◽  
Stress Indices ◽  
Insulin Tolerance ◽  
And Oxidative Stress

Abstract Background This study aimed to observe the hypoglycemic effect of cassia seed extract in rats with type-2 diabetes mellitus and its effect on reducing insulin resistance in the skeletal muscle. Methods 50 rats were randomly divided into the normal, model, high-dose, middle-dose, and low-dose groups of cassia seed extract (n = 10 each). A high-fat diet combined with streptozotocin administration was adopted to build type 2 diabetes models. The cassia seed extract groups were fed different concentrations cassia seed extract while the normal and model groups were fed the same volume of normal saline. The weight, FINS, GIR, insulin tolerance, blood glucose and blood lipid level, oxidative stress indices and expressions related to the LKB1–AMPK–GLUT4 pathway were detected and compared between the two groups. Results Compared with the normal group, the model group showed lower weight, glucose infusion rate and expressions related to LKB1–AMPK–GLUT4 pathway and higher FINS, insulin tolerance, blood glucose and blood lipid level and oxidative stress indices (all P < 0.05). Compared with the model group, higher weight, glucose infusion rate and expressions related to LKB1–AMPK–GLUT4 pathway and lower FINS, insulin tolerance, blood glucose and blood lipid level and oxidative stress indices were observed in all groups that were administered cassia see extract (all P < 0.05). Conclusion Cassia seed extract could noticeably improve the insulin resistance of diabetic rats and enhance the insulin sensitivity of their skeletal muscles. Its mechanism may be related to damage repair of the LKB1–AMPK–GLUT4 signaling pathway and oxidative stress in the skeletal muscle.

scholarly journals Metabolic and oxidative status of West African dwarf does at different reproductive stages in southwest Nigeria

2019 ◽  
Vol 43 (1) ◽  
Author(s):  
Abubakar Olatunji Jimoh ◽  
Olayinka Abosede Ojo ◽  
Uchechi Daureen Gift Ihejirika
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
First Trimester ◽  
West African ◽  
Late Gestation ◽  
West African Dwarf ◽  
Serum Biochemical

Abstract Background A study was conducted to investigate changes in oxidative stress indicators of West African dwarf (WAD) goats at different reproductive stages. There are a total of 35 dry does, 30 gravid does at first trimester (40–45 days post-mating), 33 gravid does at second trimester (85–90 days post-mating), 31 gravid does at third trimester (135–140 days post-mating), and 40 postpartum does (30–35 days postpartum). Fastened blood samples were collected from all tagged animals and serum obtained. Serum was assayed for lipid peroxidation, total antioxidant activity, glutathione peroxidase, catalase and superoxide dismutase, serum biochemical, glucose, total protein, albumin, cholesterol, triglyceride, high-density lipoprotein, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, urea, and creatinine using standard procedures. Results Result revealed that intense metabolic changes were associated with late prepartum and postpartum does as pronounced in oxidative and biochemical indicators of WAD does. Significant differences were found in serum biochemical indices across the different physiological stages of the doe except for triglyceride and low-density lipoprotein. Antioxidant defense is higher at early and mid-gestation and dry does, through low lipid peroxidation and high antioxidant activity as compared to late gestation and lactation does. Conclusion The observed result shows that the WAD does display oxidative stress during late gestation and lactation owing to intense metabolism. Antioxidant fortification should be employed especially during late gestation and lactation to counteract the oxidative stress in WAD goats.

Growth performance and blood parameters of West African dwarf rams fed dried Ficus thonningii foliage as supplement to high quality cassava peel

Food Chain ◽  
2019 ◽  
Vol 8 (1-2) ◽  
pp. 58-78
Author(s):  
Bazit Bakare ◽  
Olufemi Onifade ◽  
Victoria Ojo ◽  
Kafayat Adebayo ◽  
Anandan Samireddypalle
Keyword(s):  
Growth Performance ◽  
Blood Parameters ◽  
West African ◽  
High Quality ◽  
West African Dwarf ◽  
Ficus Thonningii ◽  
Cassava Peel

scholarly journals Hypoglycemic and antioxidative activities of ethanol seed extract of Hunteria umbellate (Hallier F.) on streptozotocin-induced diabetic rats

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Olubanke O. Ogunlana ◽  
Babatunde O. Adetuyi ◽  
Miracle Rotimi ◽  
lohor Esalomi ◽  
Alaba Adeyemi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Diabetic Rats ◽  
Seed Extract ◽  
The Body ◽  
High Concentration ◽  
Group 5

Abstract Background Diabetes, a global cause of mortality in developing countries is a chronic disorder affecting the metabolism of macromolecules and has been attributed to the defective production and action of insulin characterized by persistent hyperglycemic properties. This global disorder harms organs of the body such as the liver, kidney and spleen. Medicinal plants such as Hunteria umbellate have been shown to possess hypoglycemic, antioxidative and anti-diabetic properties owing to the high concentration of active phytochemical constituents like flavonoids and alkaloids. The present study seeks to evaluate the hypoglycemic activities of ethanolic seed extract of Hunteria umbellate on streptozotocin-induced diabetes rats. Methods Thirty (30) female experimental rats were randomly divided into five groups with six rats per group and were administered streptozotocin (STZ) and Hunteria umbellate as follows. Group 1 served as control and was given only distilled water, group 2 rats were administered 60 mg/kg STZ; Group 3 was administered 60 mg/kg STZ and 100 mg/kg metformin; group 4 rats were administered 60 mg/kg STZ and 800 mg/kg Hunteria umbellate, group 5 rats 60 mg/kg STZ and 400 mg/kg Hunteria umbellate. The fasting blood glucose level of each rat was measured before sacrifice. Rats were then sacrificed 24 h after the last dose of treatment. Results The results showed that Hunteria umbellate significantly reversed STZ-induced increase in fasting blood glucose and increase in body and organs weight of rats. Hunteria umbellate significantly reversed STZ-induced decrease in antioxidant enzyme in liver, kidney and spleen of rats. Hunteria umbellate significantly reversed STZ-induced increase in oxidative stress markers in liver, kidney and spleen of rats. Conclusion Collectively, our results provide convincing information that inhibition of oxidative stress and regulation of blood glucose level are major mechanisms through which Hunteria umbellate protects against streptozotocin-induced diabketes rats.

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