scholarly journals NMR diagnostic vallue inassessing laryngeal tumor

2009 ◽  
Vol 56 (3) ◽  
pp. 55-59
Author(s):  
B.A. Banko ◽  
J.P. Milovanovic ◽  
R.M. Maksimovic

Aims: To evaluate diagnostic accuracy of pretreatment surgical magnetic resonance images (MRI) in assessment of patients with tumors of the larynx. Materials and methods: The study included 12 patients, 11 men and 1 women, age 614 years. All patients underwent laryngeal endoscopy and biopsy followed by MRI. The biopsy confirmed that all patient had squamous-cell carcinoma. The MRI images were evaluated for presence in supraglottic, glottic or subglottic region, invasion of submucosal space, cartilage, extension to extralaryngeal tissue, presence of regional lymph nodes in regions I to VII. Imaging data were compared to surgical findings. Results: In 11 patients (92%) the tumor was supraglottic and glotic region and in 1 (8%) subglottic. None of them had tumor only in one region. Paraglottic ivasion was seen in 9 (75%) and preepiglottic in 2 (50%) patients. Paraglottic and preepiglotic invasion in the same time was seen in 3(25%) patients. 7 (58%) patients had normal vocal cord mobility, 3 (25%) mobility was unilateral and 2 (17%) had no vocal cord mobility. Cartilage invasion has not been seen in present study. All patients had billateral limphadenopathy region II-IV. Extension to extralaryngeal tissue was absent. These findings were confirmed on surgery with high diagnostic accuracy. Conclusion: MRI has been shown to be a reliable method for presurgical assessment of patients with tumor of the larynx.

1989 ◽  
Vol 98 (11) ◽  
pp. 907-909 ◽  
Author(s):  
Anthony J. Maniglia ◽  
Brian Dodds ◽  
M. B. Katirji ◽  
Kelly Sorensen ◽  
Mary L. Rosenbaum

This report analyzes the experience gained using two different techniques to reinnervate the paralyzed vocal cord. In the neurotization group, the superior laryngeal nerve (SLN) motor branch–cricothyroid muscle pedicle was used to reinnervate the posterior cricoarytenoid muscle. In the direct nerve anastomosis group, the SLN was anastomosed to the abductor branch of the recurrent laryngeal nerve (RLN), and the ansa hypoglossi (AH) to the adductor branch of the RLN. A third group of animals (control) had the right RLN sectioned without any anastomosis. About 5 to 6 months postoperatively the animals were killed painlessly and evaluated. The neurotization group revealed vocal fold mobilization on the right side to have an average of about half of the mobility of the left, normal side. After the RLN and SLN on the left were severed as well as the AH bilaterally, the vocal cord mobility was reduced to about one fourth. The direct nerve anastomosis group showed about fourfold less vocal cord mobility than the neurotization group. After the SLN, RLN, and AH were severed bilaterally, the control group showed no vocal cord mobility. The neurotization technique has been selected for further experimentation in human adults.


2017 ◽  
Vol 59 (7) ◽  
pp. 798-805 ◽  
Author(s):  
Vivien Richter ◽  
Valerie Hatterman ◽  
Heike Preibsch ◽  
Sonja D Bahrs ◽  
Markus Hahn ◽  
...  

Background Contrast-enhanced spectral mammography (CESM) is a novel breast imaging technique providing comparable diagnostic accuracy to breast magnetic resonance imaging (MRI). Purpose To show that CESM in patients with MRI contraindications is feasible, accurate, and useful as a problem-solving tool, and to highlight its limitations. Material and Methods A total of 118 patients with MRI contraindications were examined by CESM. Histology was obtained in 94 lesions and used as gold standard for diagnostic accuracy calculations. Imaging data were reviewed retrospectively for feasibility, accuracy, and technical problems. The diagnostic yield of CESM as a problem-solving tool and for therapy response evaluation was reviewed separately. Results CESM was more accurate than mammography (MG) for lesion categorization (r = 0.731, P < 0.0001 vs. r = 0.279, P = 0.006) and for lesion size estimation (r = 0.738 vs. r = 0.689, P < 0.0001). Negative predictive value of CESM was significantly higher than of MG (85.71% vs. 30.77%, P < 0.0001). When used for problem-solving, CESM changed patient management in 2/8 (25%) cases. Superposition artifacts and timing problems affected diagnostic utility in 3/118 (2.5%) patients. Conclusion CESM is a feasible and accurate alternative for patients with MRI contraindications, but it is necessary to be aware of the method’s technical limitations.


