scholarly journals The influence of thymic extract on hematological parameter values in irradiated Wistar rats

2006 ◽  
Vol 56 (2-3) ◽  
pp. 137-148 ◽  
Author(s):  
Jovanovic Milan ◽  
Lazarevic M. ◽  
Popovic N. ◽  
Djurdjevic Dj.
Keyword(s):  
Wistar Rats ◽  
Hematological Parameter ◽  
Thymic Extract ◽  
Parameter Values

Hematological Parameter Values for a Population of Batrachuperus yenyuanensis from West China

2017 ◽  
Vol 12 (3) ◽  
pp. 218-223 ◽  
Author(s):  
Jianli Xiong ◽  
Yanan Zhang ◽  
Qiangqiang Liu ◽  
Yao Min ◽  
Jianping Gou ◽  
...  
Keyword(s):  
Hematological Parameter ◽  
West China ◽  
Parameter Values

scholarly journals The influence of bovine thymic extract on the immune response in irradiated wistar rats

2009 ◽  
Vol 59 (4) ◽  
pp. 331-347
Author(s):  
Jovanovic Milan ◽  
Lazarevic M. ◽  
Popovic N. ◽  
Vojvodic D.
Keyword(s):  
Immune Response ◽  
Wistar Rats ◽  
Thymic Extract

scholarly journals EFFECT OF DIETARY FERMENTED LAMTORO (Leucaena leucocephala) LEAVES FLOUR IN FEED ON DIGESTIBILITY AND HEMATOLOGICAL PARAMETERS OF CATFISH (Clarias sp.)

2019 ◽  
Vol 8 (1) ◽  
pp. 951
Author(s):  
Achmad Noerkhaerin Putra ◽  
Anngy Chahya Pradana ◽  
Deny Novriansyah ◽  
Mustahal Mustahal
Keyword(s):  
Hematological Parameters ◽  
Protein Digestibility ◽  
Raw Material ◽  
Hematological Parameter ◽  
Feed Conversion ◽  
Normal Range ◽  
Physiological Processes ◽  
Final Weight ◽  
And Control ◽  
Parameter Values

Leucaena leaves is a potential ingredient for raw material feed of catfish. The aim of this study is to evaluate the effects of dietary fermented leucaena leaf on digestibility and hematological parameters of catfish. Four treatments and 3 replicates, namely: A (reference feed 70% + leucaena leaves meal 30%), B (reference feed 70%+fermented leucaena leaves meal with A. niger 30%), C (reference feed 70%+fermented leucaena leaves meal with R. oligosporus 30%), and feed D (reference feed 70%+fermented leucaena leaves meal with S. cerevisiae 30%) were used in this study. The juvenile catfish (initial weight was 5,45±0,16 g) are randomly distributed into eighteen tanks with 40 fish per aquarium. Each diet is randomly assigned to the triplicate aquarium and fed to fish three times a day up to satiation for 4 weeks. The results showed that fermented leucaena leaves treatments were significantly higher (P<0.05) than that control in final weight and feed conversion rasio. Nutrients digestibility and final weight were significantly highest (P<0.05) in fermented leucaena leaves with A. niger compared to the other treatment. The value of protein digestibility was significantly highest (P<0.05) in fermented leucaena leaves with A. niger (76,04%), followed by fermented leucaena leaves S. cerevisiae with (69,71%), fermented leucaena leaves meal with R. oligosporus (68,24%), and control (65,18). Leucaena leaves had no effect on physiological processes in catfish, as shown by hematological parameter values that were within the normal range.

scholarly journals Influence of Helleborus odorus W. et K. underground parts extracts on red blood pictures of Wistar rats

2010 ◽  
Vol 64 (3-4) ◽  
pp. 219-229
Author(s):  
Vesna Davidovic ◽  
Miodrag Lazarevic ◽  
Mirjana Joksimovic-Todorovic ◽  
Zoran Maksimovic ◽  
Milan Jovanovic ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Elevated Temperatures ◽  
Haemoglobin Concentration ◽  
Control Group ◽  
Root Extract ◽  
Experimental Conditions ◽  
Sterile Saline ◽  
Red Blood Cell Count ◽  
Physiological Values ◽  
Parameter Values

This paper presents the results of investigations of parameter values of the red blood cell count in Wistar rats, after intramuscular application of rhizome and root extract of Helleborus odorus W. et K (HE). The trial was conducted in experimental conditions on 49 Wistar rats divided into 7 groups with 7 animals per unit (control and six experimental groups). The control group was treated by an intramuscular injection of sterile saline (0.25 ml/100 g BM). For the purpose of determing the duration of the HE effects, the animals were injected with a dose of 10 mg/100 g BMand blood was collected by cardial taps after 24, 48 and 72 hrs. Moreover, we investigated the influence of elevated temperatures on the noted HE extract effects, 24 hrs after the application of the inactivated (56oC 30 min) or denaturized (100oC 5 min) extract, as well as the influence of dialyzed HE. The obtained results of haematological analyses have pointed out the weak hemolyses activity of the extract. In all experimental groups, the erythrocyte count was decreased, but remained within reference values. Haemoglobin concentration and haematocrit values in the experimental and the control groups of rats were decreased in comparison to the physiological values, while the applied extract did not significantly affect the examined parameters. .

Ultrastructural Investigation of Spontaneous Pituitary Adenomas in Aging Sprague-Dawley Rats

1982 ◽  
Vol 40 ◽  
pp. 216-217
Author(s):  
D. J. McComb ◽  
J. Beri ◽  
F. Zak ◽  
K. Kovacs
Keyword(s):  
Microscopic Study ◽  
Pituitary Adenomas ◽  
Wistar Rats ◽  
Microscopic Level ◽  
Sprague Dawley ◽  
Prolactin Cells ◽  
Light Microscopic Level ◽  
Ultrastructural Investigation ◽  
Sprague Dawley Rats ◽  
Long Evans

Investigation of the spontaneous pituitary adenomas in rat have been limited mainly to light microscopic study. Furth et al. (1973) described them as chromophobic, secreting prolactin. Kovacs et al. (1977) in an ul trastructural investigation of adenomas of old female Long-Evans rats, found that they were composed of prolactin cells. Berkvens et al. (1980) using immunocytochemistry at the light microscopic level, demonstrated that some spontaneous tumors of old Wistar rats could contain GH, TSH or ACTH as well as PRL.

Light and electron microscopic investigation of adenohypophyses of germfree, food-restricted, and germfree-food restricted aging, male lobund-wistar rats

1988 ◽  
Vol 46 ◽  
pp. 352-353
Author(s):  
G. Ilse ◽  
K. Kovacs ◽  
N. Ryan ◽  
T. Sano ◽  
L. Stefaneanu ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Microscopic Investigation ◽  
Electron Microscopic Investigation ◽  
Aging Male ◽  
Sprague Dawley ◽  
Electron Microscopic ◽  
Sprague Dawley Rats ◽  
Old Rats ◽  
Ad Libitum ◽  
Microscopic Findings

Germfree state and food restriction have been shown to increase life span and delay tumor occurrence in rats. We report here the histologic, immunocytochemical and electron microscopic findings of adenohypophyses of aging, male Lobund-Wistar rats raised at Lobund Laboratories. In our previous study, the morphologic changes in the adenohypophyses of old rats have been extensively investigated by histology, immunocytochemistry and electron microscopy. Lactotroph adenomas were frequent in Long-Evans and Sprague-Dawley rats, whereas gonadotroph adenomas were frequent in Sprague-Dawley and Wistar rats.Male Lobund-Wistar rats were divided into four groups: 1) conventional, which were raised under normal non-germfree environment and received food ad libitum; 2) germfree-food ad libitum; 3) conventional environment-food restricted and 4) germfree-food restricted. The adenohypophyses were removed from 6-month-, 18-month- and 30-month-old rats. For light microscopy, adenohypophyses were fixed in formalin and embedded in paraffin.

Surface epithelial ultrastructure of the polycystic ovary in the BB wistar rat

1986 ◽  
Vol 44 ◽  
pp. 252-253
Author(s):  
R. C. Kaufmann ◽  
F. K. Khosho ◽  
K. S. Amankwah
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Wistar Rats ◽  
Polycystic Ovary ◽  
Wistar Rat ◽  
Polycystic Ovaries ◽  
Chemical Diabetes ◽  
Scanning Electron

Diabetes decreases the fertility of females, but the mechanisms are not completely understood. In our investigations, we have found that 13% of the female BB Wistar rats that spontaneously developed chemical diabetes had persistent estrous. In this study the ovaries of these rats were examined by scanning electron microscopy(SEM) and compared to normal-cycling controls as well as to rats that had developed polycystic ovaries(PCO) by exposure to constant 1ight.