2021 ◽  
Author(s):  
Valery Visser ◽  
Henry Rusinek ◽  
Johannes Weickenmeier

Abstract Deep and periventricular white matter hyperintensities (dWMH/pvWMH) are bright appearing white matter tissue lesions in T2-weighted fluid attenuated inversion recovery magnetic resonance images and are frequent observations in the aging human brain. While early stages of these white matter lesions are only weakly associated with cognitive impairment, their progressive growth is a strong indicator for long-term functional decline. DWMHs are typically associated with vascular degeneration in diffuse white matter locations; for pvWMHs, however, no unifying theory exists to explain their consistent onset around the horns of the lateral ventricles. We use patient imaging data to create anatomically accurate finite element models of the lateral ventricles, white and gray matter, and cerebrospinal fluid, as well as to reconstruct their WMH volumes. We simulated the mechanical loading of the ependymal cells forming the primary brain-fluid interface, the ventricular wall, and its surrounding tissues at peak ventricular pressure during the hemodynamic cycle. We observe that both the maximum principal tissue strain and the largest ependymal cell stretch consistently localize in the anterior and posterior horns. Our simulations show that ependymal cells experience a loading state that causes the ventricular wall to be stretched thin. Moreover, we show that maximum wall loading coincides with the pvWMH locations observed in our patient scans. These results warrant further analysis of white matter pathology in the periventricular zone that includes a mechanics-driven deterioration model for the ventricular wall.


2018 ◽  
Vol 27 (4) ◽  
pp. 116-121
Author(s):  
Rebecca Shaw ◽  
Cristina Dias ◽  
Jeffrey Ludemann ◽  
Rosemarie Rupps ◽  
Vance Tsai ◽  
...  

Oral Oncology ◽  
2019 ◽  
Vol 90 ◽  
pp. 13-16
Author(s):  
Gabriel C.T.E. Garcia ◽  
Philippe Gorphe ◽  
Dana Hartl ◽  
Samy Ammari ◽  
Caroline Even ◽  
...  

1997 ◽  
Vol 106 (8) ◽  
pp. 705-709 ◽  
Author(s):  
Glenn M. Kaye ◽  
Richard D. Zorowitz ◽  
Soly Baredes

Flexible fiberoptic laryngoscopy is used to evaluate dysphagia, but its clinical utility has not been compared to that of the videofluorographic swallowing study (VFSS). This study correlates parameters of both procedures and identifies laryngoscopy predictors of aspiration in 105 patients. Presence of aspiration, pharyngeal residue, laryngeal sensation, vocal cord mobility, and glottic closure during flexible laryngoscopy (FL), and gag reflex were correlated with aspiration during the VFSS. An algorithm for laryngoscopically detecting aspiration was synthesized. Aspiration (p = .004) and pharyngeal residue (p < .00001) were highly correlated between the two studies. Aspiration during the VFSS was correlated with pharyngeal residue (p < .00001) and laryngeal sensation (p = .027) during FL, but not glottic closure (p = .169) nor vocal cord mobility (p = .056). Patients with a normal gag reflex and without aspiration or pharyngeal residue during FL had a 2.94% risk of aspiration during the VFSS. Flexible laryngoscopy can be used as a relatively safe, portable screening test for aspiration, but cannot always replace the VFSS to identify the presence or cause of aspiration.


2019 ◽  
Vol 12 (3) ◽  
pp. 307-310
Author(s):  
Khatija Y Dalvani ◽  
◽  
Jigisha P Badheka ◽  
Vrinda Oza ◽  
Jaykishan Gol ◽  
...  

2012 ◽  
Vol 36 (4) ◽  
pp. 416-420 ◽  
Author(s):  
Irfan Celebi ◽  
Abdullah S. Mahmutoglu ◽  
Cetin Vural ◽  
Mujdat Bankaoglu ◽  
Kosti C. Caliskan ◽  
...  

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