Structural and functional renal alterations in five-sixth nephrectomized rats on unrestricted diet

1986 ◽  
Vol 44 ◽  
pp. 342-343
Author(s):  
I. Stachura ◽  
M. Pardo ◽  
J. Costello ◽  
D.M. Landwehr
Keyword(s):  
Wistar Rats ◽  
Renal Damage ◽  
Standard Diet ◽  
Experimental Conditions ◽  
Phosphate Intake ◽  
Dietary Restrictions ◽  
Severe Reduction ◽  
Male Wistar Rats ◽  
Unrestricted Diet ◽  
Progressive Renal Insufficiency

Under experimental conditions severe reduction of renal mass results in the hyperfiltration of the remaining nephrons leading to a progressive renal insufficiency. Similar changes are observed in patients with various renal disorders associated with a loss of the functioning nephrons. The progression of renal damage is accelerated by high protein and phosphate intake, and may be modified by the dietary restrictions.We studied 50 five-sixth nephrectarrized male Wistar rats on a standard diet (Rodent Laboratory Chow 5001 Ralston Purina Co., Richmond, Indiana; containing 23.4% protein) over a 20 week period.

Parathyroid gland before and after cisplatin treatment

1987 ◽  
Vol 45 ◽  
pp. 860-861
Author(s):  
S.K. Aggarwal ◽  
J.M. Fadool
Keyword(s):  
Parathyroid Gland ◽  
Wistar Rats ◽  
Antitumor Agent ◽  
The Body ◽  
Cross Linking ◽  
Limiting Factor ◽  
Hormonal Changes ◽  
Primary Mechanism ◽  
Before And After ◽  
Dna Strands

Cisplatin (CDDP) a potent antitumor agent suffers from severe toxic side effects with nephrotoxicity being the major dose-limiting factor, The primary mechanism of its action has been proposed to be through its cross-linking DNA strands. It has also been shown to inactivate various transport enzymes and induce hypocalcemia and hypomagnesemia that may be the underlying cause for some of its toxicities. The present is an effort to study its influence on the parathyroid gland for any hormonal changes that control calcium levels in the body.Male Swiss Wistar rats (Crl: (WI) BR) weighing 200-300 g and of 60 days in age were injected (ip) with cisplatin (7mg/kg in normal saline). The controls received saline injections only. The animals were injected (iv) with calcium (0.5 ml of 10% calcium gluconate/day) and were killed by decapitation on day 1 through 5. Trunk blood was collected in heparinized tubes.

Polychlorinated biphenyl induced hepatocyte alterations

1987 ◽  
Vol 45 ◽  
pp. 716-717
Author(s):  
D.N. Collins ◽  
J.N. Turner ◽  
K.O. Brosch ◽  
R.F. Seegal
Keyword(s):  
Lipid Droplets ◽  
Wistar Rats ◽  
Homovanillic Acid ◽  
Polychlorinated Biphenyl ◽  
Corn Oil ◽  
Environmental Pollutants ◽  
Short Term ◽  
Pcb Congeners ◽  
Urinary Levels ◽  
The Brain

Polychlorinated biphenyls (PCBs) are a ubiquitous class of environmental pollutants with toxic and hepatocellular effects, including accumulation of fat, proliferated smooth endoplasmic recticulum (SER), and concentric membrane arrays (CMAs) (1-3). The CMAs appear to be a membrane storage and degeneration organelle composed of a large number of concentric membrane layers usually surrounding one or more lipid droplets often with internalized membrane fragments (3). The present study documents liver alteration after a short term single dose exposure to PCBs with high chlorine content, and correlates them with reported animal weights and central nervous system (CNS) measures. In the brain PCB congeners were concentrated in particular regions (4) while catecholamine concentrations were decreased (4-6). Urinary levels of homovanillic acid a dopamine metabolite were evaluated (7).Wistar rats were gavaged with corn oil (6 controls), or with a 1:1 mixture of Aroclor 1254 and 1260 in corn oil at 500 or 1000 mg total PCB/kg (6 at each level).

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